An In Vivo 11C-(R)-PK11195 PET and In Vitro Pathology Study of Microglia Activation in Creutzfeldt-Jakob Disease

Long-term preclinical magnetic resonance imaging alterations in sporadic Creutzfeldt-Jakob disease

(2016) Gianluigi Zanusso et al.   ANNALS OF NEUROLOGY

Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer’s disease

(2016) Elena Rodriguez-Vieitez et al.   BRAIN

Early and protective microglial activation in Alzheimer’s disease: a prospective study using18F-DPA-714 PET imaging

(2016) Lorraine Hamelin et al.   BRAIN

Immunosenescence of microglia and macrophages: impact on the ageing central nervous system

(2016) Khalil S. Rawji et al.   BRAIN

Mechanisms of prion-induced neurodegeneration

(2016) Paula Saá et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

A neuroprotective role for microglia in prion diseases

(2016) Caihong Zhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MRI abnormalities found 1 year prior to symptom onset in a case of Creutzfeldt–Jakob disease

(2016) Federico Verde et al.   JOURNAL OF NEUROLOGY

Role of Microglia in Neurological Disorders and Their Potentials as a Therapeutic Target

(2016) Li Du et al.   MOLECULAR NEUROBIOLOGY

A polarizing question: do M1 and M2 microglia exist?

(2016) Richard M Ransohoff   NATURE NEUROSCIENCE

11 C-PBR28 binding to translocator protein increases with progression of Alzheimer's disease

(2016) William C. Kreisl et al.   NEUROBIOLOGY OF AGING

Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia

(2015) Zhen Fan et al.   Alzheimers & Dementia

The methodology of TSPO imaging with positron emission tomography

(2015) Federico E. Turkheimer et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease

(2015) Heiko Braak et al.   BRAIN

Roles of microglia in brain development, tissue maintenance and repair

(2015) Mackenzie A. Michell-Robinson et al.   BRAIN

The Role of Neuroinflammation in Dementias

(2015) Giuseppe Pasqualetti et al.   Current Neurology and Neuroscience Reports

Metabolic patterns in prion diseases: an FDG PET voxel-based analysis

(2015) Elena Prieto et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Imaging of neuroinflammation in dementia: a review

(2015) James Stefaniak et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Innate immunity in Alzheimer's disease

(2015) Michael T Heneka et al.   NATURE IMMUNOLOGY

At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei

(2015) Renata Reis et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Microglial Malfunction: The Third Rail in the Development of Alzheimer's Disease

(2015) Siddhita D. Mhatre et al.   TRENDS IN NEUROSCIENCES

The 18 kDa Translocator Protein, Microglia and Neuroinflammation

(2014) Guo-Jun Liu et al.   BRAIN PATHOLOGY

Selective vulnerability to neurodegenerative disease: the curious case of Prion Protein

(2014) W. S. Jackson   Disease Models & Mechanisms

The Role of Neuroimaging in Evaluating Patients Affected by Creutzfeldt-Jakob Disease: A Systematic Review of the Literature

(2014) Federico Caobelli et al.   JOURNAL OF NEUROIMAGING

Immune responses in rapidly progressive dementia: a comparative study of neuroinflammatory markers in Creutzfeldt-Jakob disease, Alzheimer's disease and multiple sclerosis

(2014) Katharina Stoeck et al.   Journal of Neuroinflammation

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

(2014) Marco Prinz et al.   NATURE REVIEWS NEUROSCIENCE

A Standardized [18F]-FDG-PET Template for Spatial Normalization in Statistical Parametric Mapping of Dementia

(2014) Pasquale Anthony Della Rosa et al.   NEUROINFORMATICS

Microglial Dynamics and Role in the Healthy and Diseased Brain

(2014) Diego Gomez-Nicola et al.   NEUROSCIENTIST

Microglia actions in Alzheimer’s disease

(2013) Stefan Prokop et al.   ACTA NEUROPATHOLOGICA

In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease

(2013) William C. Kreisl et al.   BRAIN

M1 and M2 Macrophages: Oracles of Health and Disease

(2013) Charles Mills   CRITICAL REVIEWS IN IMMUNOLOGY

Antiinflammatory effects of apoptotic cells

(2013) Peter M. Henson et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased interleukin-17 in the cerebrospinal fluid in sporadic Creutzfeldt-Jakob disease: a case-control study of rapidly progressive dementia

