Central Proliferation and Neurogenesis Is Impaired in Type 2 Diabetes and Prediabetes Animal Models

Rapid β-Amyloid Deposition and Cognitive Impairment After Cholinergic Denervation in APP/PS1 Mice

(2013) Juan Jose Ramos-Rodriguez et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mechanisms of Diabetic Complications

(2013) Josephine M. Forbes et al.   PHYSIOLOGICAL REVIEWS

Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice

(2013) Juan Jose Ramos-Rodriguez et al.   PSYCHONEUROENDOCRINOLOGY

Increased Aβ production prompts the onset of glucose intolerance and insulin resistance

(2012) Margarita Jiménez-Palomares et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Leptin action on nonneuronal cells in the CNS: potential clinical applications

(2012) Weihong Pan et al.   Annals of the New York Academy of Sciences

Insulin resistance in the brain: An old-age or new-age problem?

(2012) Ritchie Williamson et al.   BIOCHEMICAL PHARMACOLOGY

Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis

(2012) Kerry Hunter et al.   BMC NEUROSCIENCE

The effect of ageing on neurogenesis and oxidative stress in the APPswe/PS1deltaE9 mouse model of Alzheimer's disease

(2012) Alison Hamilton et al.   BRAIN RESEARCH

High-fat diet ameliorates neurological deficits caused by defective astrocyte lipid metabolism

(2012) Nutabi Camargo et al.   FASEB JOURNAL

Early Exposure to a High-Fat Diet has more Drastic Consequences on Metabolism Compared with Exposure During Adulthood in Rats

(2012) L. Barella et al.   HORMONE AND METABOLIC RESEARCH

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers

(2012) Theresa R. Bomfim et al.   JOURNAL OF CLINICAL INVESTIGATION

Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression

(2012) Frankie D. Heyward et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Insulin resistance in the nervous system

(2012) Bhumsoo Kim et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Insulin Regulatory Network in Adult Hippocampus and Pancreatic Endocrine System

(2012) Masanao Machida et al.   Stem Cells International

FTY720 Normalizes Hyperglycemia by Stimulating β-Cellin VivoRegeneration indb/dbMice through Regulation of Cyclin D3 and p57KIP2

(2011) Zhengshan Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice

(2011) Mikko Hiltunen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain

(2011) A. Hamilton et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cognitive and Emotional Alterations Are Related to Hippocampal Inflammation in a Mouse Model of Metabolic Syndrome

(2011) Anne-Laure Dinel et al.   PLoS One

Adult hippocampal neurogenesis in aging and Alzheimer's disease

(2010) Lorena Varela-Nallar et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Tissue-specific dysregulation of hexose-6-phosphate dehydrogenase and glucose-6-phosphate transporter production in db/db mice as a model of type 2 diabetes

(2010) Y. Wang et al.   DIABETOLOGIA

Cerebral cortical thickness in patients with type 2 diabetes

(2010) Manon Brundel et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Insulin metabolism and the risk of Alzheimer disease: The Rotterdam Study

(2010) E. M. C. Schrijvers et al.   NEUROLOGY

Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and A  deposition in an Alzheimer mouse model with diabetes

(2010) S. Takeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Metabolic Disorders in Alzheimer Disease and Vascular Dementia

(2009) Suzanne Craft   ARCHIVES OF NEUROLOGY

Increased Tau Phosphorylation and Cleavage in Mouse Models of Type 1 and Type 2 Diabetes

(2009) Bhumsoo Kim et al.   ENDOCRINOLOGY

Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: A link between diabetes and Alzheimer's disease

(2009) Paula L. McClean et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effects of insulinic therapy on cognitive impairment in patients with Alzheimer disease and Diabetes Mellitus type-2

(2009) Massimiliano Plastino et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A high fat diet does not exacerbate CA1 injury and cognitive deficits following global ischemia in rats

(2008) Anastasia P. Arvanitidis et al.   BRAIN RESEARCH

Impaired neurogenesis in adult type-2 diabetic rats

(2008) Bradley T. Lang et al.   BRAIN RESEARCH

GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid

(2008) Victor A. Gault et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Defective insulin signaling pathway and increased glycogen synthase kinase-3 activity in the brain of diabetic mice: Parallels with Alzheimer's disease and correction by insulin

(2008) C.G. Jolivalt et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons

(2008) Alexis M Stranahan et al.   NATURE NEUROSCIENCE

Neuroprotective actions of leptin on central and peripheral neurons in vitro

(2008) G.H. Doherty et al.   NEUROSCIENCE