Engineered biosynthesis of milbemycins in the avermectin high-producing strain Streptomyces avermitilis

Gene Replacement for the Generation of Designed Novel Avermectin Derivatives with Enhanced Acaricidal and Nematicidal Activities

(2015) Jun Huang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Reinvigorating natural product combinatorial biosynthesis with synthetic biology

(2015) Eunji Kim et al.   Nature Chemical Biology

Recent advances in biochemistry and biotechnological synthesis of avermectins and their derivatives

(2014) Nguyen Huy Thuan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genetic engineering of Streptomyces bingchenggensis to produce milbemycins A3/A4 as main components and eliminate the biosynthesis of nanchangmycin

(2013) Ji Zhang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Spiroketal Formation and Modification in Avermectin Biosynthesis Involves a Dual Activity of AveC

(2013) Peng Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineered Streptomyces avermitilis Host for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites

(2013) Mamoru Komatsu et al.   ACS Synthetic Biology

A Review on the Toxicity and Non-Target Effects of Macrocyclic Lactones in Terrestrial and Aquatic Environments

(2012) Jean-Pierre Lumaret et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Cloning of Separate Meilingmycin Biosynthesis Gene Clusters by Use of Acyltransferase-Ketoreductase Didomain PCR Amplification

(2010) Y. He et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genome Sequence of the Milbemycin-Producing Bacterium Streptomyces bingchenggensis

(2010) X.-J. Wang et al.   JOURNAL OF BACTERIOLOGY

Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase

(2010) S. Kapur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

(2010) M. Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New Seco-milbemycins from Streptomyces bingchenggensis: Fermentation, Isolation and Structure Elucidation

(2009) Wen-Sheng Xiang et al.   JOURNAL OF ANTIBIOTICS

High titer production of tetracenomycins by heterologous expression of the pathway in a Streptomyces cinnamonensis industrial monensin producer strain

(2009) Chaoxuan Li et al.   METABOLIC ENGINEERING

Improvement of milbemycin-producing Streptomyces bingchenggensis by rational screening of ultraviolet- and chemically induced mutants

(2009) Xiang-Jing Wang et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY