The cytochrome b5 CybE is regulated by iron availability and is crucial for azole resistance in A. fumigatus

Comparison of xenobiotic-metabolising human, porcine, rodent, and piscine cytochrome P450

(2017) Viktoriia Burkina et al.   TOXICOLOGY

Heterogeneity Confounds Establishment of “a” Model Microbial Strain

(2017) Nancy P. Keller   mBio

Executive Summary: Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America

(2016) Thomas F. Patterson et al.   CLINICAL INFECTIOUS DISEASES

Versatile biocatalysis of fungal cytochrome P450 monooxygenases

(2016) Pradeepraj Durairaj et al.   Microbial Cell Factories

Heterogeneity among Isolates Reveals that Fitness in Low Oxygen Correlates with Aspergillus fumigatus Virulence

(2016) Caitlin H. Kowalski et al.   mBio

Aspergillus fumigatus Photobiology Illuminates the Marked Heterogeneity between Isolates

(2016) Kevin K. Fuller et al.   mBio

Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex

(2016) Fabio Gsaller et al.   PLoS Pathogens

An Antifungal Benzimidazole Derivative Inhibits Ergosterol Biosynthesis and Reveals Novel Sterols

(2015) Petra Keller et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroBiochemical Study of CYP51-Mediated Azole Resistance in Aspergillus fumigatus

(2015) Andrew G. S. Warrilow et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Electron Transfer Pathways in Cholesterol Synthesis

(2015) Todd D. Porter   LIPIDS

Determination by GC-IT/MS of Phytosterols in Herbal Medicinal Products for the Treatment of Lower Urinary Tract Symptoms and Food Products Marketed in Europe

(2015) Christoph Müller et al.   PLANTA MEDICA

Current status of antifungal resistance and its impact on clinical practice

(2014) Laura Alcazar-Fuoli et al.   BRITISH JOURNAL OF HAEMATOLOGY

The Janus transcription factor HapX controls fungal adaptation to both iron starvation and iron excess

(2014) F. Gsaller et al.   EMBO JOURNAL

ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence

(2014) Dawoon Chung et al.   PLoS Pathogens

Therapies for the treatment of onychomycosis

(2013) Aditya K. Gupta et al.   CLINICS IN DERMATOLOGY

The cdr1B efflux transporter is associated with non-cyp51a-mediated itraconazole resistance in Aspergillus fumigatus 

(2013) Marcin G. Fraczek et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A convenient cellular assay for the identification of the molecular target of ergosterol biosynthesis inhibitors and quantification of their effects on total ergosterol biosynthesis

(2013) Christoph Müller et al.   STEROIDS

Aspergillus fumigatus—What Makes the Species a Ubiquitous Human Fungal Pathogen?

(2013) Kyung J. Kwon-Chung et al.   PLoS Pathogens

Activation of the neutrophil NADPH oxidase byAspergillus fumigatus

(2012) Keith B. Boyle et al.   Annals of the New York Academy of Sciences

Hypoxia and Fungal Pathogenesis: To Air or Not To Air?

(2012) Nora Grahl et al.   EUKARYOTIC CELL

High-level expression of cyp51B in azole-resistant clinical Aspergillus fumigatus isolates

(2012) A. Buied et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The interplay between vacuolar and siderophore-mediated iron storage in Aspergillus fumigatus

(2012) Fabio Gsaller et al.   Metallomics

Diversity of P450 enzymes in the biosynthesis of natural products

(2012) Larissa M. Podust et al.   NATURAL PRODUCT REPORTS

Iron – A Key Nexus in the Virulence of Aspergillus fumigatus

(2012) Hubertus Haas   Frontiers in Microbiology

SREBP-Dependent Triazole Susceptibility in Aspergillus fumigatus Is Mediated through Direct Transcriptional Regulation oferg11A(cyp51A)

(2011) Sara J. Blosser et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Iron homeostasis—Achilles’ heel of Aspergillus fumigatus?

(2011) Markus Schrettl et al.   CURRENT OPINION IN MICROBIOLOGY

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

(2011) Michael Blatzer et al.   PLoS Genetics

Validation of a Self-Excising Marker in the Human Pathogen Aspergillus fumigatus by Employing the  -Rec/six Site-Specific Recombination System

(2010) T. Hartmann et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Sterol Regulatory Element Binding Proteins in Fungi: Hypoxic Transcription Factors Linked to Pathogenesis

(2010) Clara M. Bien et al.   EUKARYOTIC CELL

HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus

(2010) Markus Schrettl et al.   PLoS Pathogens

Special relationship between sterols and oxygen: Were sterols an adaptation to aerobic life?

(2009) Anne M. Galea et al.   FREE RADICAL BIOLOGY AND MEDICINE

Fungal cytochrome P450 database

(2008) Jongsun Park et al.   BMC GENOMICS

Treatment of Aspergillosis: Clinical Practice Guidelines of the Infectious Diseases Society of America

(2008) Thomas J. Walsh et al.   CLINICAL INFECTIOUS DISEASES

Ergosterol biosynthesis pathway in Aspergillus fumigatus

(2007) Laura Alcazar-Fuoli et al.   STEROIDS