Glyoxalase 2 drives tumorigenesis in human prostate cells in a mechanism involving androgen receptor and p53-p21 axis

AR-Signaling in Human Malignancies: Prostate Cancer and Beyond

(2017) Michael Schweizer et al.   Cancers

Diagnostic potential in prostate cancer of a panel of urinary molecular tumor markers

(2017) Vincenzo N. Talesa et al.   Cancer Biomarkers

The Potential of MicroRNAs as Prostate Cancer Biomarkers

(2016) Linda Fabris et al.   EUROPEAN UROLOGY

Tetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01

(2016) Kotohiko Kimura et al.   PLoS One

Tumor suppressor p53 and its mutants in cancer metabolism

(2015) Juan Liu et al.   CANCER LETTERS

Methylglyoxal, the foe and friend of glyoxalase and Trx/TrxR systems in HT22 nerve cells

(2015) A.L. Dafre et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epigenomic profiling of DNA methylation in paired prostate cancer versus adjacent benign tissue

(2015) Milan S. Geybels et al.   PROSTATE

Mitochondrial Proteins Moonlighting in the Nucleus

(2015) Richard M. Monaghan et al.   TRENDS IN BIOCHEMICAL SCIENCES

Overexpression of TREM2 enhances glioma cell proliferation and invasion: a therapeutic target in human glioma

(2015) Xiao-Qiang Wang et al.   Oncotarget

Glyoxalase I inhibition induces apoptosis in irradiated MCF-7 cells via a novel mechanism involving Hsp27, p53 and NF-κB

(2014) C Antognelli et al.   BRITISH JOURNAL OF CANCER

Androgens and androgen receptor signaling in prostate tumorigenesis

(2014) Ye Zhou et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer

(2014) F Hosoda et al.   ONCOGENE

Nrf1 and Nrf2 Transcription Factors Regulate Androgen Receptor Transactivation in Prostate Cancer Cells

(2014) Michelle A. Schultz et al.   PLoS One

Reactive oxygen species induce apoptosis in bronchial epithelial BEAS-2B cells by inhibiting the antiglycation glyoxalase I defence: involvement of superoxide anion, hydrogen peroxide and NF-κB

(2013) Cinzia Antognelli et al.   APOPTOSIS

The glyoxalase pathway: the first hundred years… and beyond

(2013) Marta Sousa Silva et al.   BIOCHEMICAL JOURNAL

Glyoxalase 1 is up-regulated in hepatocellular carcinoma and is essential for HCC cell proliferation

(2013) Xiaohui Hu et al.   BIOTECHNOLOGY LETTERS

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Comparison of p40 (ΔNp63) and p63 expression in prostate tissues - which one is the superior diagnostic marker for basal cells?

(2013) Verena Sailer et al.   HISTOPATHOLOGY

Glyoxalase 1−419C>A Variant Is Associated with Oxidative Stress: Implications in Prostate Cancer Progression

(2013) Cinzia Antognelli et al.   PLoS One

Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells

(2013) T. Stoyanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring glyoxalase 1 expression in prostate cancer tissues: Targeting the enzyme by ethyl pyruvate defangs some malignancy-associated properties

(2013) Martin Baunacke et al.   PROSTATE

oPOSSUM-3: Advanced Analysis of Regulatory Motif Over-Representation Across Genes or ChIP-Seq Datasets

(2013) Andrew T. Kwon et al.   G3-Genes Genomes Genetics

Metformin sensitizes endometrial cancer cells to chemotherapy by repressing glyoxalase I expression

(2012) Lingling Dong et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Metabolic Enzyme IMPDH Is Also a Transcription Factor Regulated by Cellular State

(2012) Elena N. Kozhevnikova et al.   MOLECULAR CELL

Role of glyoxalase I in the proliferation and apoptosis control of human LNCaP and PC3 prostate cancer cells

(2012) Cinzia Antognelli et al.   PROSTATE

Human Epithelial Basal Cells Are Cells of Origin of Prostate Cancer, Independent of CD133 Status

(2012) Renea A. Taylor et al.   STEM CELLS

Androgens regulate Hedgehog signalling and proliferation in androgen-dependent prostate cells

(2011) Nanor Sirab et al.   INTERNATIONAL JOURNAL OF CANCER

Common Gene Rearrangements in Prostate Cancer

(2011) Mark A. Rubin et al.   JOURNAL OF CLINICAL ONCOLOGY

Up-Regulation of Sonic Hedgehog Contributes to TGF-β1-Induced Epithelial to Mesenchymal Transition in NSCLC Cells

(2011) Ma'in Y. Maitah et al.   PLoS One

The curcumin analog ca27 down-regulates androgen receptor through an oxidative stress mediated mechanism in human prostate cancer cells

(2011) Alexandra M. Fajardo et al.   PROSTATE

Glyoxalase in diabetes, obesity and related disorders

(2011) Naila Rabbani et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Identification of a Cell of Origin for Human Prostate Cancer

(2010) A. S. Goldstein et al.   SCIENCE

Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1

(2009) Christopher M. Cabello et al.   BIOCHEMICAL PHARMACOLOGY

The combination of urine DD3PCA3mRNA and PSA mRNA as molecular markers of prostate cancer

(2009) Ettore Mearini et al.   BIOMARKERS

Depletion of intrinsic expression of Interleukin-8 in prostate cancer cells causes cell cycle arrest, spontaneous apoptosis and increases the efficacy of chemotherapeutic drugs

(2009) Rajendra K Singh et al.   Molecular Cancer

A luminal epithelial stem cell that is a cell of origin for prostate cancer

(2009) Xi Wang et al.   NATURE