A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte

Recent progress on MAP kinase pathway inhibitors

(2015) David E. Uehling et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

Atrial natriuretic peptide down-regulates LPS/ATP-mediated IL-1β release by inhibiting NF-kB, NLRP3 inflammasome and caspase-1 activation in THP-1 cells

(2015) Letizia Mezzasoma et al.   IMMUNOLOGIC RESEARCH

Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function

(2014) M. G. Ghonime et al.   JOURNAL OF IMMUNOLOGY

Guanylyl cyclase/natriuretic peptide receptor-A signaling antagonizes phosphoinositide hydrolysis, Ca2+ release, and activation of protein kinase C

(2014) Kailash N. Pandey   Frontiers in Molecular Neuroscience

Bay11-7082 attenuates murine lupus nephritis via inhibiting NLRP3 inflammasome and NF-κB activation

(2013) Jijun Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TNF-αRegulates Natriuretic Peptides and Aquaporins in Human Bronchial Epithelial Cells BEAS-2B

(2013) Letizia Mezzasoma et al.   MEDIATORS OF INFLAMMATION

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

Attenuation of Monocyte Chemotaxis—A Novel Anti-inflammatory Mechanism of Action for the Cardio-protective Hormone B-Type Natriuretic Peptide

(2013) Nadezhda Glezeva et al.   Journal of Cardiovascular Translational Research

Mechanisms of disease: inflammasome activation and the development of type 2 diabetes

(2013) Ryan W. Grant et al.   Frontiers in Immunology

IκB kinase regulation of the TPL-2/ERK MAPK pathway

(2012) Thorsten Gantke et al.   IMMUNOLOGICAL REVIEWS

Inflammasomes in wound healing and fibrosis

(2012) Carol M Artlett   JOURNAL OF PATHOLOGY

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

(2011) P. Menu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines

(2011) Brianne R Barker et al.   CURRENT OPINION IN IMMUNOLOGY

The NLR Adaptor ASC/PYCARD Regulates DUSP10, Mitogen-activated Protein Kinase (MAPK), and Chemokine Induction Independent of the Inflammasome

(2011) Debra J. Taxman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammasome is a central player in the induction of obesity and insulin resistance

(2011) R. Stienstra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions

(2011) Y. Dombrowski et al.   Science Translational Medicine

Therapeutic effects of continuous infusion of brain natriuretic peptides on postmyocardial infarction ventricular remodelling in rats

(2010) Yesheng Pan et al.   Archives of Cardiovascular Diseases

Inflammasome-independent Role of Apoptosis-associated Speck-like Protein Containing a CARD (ASC) in T Cell Priming Is Critical for Collagen-induced Arthritis

(2010) Sirish K. Ippagunta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammasome signaling at the heart of central nervous system pathology

(2010) Swarupa Chakraborty et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β

(2009) Miyako Okamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Critical Role of Apoptotic Speck Protein Containing a Caspase Recruitment Domain (ASC) and NLRP3 in Causing Necrosis and ASC Speck Formation Induced by Porphyromonas gingivalis in Human Cells

(2009) M. T.-H. Huang et al.   JOURNAL OF IMMUNOLOGY

Molecular mechanisms involved in inflammasome activation

(2009) Clare Bryant et al.   TRENDS IN CELL BIOLOGY

The Interleukin 1β Pathway in the Pathogenesis of Osteoarthritis

(2008) Massoud Daheshia et al.   JOURNAL OF RHEUMATOLOGY

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

(2008) Alexandra-Chloé Villani et al.   NATURE GENETICS

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

Brain Natriuretic Peptide (BNP) regulates the production of inflammatory mediators in human THP-1 macrophages

(2008) V. Chiurchiù et al.   REGULATORY PEPTIDES