Conformational heterogeneity in tails of DNA-binding proteins is augmented by proline containing repeats

Structural and evolutionary analyses reveal determinants of DNA binding specificities of nucleoid-associated proteins HU and IHF

(2017) Debayan Dey et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

(2017) Michiru Nishita et al.   Scientific Reports

The contribution of intrinsically disordered regions to protein function, cellular complexity, and human disease

(2016) M. Madan Babu   BIOCHEMICAL SOCIETY TRANSACTIONS

The Role of Protein Loops and Linkers in Conformational Dynamics and Allostery

(2016) Elena Papaleo et al.   CHEMICAL REVIEWS

Lysine acetylation of theMycobacterium tuberculosisHU protein modulates its DNA binding and genome organization

(2016) Soumitra Ghosh et al.   MOLECULAR MICROBIOLOGY

Structural and thermodynamic basis of proline-induced transmembrane complex stabilization

(2016) Thomas Schmidt et al.   Scientific Reports

Backbone Hydration Determines the Folding Signature of Amino Acid Residues

(2015) Olivier Bignucolo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Histones and DNA Compete for Binding Polyphosphoinositides in Bilayers

(2014) Marta G. Lete et al.   BIOPHYSICAL JOURNAL

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

Intrinsic disorder as a generalizable strategy for the rational design of highly responsive, allosterically cooperative receptors

(2014) Anna J. Simon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct circular dichroism spectroscopic signatures of polyproline II and unordered secondary structures: Applications in secondary structure analyses

(2014) Jose L. S. Lopes et al.   PROTEIN SCIENCE

Elastin-like polypeptides as a promising family of genetically-engineered protein based polymers

(2014) Tomasz Kowalczyk et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors

(2014) Tuhin Bhowmick et al.   Nature Communications

Promiscuity as a functional trait: intrinsically disordered regions as central players of interactomes

(2013) Alexander Cumberworth et al.   BIOCHEMICAL JOURNAL

Contribution of proline to the pre-structuring tendency of transient helical secondary structure elements in intrinsically disordered proteins

(2013) Chewook Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

(2013) Daniel R. Roe et al.   Journal of Chemical Theory and Computation

Polyproline-II Helix in Proteins: Structure and Function

(2013) Alexei A. Adzhubei et al.   JOURNAL OF MOLECULAR BIOLOGY

Water–Peptide Dynamics during Conformational Transitions

(2013) Dmitry Nerukh et al.   Journal of Physical Chemistry Letters

Evolutionary conservation of the polyproline II conformation surrounding intrinsically disordered phosphorylation sites

(2013) W. Austin Elam et al.   PROTEIN SCIENCE

C-terminal low-complexity sequence repeats ofMycobacterium smegmatisKu modulate DNA binding

(2012) Ambuj K. Kushwaha et al.   BIOSCIENCE REPORTS

Dissecting the role of low-complexity regions in the evolution of vertebrate proteins

(2012) Núria Radó-Trilla et al.   BMC EVOLUTIONARY BIOLOGY

Understanding Pre-Structured Motifs (PreSMos) in Intrinsically Unfolded Proteins

(2012) Si-Hyung Lee et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Backbone conformational preferences of an intrinsically disordered protein in solution

(2012) L. Michel Espinoza-Fonseca et al.   Molecular BioSystems

Chemical composition is maintained in poorly conserved intrinsically disordered regions and suggests a means for their classification

(2012) Harry Amri Moesa et al.   Molecular BioSystems

Readers of histone modifications

(2011) Miyong Yun et al.   CELL RESEARCH

Evolution and disorder

(2011) Celeste J Brown et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Intrinsically disordered regions as affinity tuners in protein–DNA interactions

(2011) Dana Vuzman et al.   Molecular BioSystems

Assignment of PolyProline II Conformation and Analysis of Sequence – Structure Relationship

(2011) Yohann Mansiaux et al.   PLoS One

Dynamic protein–DNA recognition: beyond what can be seen

(2011) Monika Fuxreiter et al.   TRENDS IN BIOCHEMICAL SCIENCES

Bringing order to protein disorder through comparative genomics and genetic interactions

(2011) Jeremy Bellay et al.   GENOME BIOLOGY

CD-HIT Suite: a web server for clustering and comparing biological sequences

(2010) Ying Huang et al.   BIOINFORMATICS

Sequence Determinants of Compaction in Intrinsically Disordered Proteins

(2010) Joseph A. Marsh et al.   BIOPHYSICAL JOURNAL

Low-complexity regions within protein sequences have position-dependent roles

(2010) Alain Coletta et al.   BMC Systems Biology

Protein tandem repeats - the more perfect, the less structured

(2010) Julien Jorda et al.   FEBS Journal

β-Turn propensities as paradigms for the analysis of structural motifs to engineer protein stability

(2010) Ettore C. Ohage et al.   PROTEIN SCIENCE

T-REKS: identification of Tandem REpeats in sequences with a K-meanS based algorithm

(2009) Julien Jorda et al.   BIOINFORMATICS

Heparin-binding hemagglutinin (HBHA) ofMycobacterium lepraeis expressed during infection and enhances bacterial adherence to epithelial cells

(2009) Cristiana Soares de Lima et al.   FEMS MICROBIOLOGY LETTERS

One of the Two Genes Encoding Nucleoid-Associated HU Proteins in Streptomyces coelicolor Is Developmentally Regulated and Specifically Involved in Spore Maturation

(2009) P. Salerno et al.   JOURNAL OF BACTERIOLOGY

Searching DNA via a “Monkey Bar” Mechanism: The Significance of Disordered Tails

(2009) Dana Vuzman et al.   JOURNAL OF MOLECULAR BIOLOGY

How a protein searches for its site on DNA: the mechanism of facilitated diffusion

(2009) Leonid Mirny et al.   Journal of Physics A-Mathematical and Theoretical

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Increasing protein stability by improving beta-turns

(2009) Hailong Fu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The C-Terminal Domain of HU-Related Histone-like Protein Hlp fromMycobacterium smegmatisMediates DNA End-Joining†

(2008) Anirban Mukherjee et al.   BIOCHEMISTRY

Function and structure of inherently disordered proteins

(2008) A Keith Dunker et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Another role of proline: stabilization interactions in proteins and protein complexes concerning proline and tryptophane

(2008) Lada Biedermannova et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases

(2007) Lee Whitmore et al.   BIOPOLYMERS