CARMIL family proteins as multidomain regulators of actin-based motility

A human immunodeficiency syndrome caused by mutations in CARMIL2

(2017) T. Schober et al.   Nature Communications

Complex regulation of ADAR-mediated RNA-editing across tissues

(2016) Melanie A. Huntley et al.   BMC GENOMICS

In silico prediction of long intergenic non-coding RNAs in sheep

(2016) Mohammad Reza Bakhtiarizadeh et al.   GENOME

Regulators of actin filament barbed ends at a glance

(2016) Shashank Shekhar et al.   JOURNAL OF CELL SCIENCE

The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells

(2016) Romain Roncagalli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dual T cell– and B cell–intrinsic deficiency in humans with biallelicRLTPRmutations

(2016) Yi Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

V-1 regulates capping protein activity in vivo

(2016) Goeh Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin and Actin-Binding Proteins

(2016) Thomas D. Pollard   Cold Spring Harbor Perspectives in Biology

A potential founder variant inCARMIL2/RLTPRin three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction

(2016) Hanne S. Sorte et al.   Molecular Genetics & Genomic Medicine

Platelet Count Mediates the Contribution of a Genetic Variant in LRRC 16A to ARDS Risk

(2015) Yongyue Wei et al.   CHEST

Differential expression of CARMIL-family genes during zebrafish development

(2015) Benjamin C. Stark et al.   Cytoskeleton

Polarized Rac-dependent protrusions drive epithelial intercalation in the embryonic epidermis ofC. elegans

(2015) Elise Walck-Shannon et al.   DEVELOPMENT

Cell Migration and Invadopodia Formation Require a Membrane-binding Domain of CARMIL2

(2015) M. Hunter Lanier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CARMIL2 is a novel molecular connection between vimentin and actin essential for cell migration and invadopodia formation

(2015) M. Hunter Lanier et al.   MOLECULAR BIOLOGY OF THE CELL

Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor

(2015) Ruijun Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

CPI motif interaction is necessary for capping protein function in cells

(2015) Marc Edwards et al.   Nature Communications

Single-molecule visualization of a formin-capping protein ‘decision complex’ at the actin filament barbed end

(2015) Jeffrey P. Bombardier et al.   Nature Communications

Formin and capping protein together embrace the actin filament in a ménage à trois

(2015) Shashank Shekhar et al.   Nature Communications

A promoter-level mammalian expression atlas

(2014)   NATURE

Capping protein regulators fine-tune actin assembly dynamics

(2014) Marc Edwards et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Capping protein regulatory cycle driven by CARMIL and V-1 may promote actin network assembly at protruding edges

(2014) I. Fujiwara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Capping motifs stabilize the leucine-rich repeat protein PP32 and rigidify adjacent repeats

(2014) Thuy P. Dao et al.   PROTEIN SCIENCE

TNF-induced endothelial barrier disruption: beyond actin and Rho

(2014) Beatriz Marcos-Ramiro et al.   THROMBOSIS AND HAEMOSTASIS

Physical break-down of the classical view on cancer cell invasion and metastasis

(2013) Claudia T. Mierke   EUROPEAN JOURNAL OF CELL BIOLOGY

Formins at a glance

(2013) Dennis Breitsprecher et al.   JOURNAL OF CELL SCIENCE

Physiological role of the interaction between CARMIL1 and capping protein

(2013) Marc Edwards et al.   MOLECULAR BIOLOGY OF THE CELL

The lymphoid lineage–specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells

(2013) Yinming Liang et al.   NATURE IMMUNOLOGY

Expression Atlas update—a database of gene and transcript expression from microarray- and sequencing-based functional genomics experiments

(2013) Robert Petryszak et al.   NUCLEIC ACIDS RESEARCH

Neonicotinoid clothianidin adversely affects insect immunity and promotes replication of a viral pathogen in honey bees

(2013) G. Di Prisco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CARMIL leading edge localization depends on a non-canonical PH domain and dimerization

(2013) Adam Zwolak et al.   Nature Communications

A common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility

(2013) Masayuki Sakiyama et al.   Human Cell

Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation

(2013) P. Gupta et al.   Biology Open

Mechanism for CARMIL Protein Inhibition of Heterodimeric Actin-capping Protein

(2012) Taekyung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CD2AP Links Cortactin and Capping Protein at the Cell Periphery To Facilitate Formation of Lamellipodia

(2012) J. Zhao et al.   MOLECULAR AND CELLULAR BIOLOGY

A versatile gene trap to visualize and interrogate the function of the vertebrate proteome

(2011) L. A. Trinh et al.   GENES & DEVELOPMENT

Gene Expression Atlas update--a value-added database of microarray and sequencing-based functional genomics experiments

(2011) M. Kapushesky et al.   NUCLEIC ACIDS RESEARCH

Molecular Basis for Barbed End Uncapping by CARMIL Homology Domain 3 of Mouse CARMIL-1

(2010) Adam Zwolak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Capping Protein Sequestration by Myotrophin (V-1)

(2010) Adam Zwolak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Interaction of Capping Protein with the Barbed End of the Actin Filament

(2010) Taekyung Kim et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural characterization of a capping protein interaction motif defines a family of actin filament regulators

(2010) Maria Hernandez-Valladares et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identifying LRRC16B as an oncofetal gene with transforming enhancing capability using a combined bioinformatics and experimental approach

(2010) C-C Hsu et al.   ONCOGENE

Two Distinct Mechanisms for Actin Capping Protein Regulation—Steric and Allosteric Inhibition

(2010) Shuichi Takeda et al.   PLOS BIOLOGY

Mechanics, malignancy, and metastasis: The force journey of a tumor cell

(2009) Sanjay Kumar et al.   CANCER AND METASTASIS REVIEWS

C. elegans CARMIL negatively regulates UNC-73/Trio function during neuronal development

(2009) P. J. Vanderzalm et al.   DEVELOPMENT

Direct Observation of the Uncapping of Capping Protein-capped Actin Filaments by CARMIL Homology Domain 3

(2009) Ikuko Fujiwara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Experimentally Based Computer Search Identifies Unstructured Membrane-binding Sites in Proteins

(2009) Hanna Brzeska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Roles for CARMIL Isoforms in Cell Migration

(2009) Yun Liang et al.   MOLECULAR BIOLOGY OF THE CELL

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE

Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations

(2009) Melanie Kolz et al.   PLoS Genetics

The leucine-rich repeat structure

(2008) J. Bella et al.   CELLULAR AND MOLECULAR LIFE SCIENCES