(2013) Koji Fujita et al.   Journal of Neuroinflammation

Biomarker Modeling of Alzheimer’s Disease

(2013) Clifford R. Jack et al.   NEURON

Prion Diseases

(2013) Leonel Takada et al.   SEMINARS IN NEUROLOGY

Brain microglia were activated in sporadic CJD but almost unchanged in fatal familial insomnia and G114V genetic CJD

(2013) Qi Shi et al.   Virology Journal

Optimization of Supervised Cluster Analysis for Extracting Reference Tissue Input Curves in (R)-[11C]PK11195 Brain PET Studies

(2012) Maqsood Yaqub et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Noninvasive Molecular Imaging of Neuroinflammation

(2012) Andreas H Jacobs et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Evaluation of age-related changes in translocator protein (TSPO) in human brain using 11C-[R]-PK11195 PET

(2012) Ajay Kumar et al.   Journal of Neuroinflammation

Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging

(2012) S. Lavisse et al.   JOURNAL OF NEUROSCIENCE

Early detection of familial Creutzfeldt-Jakob disease on diffusion-weighted imaging before symptom onset

(2012) Yuka Terasawa et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease

(2012) S. Iannaccone et al.   PARKINSONISM & RELATED DISORDERS

Glucose metabolism in sporadic Creutzfeldt-Jakob disease: a statistical parametric mapping analysis of 18F-FDG PET

(2011) E.-J. Kim et al.   EUROPEAN JOURNAL OF NEUROLOGY

Age and disease related changes in the translocator protein (TSPO) system in the human brain: Positron emission tomography measurements with [11C]vinpocetine

(2011) Balázs Gulyás et al.   NEUROIMAGE

Diffusion-weighted MRI hyperintensity patterns differentiate CJD from other rapid dementias

(2011) P. Vitali et al.   NEUROLOGY

Differential Diagnosis for Bilateral Abnormalities of the Basal Ganglia and Thalamus

(2011) Amogh N. Hegde et al.   RADIOGRAPHICS

Prions

(2011) D. W. Colby et al.   Cold Spring Harbor Perspectives in Biology

Correlation of Polydispersed Prion Protein and Characteristic Pathology in the Thalamus in Variant Creutzfeldt-Jakob Disease: Implication of Small Oligomeric Species

(2010) Young Pyo Choi et al.   BRAIN PATHOLOGY

In vivo changes in microglial activation and amyloid deposits in brain regions with hypometabolism in Alzheimer’s disease

(2010) Masamichi Yokokura et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Early detection of sporadic CJD by diffusion-weighted MRI before the onset of symptoms

(2010) K. Satoh et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Incidence and spectrum of sporadic Creutzfeldt–Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification

(2009) Piero Parchi et al.   ACTA NEUROPATHOLOGICA

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Carbon 11–Labeled Pittsburgh Compound B and Carbon 11–Labeled (R)-PK11195 Positron Emission Tomographic Imaging in Alzheimer Disease

(2009) Clayton A. Wiley et al.   ARCHIVES OF NEUROLOGY

Thalamo-striatal diffusion reductions precede disease onset in prion mutation carriers

(2009) Hedok Lee et al.   BRAIN

Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease

(2009) I. Zerr et al.   BRAIN

Microglial activation and amyloid deposition in mild cognitive impairment: A PET study

(2009) A. Okello et al.   NEUROLOGY

Pathologic correlates of diffusion MRI changes in Creutzfeldt-Jakob disease

(2009) D. N. Manners et al.   NEUROLOGY

Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

(2008) Paul Edison et al.   NEUROBIOLOGY OF DISEASE

Ultrastructural study of florid plaques in variant Creutzfeldt-Jakob disease: a comparison with amyloid plaques in kuru, sporadic Creutzfeldt-Jakob disease and Gerstmann-Sträussler-Scheinker disease

(2008) B. Sikorska et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain

(2008) M. Cosenza-Nashat et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Tauopathy in human and experimental variant Creutzfeldt-Jakob disease

(2007) G. Giaccone et al.   NEUROBIOLOGY OF AGING