Efficacy of Low-Molecular-Weight Fucoidan as a Supplemental Therapy in Metastatic Colorectal Cancer Patients: A Double-Blind Randomized Controlled Trial

An Exploratory Study on the Anti-inflammatory Effects of Fucoidan in Relation to Quality of Life in Advanced Cancer Patients

(2017) Hidenori Takahashi et al.   INTEGRATIVE CANCER THERAPIES

A review about the development of fucoidan in antitumor activity: Progress and challenges

(2016) Lei Wu et al.   CARBOHYDRATE POLYMERS

Structural, antioxidant, and emulsifying activities of fucoidan from Saccharina japonica using pressurized liquid extraction

(2016) Periaswamy Sivagnanam Saravana et al.   CARBOHYDRATE POLYMERS

The Effect of Undaria pinnatifida Fucoidan on the Pharmacokinetics of Letrozole and Tamoxifen in Patients With Breast Cancer

(2016) Shreya Tocaciu et al.   INTEGRATIVE CANCER THERAPIES

Cytotoxic effect of fucoidan extracted from Sargassum cinereum on colon cancer cell line HCT-15

(2016) Sivasankara Narayani Somasundaram et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Mechanisms of resistance to anti-EGFR therapy in colorectal cancer

(2016) Ben Zhao et al.   Oncotarget

Mutations of KRAS/NRAS/BRAF predict cetuximab resistance in metastatic colorectal cancer patients

(2016) Hung-Chih Hsu et al.   Oncotarget

Low molecular weight fucoidan protects renal tubular cells from injury induced by albumin overload

(2016) Yingli Jia et al.   Scientific Reports

Low-molecular-weight fucoidan and high-stability fucoxanthin from brown seaweed exert prebiotics and anti-inflammatory activities in Caco-2 cells

(2016) Pai-An Hwang et al.   Food & Nutrition Research

Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis

(2016) Jingjing Li et al.   PLoS One

Microwave assisted extraction of sulfated polysaccharides (fucoidan) from Ascophyllum nodosum and its antioxidant activity

(2015) Yuan Yuan et al.   CARBOHYDRATE POLYMERS

Prophylactic Administration of Fucoidan Represses Cancer Metastasis by Inhibiting Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinases (MMPs) in Lewis Tumor-Bearing Mice

(2015) Tse-Hung Huang et al.   Marine Drugs

Fucoidan Elevates MicroRNA-29b to Regulate DNMT3B-MTSS1 Axis and Inhibit EMT in Human Hepatocellular Carcinoma Cells

(2015) Ming-De Yan et al.   Marine Drugs

Low Molecular Weight Fucoidan Inhibits Tumor Angiogenesis through Downregulation of HIF-1/VEGF Signaling under Hypoxia

(2015) Meng-Chuan Chen et al.   Marine Drugs

Fucoidan inhibits the migration and proliferation of HT-29 human colon cancer cells via the phosphoinositide-3 kinase/Akt/mechanistic target of rapamycin pathways

(2015) YONG-SEOK HAN et al.   Molecular Medicine Reports

Dietary fucoidan of Acaudina molpadioides and its enzymatically degraded fragments could prevent intestinal mucositis induced by chemotherapy in mice

(2015) Tao Zuo et al.   Food & Function

Fucoidan inhibition of lung cancer in vivo and in vitro : role of the Smurf2-dependent ubiquitin proteasome pathway in TGFβ receptor degradation

(2015) Hsien-Yeh Hsu et al.   Oncotarget

Ultrasound Effects on the Degradation Kinetics, Structure, and Antioxidant Activity of Sea Cucumber Fucoidan

(2014) Xin Guo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Anticancer Effects of Different Seaweeds on Human Colon and Breast Cancers

(2014) Ghislain Moussavou et al.   Marine Drugs

Fucoidan attenuates the existing allodynia and hyperalgesia in a rat model of neuropathic pain

(2014) Chuanyin Hu et al.   NEUROSCIENCE LETTERS

Hydrolysis of Fucoidan by Fucoidanase Isolated from the Marine Bacterium, Formosa algae

(2013) Artem Silchenko et al.   Marine Drugs

Fucoidan Extract Enhances the Anti-Cancer Activity of Chemotherapeutic Agents in MDA-MB-231 and MCF-7 Breast Cancer Cells

(2013) Zhongyuan Zhang et al.   Marine Drugs

Fucoidan induces changes in the epithelial to mesenchymal transition and decreases metastasis by enhancing ubiquitin-dependent TGF  receptor degradation in breast cancer

(2012) H.-Y. Hsu et al.   CARCINOGENESIS

Novel procedures for the extraction of fucoidan from brown algae

(2012) Thomas Hahn et al.   PROCESS BIOCHEMISTRY

Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer

(2011) MASAHIDE IKEGUCHI et al.   Oncology Letters

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

(2010) Wendy De Roock et al.   LANCET ONCOLOGY

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

(2008) E.A. Eisenhauer et al.   EUROPEAN JOURNAL OF CANCER

Fucoidan: Structure and Bioactivity

(2008) Bo Li et al.   MOLECULES

Antioxidant activity of sulfated polysaccharide fractions extracted from Laminaria japonica

(2007) Jing Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES