Progress in the synthesis and biological evaluation of lipid A and its derivatives

A Semisynthetic Approach to New Immunoadjuvant Candidates: Site-Selective Chemical Manipulation of Escherichia coli Monophosphoryl Lipid A

(2016) Daniele D'Alonzo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fully Synthetic Self-Adjuvanting α-2,9-Oligosialic Acid Based Conjugate Vaccines against Group C Meningitis

(2016) Guochao Liao et al.   ACS Central Science

Synthesis and immunological study of α-2,9-oligosialic acid conjugates as anti-group C meningitis vaccines

(2015) Guochao Liao et al.   CHEMICAL COMMUNICATIONS

Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate ofBurkholderia cenocepacia

(2015) Flaviana Di Lorenzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A fully synthetic self-adjuvanting globo H-Based vaccine elicited strong T cell-mediated antitumor immunity

(2015) Zhifang Zhou et al.   Chemical Science

O-antigen polymerase adopts a distributive mechanism for lipopolysaccharide biosynthesis

(2014) Guohui Zhao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Chemistry of Lipid A: At the Heart of Innate Immunity

(2014) Antonio Molinaro et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis and evaluation of monophosphoryl lipid A derivatives as fully synthetic self-adjuvanting glycoconjugate cancer vaccine carriers

(2014) Zhifang Zhou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and immunomodulatory activities of Helicobacter pylori lipophilic terminus of lipopolysaccharide including lipid A

(2012) Yukari Fujimoto et al.   CARBOHYDRATE RESEARCH

Sweet carbon nanostructures: carbohydrate conjugates with carbon nanotubes and graphene and their applications

(2012) Yanan Chen et al.   CHEMICAL SOCIETY REVIEWS

Carbohydrate-Monophosphoryl Lipid A Conjugates Are Fully Synthetic Self-Adjuvanting Cancer Vaccines Eliciting Robust Immune Responses in the Mouse

(2011) Qianli Wang et al.   ACS Chemical Biology

Chemical Synthesis of Helicobacter pylori Lipopolysaccharide Partial Structures and their Selective Proinflammatory Responses

(2011) Atsushi Shimoyama et al.   CHEMISTRY-A EUROPEAN JOURNAL

Eritoran tetrasodium (E5564) treatment for sepsis: review of preclinical and clinical studies

(2011) Amisha Barochia et al.   Expert Opinion on Drug Metabolism & Toxicology

Defining Function of Lipopolysaccharide O-antigen Ligase WaaL Using Chemoenzymatically Synthesized Substrates

(2011) Weiqing Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of LPS antagonistic therapeutics: synthesis and evaluation of glucopyranoside-spacer-amino acid motifs

(2011) Sophon Kaeothip et al.   RSC Advances

Fully Synthetic Vaccines Consisting of Tumor-Associated MUC1 Glycopeptides and a Lipopeptide Ligand of the Toll-like Receptor 2

(2010) Anton Kaiser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Differential Induction of Innate Immune Responses by Synthetic Lipid A Derivatives

(2010) Jidnyasa Gaekwad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vitro bacterial polysaccharide biosynthesis: defining the functions of Wzy and Wzz

(2010) Robert Woodward et al.   Nature Chemical Biology

Synthesis of a monophosphoryl lipid A derivative and its conjugation to a modified form of a tumor-associated carbohydrate antigen GM3

(2009) Qianli Wang et al.   CHEMICAL COMMUNICATIONS

Synthesis of a Monophosphoryl Derivative ofEscherichia coliLipid A and Its Efficient Coupling to a Tumor-Associated Carbohydrate Antigen

(2009) Shouchu Tang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent development in carbohydrate-based cancer vaccines

(2009) Zhongwu Guo et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chemical Synthesis and Proinflammatory Responses of Monophosphoryl Lipid A Adjuvant Candidates

(2009) Kaustabh K. Maiti et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Lipopolysaccharide: Biosynthetic pathway and structure modification

(2009) Xiaoyuan Wang et al.   PROGRESS IN LIPID RESEARCH

Synthesis ofRubrivivax gelatinosusLipid A and Analogues for Investigation of the Structural Basis for Immunostimulating and Inhibitory Activities

(2008) Yoshiyuki Fukase et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant

(2008) C. R. Casella et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The structure and proinflammatory activity of the lipopolysaccharide from Burkholderia multivorans and the differences between clonal strains colonizing pre and posttransplanted lungs

(2008) Teresa Ieranò et al.   GLYCOBIOLOGY

Synthetic tetra-acylated derivatives of lipid A from Porphyromonas gingivalis are antagonists of human TLR4

(2008) Yanghui Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY