RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP

G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD

(2014) Lucas T Gray et al.   Nature Chemical Biology

G-quadruplex conformation and dynamics are determined by loop length and sequence

(2014) Ramreddy Tippana et al.   NUCLEIC ACIDS RESEARCH

Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA

(2014) Ruobo Zhou et al.   eLife

RPA-Mediated Unfolding of Systematically Varying G-Quadruplex Structures

(2013) Sujay Ray et al.   BIOPHYSICAL JOURNAL

Specialization among Iron-Sulfur Cluster Helicases to Resolve G-quadruplex DNA Structures That Threaten Genomic Stability

(2013) Sanjay Kumar Bharti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pif1 family helicases suppress genome instability at G-quadruplex motifs

(2013) Katrin Paeschke et al.   NATURE

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Replication Protein A Unfolds G-Quadruplex Structures with Varying Degrees of Efficiency

(2012) Mohammad H. Qureshi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Multimeric BLM is dissociated upon ATP hydrolysis and functions as monomers in resolving DNA structures

(2012) Ya-Nan Xu et al.   NUCLEIC ACIDS RESEARCH

The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures

(2012) Colleen Barefield et al.   NUCLEIC ACIDS RESEARCH

The Werner Syndrome Protein Is Distinguished from the Bloom Syndrome Protein by Its Capacity to Tightly Bind Diverse DNA Structures

(2012) Ashwini Kamath-Loeb et al.   PLoS One

DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

(2011) Katrin Paeschke et al.   CELL

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase

(2011) Q. Wang et al.   NUCLEIC ACIDS RESEARCH

Folding Equilibrium Constants of Telomere G-Quadruplexes in Free State or Associated with Proteins Determined by Isothermal Differential Hybridization

(2010) Quan Wang et al.   ANALYTICAL CHEMISTRY

Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activity

(2010) Cyril M. Sanders   BIOCHEMICAL JOURNAL

An RNA G-Quadruplex Is Essential for Cap-Independent Translation Initiation in Human VEGF IRES

(2010) Mark J. Morris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

G-Quadruplex Hinders Translocation of BLM Helicase on DNA: A Real-Time Fluorescence Spectroscopic Unwinding Study and Comparison with Duplex Substrates

(2010) Jia-quan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA

(2010) Máté Gyimesi et al.   NUCLEIC ACIDS RESEARCH

Stability of telomeric G-quadruplexes

(2010) Phong Lan Thao Tran et al.   NUCLEIC ACIDS RESEARCH

How long is too long? Effects of loop size on G-quadruplex stability

(2010) Aurore Guédin et al.   NUCLEIC ACIDS RESEARCH

Structure and Cellular Roles of the RMI Core Complex from the Bloom Syndrome Dissolvasome

(2010) Kelly A. Hoadley et al.   STRUCTURE

An Unusually Stable G-Quadruplex within the 5′-UTR of the MT3 Matrix Metalloproteinase mRNA Represses Translation in Eukaryotic Cells

(2009) Mark J. Morris et al.   BIOCHEMISTRY

Kinetic Mechanism of DNA Unwinding by the BLM Helicase Core and Molecular Basis for Its Low Processivity

(2009) Ye Yang et al.   BIOCHEMISTRY

Predicting and understanding the stability of G-quadruplexes

(2009) Oliver Stegle et al.   BIOINFORMATICS

BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation

(2009) Jaya G Yodh et al.   EMBO JOURNAL

Human telomeric G-quadruplex: thermodynamic and kinetic studies of telomeric quadruplex stability

(2009) Jonathan B. Chaires   FEBS Journal

RecQ helicases: Multiple structures for multiple functions?

(2009) Alessandro Vindigni et al.   HFSP Journal

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression

(2009) Himesh Fernando et al.   NUCLEIC ACIDS RESEARCH

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

(2009) Jay E. Johnson et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex structures: in vivo evidence and function

(2009) Hans J. Lipps et al.   TRENDS IN CELL BIOLOGY

The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

(2009) Cyril Ribeyre et al.   PLoS Genetics

Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

(2008) Yong Qin et al.   BIOCHIMIE

Kinetics and mechanism of K+- and Na+-induced folding of models of human telomeric DNA into G-quadruplex structures

(2008) Robert D. Gray et al.   NUCLEIC ACIDS RESEARCH

Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes

(2008) Johanna Eddy et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes: the beginning and end of UTRs

(2008) Julian Leon Huppert et al.   NUCLEIC ACIDS RESEARCH

Stability and kinetics of G-quadruplex structures

(2008) A. N. Lane et al.   NUCLEIC ACIDS RESEARCH

Genome-wide analysis reveals regulatory role of G4 DNA in gene transcription

(2007) Z. Du et al.   GENOME RESEARCH