Neutrophils in cancer: prognostic role and therapeutic strategies

Change in Neutrophil-to-lymphocyte Ratio in Response to Targeted Therapy for Metastatic Renal Cell Carcinoma as a Prognosticator and Biomarker of Efficacy

(2016) Arnoud J. Templeton et al.   EUROPEAN UROLOGY

Occurrence and significance of tumor-associated neutrophils in patients with colorectal cancer

(2016) Maria Rosaria Galdiero et al.   INTERNATIONAL JOURNAL OF CANCER

Immunotherapy Combined or Sequenced With Targeted Therapy in the Treatment of Solid Tumors: Current Perspectives

(2016) Michael B. Atkins et al.   JNCI-Journal of the National Cancer Institute

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells

(2016) A. Spiegel et al.   Cancer Discovery

Immunotherapy Combined or Sequenced With Targeted Therapy in the Treatment of Solid Tumors: Current Perspectives

(2016) Michael B. Atkins et al.   JNCI-Journal of the National Cancer Institute

Neutrophils: important contributors to tumor progression and metastasis

(2015) Agnieszka Swierczak et al.   CANCER AND METASTASIS REVIEWS

Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells

(2015) M. Bodogai et al.   CANCER RESEARCH

The wound inflammatory response exacerbates growth of pre-neoplastic cells and progression to cancer

(2015) N. Antonio et al.   EMBO JOURNAL

CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study

(2015) Philippe A Cassier et al.   LANCET ONCOLOGY

MET is required for the recruitment of anti-tumoural neutrophils

(2015) Veronica Finisguerra et al.   NATURE

Neutrophils support lung colonization of metastasis-initiating breast cancer cells

(2015) Stefanie K. Wculek et al.   NATURE

Immune-mediated mechanisms influencing the efficacy of anticancer therapies

(2015) Seth B. Coffelt et al.   TRENDS IN IMMUNOLOGY

Clinical variables associated with PSA response to abiraterone acetate in patients with metastatic castration-resistant prostate cancer

(2014) R. Leibowitz-Amit et al.   ANNALS OF ONCOLOGY

Baseline neutrophil–lymphocyte ratio (NLR) is associated with survival and response to treatment with second-line chemotherapy for advanced prostate cancer independent of baseline steroid use

(2014) D. Lorente et al.   ANNALS OF ONCOLOGY

Neutrophil-to-lymphocyte ratio as a prognostic biomarker for men with metastatic castration-resistant prostate cancer receiving first-line chemotherapy: data from two randomized phase III trials†

(2014) R. J. van Soest et al.   ANNALS OF ONCOLOGY

Simple prognostic score for metastatic castration-resistant prostate cancer with incorporation of neutrophil-to-lymphocyte ratio

(2014) Arnoud J. Templeton et al.   CANCER

Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy

(2014) Carola H. Ries et al.   CANCER CELL

Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Solid Tumors: A Systematic Review and Meta-Analysis

(2014) Arnoud J. Templeton et al.   JNCI-Journal of the National Cancer Institute

The clinical significance of tumor-infiltrating neutrophils and neutrophil-to-CD8+ lymphocyte ratio in patients with resectable esophageal squamous cell carcinoma

(2014) Jianbo Wang et al.   Journal of Translational Medicine

Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells

(2014) K. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of CXCR2-Mediated MDSC Tumor Trafficking Enhances Anti-PD1 Efficacy

(2014) S. L. Highfill et al.   Science Translational Medicine

An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy

(2013) Alicia S Chung et al.   NATURE MEDICINE

Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice

(2012) Junjie Mei et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis

(2012) Thomas Jamieson et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung

(2011) Zvi Granot et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Tumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent Mechanism

(2011) Jeremy D. Waight et al.   PLoS One

Polymorphonuclear granulocytes in human head and neck cancer: Enhanced inflammatory activity, modulation by cancer cells and expansion in advanced disease

(2010) Sokratis Trellakis et al.   INTERNATIONAL JOURNAL OF CANCER

Neutrophil elastase–mediated degradation of IRS-1 accelerates lung tumor growth

(2010) A McGarry Houghton et al.   NATURE MEDICINE

Preclinical development of molecular-targeted agents for cancer

(2010) Alberto Ocana et al.   Nature Reviews Clinical Oncology

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

(2010) M. Kowanetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

(2009) Zvi G. Fridlender et al.   CANCER CELL

Presence of Intratumoral Neutrophils Is an Independent Prognostic Factor in Localized Renal Cell Carcinoma

(2009) Hanne Krogh Jensen et al.   JOURNAL OF CLINICAL ONCOLOGY

Prognostic Factors for Overall Survival in Patients With Metastatic Renal Cell Carcinoma Treated With Vascular Endothelial Growth Factor–Targeted Agents: Results From a Large, Multicenter Study

(2009) Daniel Y.C. Heng et al.   JOURNAL OF CLINICAL ONCOLOGY

Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression

(2008) F. Shojaei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA