A practical guide to studying G-quadruplex structures using single-molecule FRET

Reevaluation of the stability of G-quadruplex structures under crowding conditions

(2016) Jun Zhou et al.   BIOCHIMIE

A Comparative Study of G-Quadruplex Unfolding and DNA Reeling Activities of Human RECQ5 Helicase

(2016) Jagat B. Budhathoki et al.   BIOPHYSICAL JOURNAL

The exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium

(2016) Carole Saintomé et al.   NUCLEIC ACIDS RESEARCH

A single molecule study of a fluorescently labeled telomestatin derivative and G-quadruplex interactions

(2016) Parastoo Maleki et al.   NUCLEIC ACIDS RESEARCH

A Personal History of Quadruplex-Small Molecule Targeting

(2015) Stephen Neidle   CHEMICAL RECORD

Dynamics of Fluorescent Dyes Attached to G-Quadruplex DNA and their Effect on FRET Experiments

(2015) Siri Søndergaard  et al.   CHEMPHYSCHEM

Stability and Kinetics of c-MYC Promoter G-Quadruplexes Studied by Single-Molecule Manipulation

(2015) Huijuan You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-throughput sequencing of DNA G-quadruplex structures in the human genome

(2015) Vicki S Chambers et al.   NATURE BIOTECHNOLOGY

ATP-dependent G-quadruplex unfolding by Bloom helicase exhibits low processivity

(2015) Jagat B. Budhathoki et al.   NUCLEIC ACIDS RESEARCH

Folding dynamics and conformational heterogeneity of human telomeric G-quadruplex structures in Na+solutions by single molecule FRET microscopy

(2015) Sofie L. Noer et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex formation in double strand DNA probed by NMM and CV fluorescence

(2015) Alex Kreig et al.   NUCLEIC ACIDS RESEARCH

Native Electrospray Mass Spectrometry of DNA G-Quadruplexes in Potassium Solution

(2014) Adrien Marchand et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

An improved surface passivation method for single-molecule studies

(2014) Boyang Hua et al.   NATURE METHODS

G-quadruplex conformation and dynamics are determined by loop length and sequence

(2014) Ramreddy Tippana et al.   NUCLEIC ACIDS RESEARCH

RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP

(2014) Jagat B. Budhathoki et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding

(2014) S. Ray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomeric Overhang Length Determines Structural Dynamics and Accessibility to Telomerase and ALT-Associated Proteins

(2014) Helen Hwang et al.   STRUCTURE

Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures

(2014) Sujoy Chatterjee et al.   Nature Communications

Surface Passivation for Single-molecule Protein Studies

(2014) Stanley D. Chandradoss et al.   Jove-Journal of Visualized Experiments

RPA-Mediated Unfolding of Systematically Varying G-Quadruplex Structures

(2013) Sujay Ray et al.   BIOPHYSICAL JOURNAL

Discovery of new G-quadruplex binding chemotypes

(2013) Stephan A. Ohnmacht et al.   CHEMICAL COMMUNICATIONS

G-Quadruplex DNA as a Molecular Target for Induced Synthetic Lethality in Cancer Cells

(2013) Keith I. E. McLuckie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single molecule FRET data analysis procedures for FRET efficiency determination: Probing the conformations of nucleic acid structures

(2013) Asger Christian Krüger et al.   METHODS

Evaluation of the Interaction between Long Telomeric DNA and Macrocyclic Hexaoxazole (6OTD) Dimer of a G-quadruplex Ligand

(2013) Keisuke Iida et al.   MOLECULES

Pif1 family helicases suppress genome instability at G-quadruplex motifs

(2013) Katrin Paeschke et al.   NATURE

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection

(2013) Robert Buscaglia et al.   NUCLEIC ACIDS RESEARCH

Kinetic Partitioning Modulates Human Telomere DNA G-Quadruplex Structural Polymorphism

(2013) Xi Long et al.   PLoS One

Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries

(2012) Khondaker M. Rahman et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Isothermal quadruplex priming amplification for DNA-based diagnostics

(2012) Adam Taylor et al.   BIOPHYSICAL CHEMISTRY

A label-free, G-quadruplex DNAzyme-based fluorescent probe for signal-amplified DNA detection and turn-on assay of endonuclease

(2012) Zhixue Zhou et al.   BIOSENSORS & BIOELECTRONICS

Replication Protein A Unfolds G-Quadruplex Structures with Varying Degrees of Efficiency

(2012) Mohammad H. Qureshi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Quadruplex formation as a molecular switch to turn on intrinsically fluorescent nucleotide analogs

(2012) John Johnson et al.   NUCLEIC ACIDS RESEARCH

POT1-TPP1 Regulates Telomeric Overhang Structural Dynamics

(2012) Helen Hwang et al.   STRUCTURE

DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

(2011) Katrin Paeschke et al.   CELL

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

Visualizing Human Telomerase Activity with Primer-Modified Au Nanoparticles

(2011) Jiasi Wang et al.   Small

Temperature-Independent Porous Nanocontainers for Single-Molecule Fluorescence Studies

(2010) Yuji Ishitsuka et al.   ANALYTICAL CHEMISTRY

Interaction of hnRNP A1 with telomere DNA G-quadruplex structures studied at the single molecule level

(2010) A. C. Krüger et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

An RNA G-Quadruplex Is Essential for Cap-Independent Translation Initiation in Human VEGF IRES

(2010) Mark J. Morris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

G-Quadruplex Hinders Translocation of BLM Helicase on DNA: A Real-Time Fluorescence Spectroscopic Unwinding Study and Comparison with Duplex Substrates

(2010) Jia-quan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hydration Is a Major Determinant of the G-Quadruplex Stability and Conformation of the Human Telomere 3′ Sequence of d(AG3(TTAG3)3)

(2010) M. Clarke Miller et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stability of telomeric G-quadruplexes

(2010) Phong Lan Thao Tran et al.   NUCLEIC ACIDS RESEARCH

How long is too long? Effects of loop size on G-quadruplex stability

(2010) Aurore Guédin et al.   NUCLEIC ACIDS RESEARCH

Predicting and understanding the stability of G-quadruplexes

(2009) Oliver Stegle et al.   BIOINFORMATICS

BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation

(2009) Jaya G Yodh et al.   EMBO JOURNAL

Human telomeric G-quadruplex: thermodynamic and kinetic studies of telomeric quadruplex stability

(2009) Jonathan B. Chaires   FEBS Journal

Human telomeric G-quadruplex: structures of DNA and RNA sequences

(2009) Anh Tuân Phan   FEBS Journal

Single Molecule Nanocontainers Made Porous Using a Bacterial Toxin

(2009) Burak Okumus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

G-Quadruplex DNA Bound by a Synthetic Ligand is Highly Dynamic

(2009) Prakrit V. Jena et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

(2009) Jay E. Johnson et al.   NUCLEIC ACIDS RESEARCH

The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

(2009) Cyril Ribeyre et al.   PLoS Genetics

Single molecule conformational analysis of DNA G-quadruplexes

(2008) Pravin S. Shirude et al.   BIOCHIMIE

Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

(2008) Yong Qin et al.   BIOCHIMIE

A practical guide to single-molecule FRET

(2008) Rahul Roy et al.   NATURE METHODS

G-quadruplexes: the beginning and end of UTRs

(2008) Julian Leon Huppert et al.   NUCLEIC ACIDS RESEARCH

Stability and kinetics of G-quadruplex structures

(2008) A. N. Lane et al.   NUCLEIC ACIDS RESEARCH

Genome-wide analysis reveals regulatory role of G4 DNA in gene transcription

(2007) Z. Du et al.   GENOME RESEARCH