A Semisynthetic Approach to New Immunoadjuvant Candidates: Site-Selective Chemical Manipulation of Escherichia coli Monophosphoryl Lipid A

Chemical Fucosylation of a Polysaccharide: A Semisynthetic Access to Fucosylated Chondroitin Sulfate

(2015) Antonio Laezza et al.   BIOMACROMOLECULES

A fully synthetic self-adjuvanting globo H-Based vaccine elicited strong T cell-mediated antitumor immunity

(2015) Zhifang Zhou et al.   Chemical Science

A combined fermentative-chemical approach for the scalable production of pure E. coli monophosphoryl lipid A

(2014) Giuseppina Pieretti et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Chemistry of Lipid A: At the Heart of Innate Immunity

(2014) Antonio Molinaro et al.   CHEMISTRY-A EUROPEAN JOURNAL

NKT-cell adjuvants in conjugate

(2014) Paul B Savage   Nature Chemical Biology

A self-adjuvanting vaccine induces cytotoxic T lymphocytes that suppress allergy

(2014) Regan J Anderson et al.   Nature Chemical Biology

Synthesis and evaluation of monophosphoryl lipid A derivatives as fully synthetic self-adjuvanting glycoconjugate cancer vaccine carriers

(2014) Zhifang Zhou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Zwitterionic 1,1′-Glycosylphosphodiester: A Partial Structure of Galactosamine-Modified Francisella Lipid A

(2014) David Baum et al.   ORGANIC LETTERS

Direct Peptide Lipidation through Thiol-Ene Coupling Enables Rapid Synthesis and Evaluation of Self-Adjuvanting Vaccine Candidates

(2013) Tom H. Wright et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Tailoring of Teicoplanin with Site-Selective Reactions

(2013) Tejas P. Pathak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Influence of Lipid A Acylation Pattern on Membrane Permeability and Innate Immune Stimulation

(2013) Yanyan Li et al.   Marine Drugs

Sequential 1,4- and 1,2-Addition Reactions to α,β-Unsaturated N-Acyliminium Ions: A New Strategy for the Synthesis of Spiro and Bridged Heterocycles

(2013) Arife Yazici et al.   ORGANIC LETTERS

Modulating the innate immune response by combinatorial engineering of endotoxin

(2013) Brittany D. Needham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The development of N-aryl trifluoroacetimidate-based benzyl and allyl protecting group reagents

(2013) Sinele B. Tsabedze et al.   TETRAHEDRON LETTERS

Fully Synthetic Self-Adjuvanting Thioether-Conjugated GlycopeptideLipopeptide Antitumor Vaccines for the Induction of Complement-Dependent Cytotoxicity against Tumor Cells

(2012) Hui Cai et al.   CHEMISTRY-A EUROPEAN JOURNAL

Semi-Synthesis of Unusual Chondroitin Sulfate Polysaccharides Containing GlcA(3-O-sulfate) or GlcA(2,3-di-O-sulfate) Units

(2012) Emiliano Bedini et al.   CHEMISTRY-A EUROPEAN JOURNAL

Facile Synthesis of a Library of Lyme Disease Glycolipid Antigens

(2012) Jean-d’Amour K. Twibanire et al.   ORGANIC LETTERS

A Microbiological-Chemical Strategy to Produce Chondroitin Sulfate A,C

(2011) Emiliano Bedini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bifunctional Dendronized Cellulose Surfaces as Biosensors

(2011) Maria I. Montañez et al.   BIOMACROMOLECULES

Chemical Synthesis of Helicobacter pylori Lipopolysaccharide Partial Structures and their Selective Proinflammatory Responses

(2011) Atsushi Shimoyama et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structural Investigation and Biological Activity of the Lipooligosaccharide from the Psychrophilic Bacterium Pseudoalteromonas haloplanktis TAB 23

(2011) Sara Carillo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cytokines: The Future of Intranasal Vaccine Adjuvants

(2011) Afton L. Thompson et al.   Clinical & Developmental Immunology

Outlining novel cellular adjuvant products for therapeutic vaccines against cancer

(2011) Josianne Nitcheu Tefit et al.   Expert Review of Vaccines

Organoiodine(V) Reagents in Organic Synthesis

(2011) Viktor V. Zhdankin   JOURNAL OF ORGANIC CHEMISTRY

High cell density cultivation of Escherichia coli K4 in a microfiltration bioreactor: a step towards improvement of chondroitin precursor production

(2011) Odile Restaino et al.   Microbial Cell Factories

The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ

(2011) Feng Ma et al.   NATURE IMMUNOLOGY

Efficient and Controllably Selective Preparation of Esters Using Uronium-Based Coupling Agents

(2011) Jean-d’Amour K. Twibanire et al.   ORGANIC LETTERS

Development and Characterization of Synthetic Glucopyranosyl Lipid Adjuvant System as a Vaccine Adjuvant

(2011) Rhea N. Coler et al.   PLoS One

A new rapid and micro-scale hydrolysis, using triethylamine citrate, for lipopolysaccharide characterization by mass spectrometry

(2011) Imane Chafchaouni-Moussaoui et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Perfectly regioselective acylation of a cardiac glycoside, digitoxin, via catalytic amplification of the intrinsic reactivity

(2010) Keisuke Yoshida et al.   TETRAHEDRON LETTERS

A New Ligation Strategy for Peptide and Protein Glycosylation: Photoinduced Thiol-Ene Coupling

(2009) Alessandro Dondoni et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of a Monophosphoryl Derivative ofEscherichia coliLipid A and Its Efficient Coupling to a Tumor-Associated Carbohydrate Antigen

(2009) Shouchu Tang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Chemical Synthesis and Proinflammatory Responses of Monophosphoryl Lipid A Adjuvant Candidates

(2009) Kaustabh K. Maiti et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Photoinduced Thiol−Ene Coupling as a Click Ligation Tool for Thiodisaccharide Synthesis

(2009) Michele Fiore et al.   JOURNAL OF ORGANIC CHEMISTRY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

The Emergence of Thiol-Ene Coupling as a Click Process for Materials and Bioorganic Chemistry

(2008) Alessandro Dondoni   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic TLR4-active Glycolipids as Vaccine Adjuvants and Stand-alone Immunotherapeutics

(2008) David Johnson   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Innate Immune Responses of Synthetic Lipid A Derivatives ofNeisseria meningitidis

(2007) Yanghui Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL