Regulators of actin filament barbed ends at a glance

Profilin Interaction with Actin Filament Barbed End Controls Dynamic Instability, Capping, Branching, and Motility

(2016) Julien Pernier et al.   DEVELOPMENTAL CELL

Single-filament kinetic studies provide novel insights into regulation of actin-based motility

(2016) Shashank Shekhar et al.   MOLECULAR BIOLOGY OF THE CELL

Control of polarized assembly of actin filaments in cell motility

(2015) Marie-France Carlier et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Architecture Dependence of Actin Filament Network Disassembly

(2015) Laurène Gressin et al.   CURRENT BIOLOGY

The Arp2/3 inhibitory protein arpin induces cell turning by pausing cell migration

(2015) Roman Gorelik et al.   Cytoskeleton

Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways

(2015) Jeremy D. Rotty et al.   DEVELOPMENTAL CELL

Profilin Regulates F-Actin Network Homeostasis by Favoring Formin over Arp2/3 Complex

(2015) Cristian Suarez et al.   DEVELOPMENTAL CELL

Role of the C-terminal Extension of Formin 2 in Its Activation by Spire Protein and Processive Assembly of Actin Filaments

(2015) Pierre Montaville et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coronin Enhances Actin Filament Severing by Recruiting Cofilin to Filament Sides and Altering F-Actin Conformation

(2015) Mouna A. Mikati et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif

(2015) Eunyoung Park et al.   STRUCTURE

CPI motif interaction is necessary for capping protein function in cells

(2015) Marc Edwards et al.   Nature Communications

Single-molecule visualization of a formin-capping protein ‘decision complex’ at the actin filament barbed end

(2015) Jeffrey P. Bombardier et al.   Nature Communications

Formin and capping protein together embrace the actin filament in a ménage à trois

(2015) Shashank Shekhar et al.   Nature Communications

Arp2/3-mediated F-actin formation controls regulated exocytosis in vivo

(2015) Duy T. Tran et al.   Nature Communications

Aip1 Destabilizes Cofilin-Saturated Actin Filaments by Severing and Accelerating Monomer Dissociation from Ends

(2014) Ambika V. Nadkarni et al.   CURRENT BIOLOGY

Saccharomyces cerevisiaeKelch Proteins and Bud14 Protein Form a Stable 520-kDa Formin Regulatory Complex That Controls Actin Cable Assembly and Cell Morphogenesis

(2014) Christopher J. Gould et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Formin Tails in Actin Nucleation, Processive Elongation, and Filament Bundling

(2014) Christina L. Vizcarra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Capping protein is essential for cell migration in vivo and for filopodial morphology and dynamics

(2014) Shamim A. Sinnar et al.   MOLECULAR BIOLOGY OF THE CELL

Capping protein regulators fine-tune actin assembly dynamics

(2014) Marc Edwards et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A High-Content, Multiplexed Screen in Human Breast Cancer Cells Identifies Profilin-1 Inducers with Anti-Migratory Activities

(2014) Marion E. Joy et al.   PLoS One

Capping protein regulatory cycle driven by CARMIL and V-1 may promote actin network assembly at protruding edges

(2014) I. Fujiwara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spire and Formin 2 Synergize and Antagonize in Regulating Actin Assembly in Meiosis by a Ping-Pong Mechanism

(2014) Pierre Montaville et al.   PLOS BIOLOGY

Electron Tomography and Simulation of Baculovirus Actin Comet Tails Support a Tethered Filament Model of Pathogen Propulsion

(2014) Jan Mueller et al.   PLOS BIOLOGY

Small Molecules CK-666 and CK-869 Inhibit Actin-Related Protein 2/3 Complex by Blocking an Activating Conformational Change

(2013) Byron Hetrick et al.   CHEMISTRY & BIOLOGY

Gelsolin: The tail of a molecular gymnast

(2013) Shalini Nag et al.   Cytoskeleton

Guardians of the actin monomer

(2013) Bo Xue et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Ligand-induced activation of a formin–NPF pair leads to collaborative actin nucleation

(2013) Brian R. Graziano et al.   JOURNAL OF CELL BIOLOGY

Dimeric WH2 domains in Vibrio VopF promote actin filament barbed-end uncapping and assisted elongation

(2013) Julien Pernier et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pathway of actin filament branch formation by Arp2/3 complex revealed by single-molecule imaging

(2013) Benjamin A. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tension modulates actin filament polymerization mediated by formin and profilin

(2013) N. Courtemanche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formin mDia1 senses and generates mechanical forces on actin filaments

(2013) Antoine Jégou et al.   Nature Communications

Roles for Actin Assembly in Endocytosis

(2012) Olivia L. Mooren et al.   Annual Review of Biochemistry

New insights into the regulation and cellular functions of the ARP2/3 complex

(2012) Jeremy D. Rotty et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex

(2012) T. Maritzen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rocket Launcher Mechanism of Collaborative Actin Assembly Defined by Single-Molecule Imaging

(2012) D. Breitsprecher et al.   SCIENCE

Spire-Type Actin Nucleators Cooperate with Formin-2 to Drive Asymmetric Oocyte Division

(2011) Sybille Pfender et al.   CURRENT BIOLOGY

Structural Organization of the Actin Cytoskeleton at Sites of Clathrin-Mediated Endocytosis

(2011) Agnieszka Collins et al.   CURRENT BIOLOGY

The Myosin Passenger Protein Smy1 Controls Actin Cable Structure and Dynamics by Acting as a Formin Damper

(2011) Melissa Chesarone-Cataldo et al.   DEVELOPMENTAL CELL

The C Terminus of Formin FMNL3 Accelerates Actin Polymerization and Contains a WH2 Domain-like Sequence That Binds Both Monomers and Filament Barbed Ends

(2011) Ernest G. Heimsath et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis of Actin Nucleation Factor Cooperativity

(2011) Kornelius Zeth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and function of the interacting domains of Spire and Fmn-family formins

(2011) C. L. Vizcarra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Individual Actin Filaments in a Microfluidic Flow Reveal the Mechanism of ATP Hydrolysis and Give Insight Into the Properties of Profilin

(2011) Antoine Jégou et al.   PLOS BIOLOGY

Control of Actin Filament Treadmilling in Cell Motility

(2010) Beáta Bugyi et al.   Annual Review of Biophysics

Structural Basis for Capping Protein Sequestration by Myotrophin (V-1)

(2010) Adam Zwolak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adenomatous polyposis coli protein nucleates actin assembly and synergizes with the formin mDia1

(2010) Kyoko Okada et al.   JOURNAL OF CELL BIOLOGY

Two Distinct Mechanisms for Actin Capping Protein Regulation—Steric and Allosteric Inhibition

(2010) Shuichi Takeda et al.   PLOS BIOLOGY

Displacement of Formins from Growing Barbed Ends by Bud14 Is Critical for Actin Cable Architecture and Function

(2009) Melissa Chesarone et al.   DEVELOPMENTAL CELL

Direct Observation of the Uncapping of Capping Protein-capped Actin Filaments by CARMIL Homology Domain 3

(2009) Ikuko Fujiwara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers

(2008) Hao Yuan Kueh et al.   JOURNAL OF CELL BIOLOGY