Hydrogen/deuterium exchange mass spectrometry and computational modeling reveal a discontinuous epitope of an antibody/TL1A Interaction

Directed evolution of a soluble human DR3 receptor for the inhibition of TL1A induced cytokine secretion

(2017) Itay Levin et al.   PLoS One

Application of amide hydrogen/deuterium exchange mass spectrometry for epitope mapping in human cystatin C

(2016) Martyna Prądzińska et al.   AMINO ACIDS

Biologics beyond TNF-αinhibitors and the effect of targeting the homologues TL1A-DR3 pathway in chronic inflammatory disorders

(2016) Peter Tougaard et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Antibody Structural Integrity of Site-Specific Antibody-Drug Conjugates Investigated by Hydrogen/Deuterium Exchange Mass Spectrometry

(2015) Lucy Yan Pan et al.   ANALYTICAL CHEMISTRY

Computational prediction of protein interfaces: A review of data driven methods

(2015) Li C. Xue et al.   FEBS LETTERS

Effects of Sucrose and Benzyl Alcohol on GCSF Conformational Dynamics Revealed by Hydrogen Deuterium Exchange Mass Spectrometry

(2015) Jun Zhang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Higher order structure characterization of protein therapeutics by hydrogen/deuterium exchange mass spectrometry

(2014) Richard Y.-C. Huang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life

(2014) Ranajoy Majumdar et al.   mAbs

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

(2014) Enrico Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications

(2013) Hui Wei et al.   DRUG DISCOVERY TODAY

Peptide–Column Interactions and Their Influence on Back Exchange Rates in Hydrogen/Deuterium Exchange-MS

(2013) Joey G. Sheff et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Protein hydrogen exchange at residue resolution by proteolytic fragmentation mass spectrometry analysis

(2013) Z.-Y. Kan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

(2013) Enrico Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stepwise protein folding at near amino acid resolution by hydrogen exchange and mass spectrometry

(2013) W. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ab initiostructure prediction of the antibody hypervariable H3 loop

(2013) Kai Zhu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Hydrogen/Deuterium Exchange and Electron-Transfer Dissociation Mass Spectrometry Determine the Interface and Dynamics of Apolipoprotein E Oligomerization

(2011) Richard Y-C. Huang et al.   BIOCHEMISTRY

Automated Hydrogen/Deuterium Exchange Electron Transfer Dissociation High Resolution Mass Spectrometry Measured at Single-Amide Resolution

(2011) Rachelle R. Landgraf et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Many Overlapping Peptides for Protein Hydrogen Exchange Experiments by the Fragment Separation-Mass Spectrometry Method

(2011) Leland Mayne et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Decoy Strategies: The Structure of TL1A:DcR3 Complex

(2011) Chenyang Zhan et al.   STRUCTURE

Protein Hydrogen Exchange Measured at Single-Residue Resolution by Electron Transfer Dissociation Mass Spectrometry

(2009) Kasper D. Rand et al.   ANALYTICAL CHEMISTRY

High-Speed and High-Resolution UPLC Separation at Zero Degrees Celsius

(2008) Thomas E. Wales et al.   ANALYTICAL CHEMISTRY

The generalized Born/volume integral implicit solvent model: Estimation of the free energy of hydration using London dispersion instead of atomic surface area

(2008) Paul Labute   JOURNAL OF COMPUTATIONAL CHEMISTRY

A yeast display immunoprecipitation method for efficient isolation and characterization of antigens

(2008) Yong Ku Cho et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Electron Transfer Dissociation Facilitates the Measurement of Deuterium Incorporation into Selectively Labeled Peptides with Single Residue Resolution

(2008) Martin Zehl et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY