The Intersection of Aging Biology and the Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop

Mechanisms of Chronic Muscle Wasting and Dysfunction after an Intensive Care Unit Stay. A Pilot Study

(2016) Claudia dos Santos et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Trans-Omics: How To Reconstruct Biochemical Networks Across Multiple ‘Omic’ Layers

(2016) Katsuyuki Yugi et al.   TRENDS IN BIOTECHNOLOGY

Interventions to Slow Aging in Humans: Are We Ready?

(2015) Valter D. Longo et al.   AGING CELL

Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1

(2015) Meredith L. Sosulski et al.   AGING CELL

Blue Journal Conference. Aging and Susceptibility to Lung Disease

(2015) Victor J. Thannickal et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Muscle Dysfunction in Patients with Lung Diseases. A Growing Epidemic

(2015) Esther Barreiro et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

Epigenetics in idiopathic pulmonary fibrosis

(2015) Argyrios Tzouvelekis et al.   Biochemistry and Cell Biology

Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective

(2015) E Andres Houseman et al.   BMC BIOINFORMATICS

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Evolution of Mitochondria as Signaling Organelles

(2015) Navdeep S. Chandel   Cell Metabolism

Intrinsic and extrinsic mechanisms regulating satellite cell function

(2015) N. A. Dumont et al.   DEVELOPMENT

Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease

(2015) Tanveer Ahmad et al.   FASEB JOURNAL

Drivers of age-related inflammation and strategies for healthspan extension

(2015) Emily L. Goldberg et al.   IMMUNOLOGICAL REVIEWS

Measuring In Vivo Mitophagy

(2015) Nuo Sun et al.   MOLECULAR CELL

Repression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction

(2015) Johnathan Labbadia et al.   MOLECULAR CELL

Time- and compartment-resolved proteome profiling of the extracellular niche in lung injury and repair

(2015) H. B. Schiller et al.   Molecular Systems Biology

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis

(2015) Sandra Pankow et al.   NATURE

The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation

(2015) Qiao Zhang et al.   NATURE IMMUNOLOGY

The Asthma–COPD Overlap Syndrome

(2015) Dirkje S. Postma et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease

(2015) Peter Lange et al.   NEW ENGLAND JOURNAL OF MEDICINE

A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

(2015) M. Mohrin et al.   SCIENCE

‘LungGENS’: a web-based tool for mapping single-cell gene expression in the developing lung: Figure 1

(2015) Yina Du et al.   THORAX

Accelerated ageing of the lung in COPD: new concepts

(2015) Nicolas Mercado et al.   THORAX

Revealing the Pathogenic and Aging-related Mechanisms of the Enigmatic Idiopathic Pulmonary Fibrosis. An Integral Model

(2014) Moisés Selman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An Official American Thoracic Society/European Respiratory Society Statement: Update on Limb Muscle Dysfunction in Chronic Obstructive Pulmonary Disease

(2014) François Maltais et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Epigenetic mechanisms in COPD: implications for pathogenesis and drug discovery

(2014) Andrea C Schamberger et al.   Expert Opinion on Drug Discovery

Telomerase mutations in smokers with severe emphysema

(2014) Susan E. Stanley et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

(2014) Kenji Mizumura et al.   JOURNAL OF CLINICAL INVESTIGATION

PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis

(2014) Marta Bueno et al.   JOURNAL OF CLINICAL INVESTIGATION

Genome-wide association analysis identifies six new loci associated with forced vital capacity

(2014) Daan W Loth et al.   NATURE GENETICS

Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance

(2014) L. Hecker et al.   Science Translational Medicine

A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease

(2014) Marc Brehme et al.   Cell Reports

Quantitative reconstruction of leukocyte subsets using DNA methylation

(2014) William P Accomando et al.   GENOME BIOLOGY

Heterochronic parabiosis: historical perspective and methodological considerations for studies of aging and longevity

(2013) Michael J. Conboy et al.   AGING CELL

Population-based Incidence Estimates of Influenza-associated Respiratory Failure Hospitalizations, 2003 to 2009

(2013) Justin R. Ortiz et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung

(2013) Alexander V. Misharin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A Multidimensional Index and Staging System for Idiopathic Pulmonary Fibrosis

(2013) Brett Ley et al.   ANNALS OF INTERNAL MEDICINE

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Regulation of Organismal Proteostasis by Transcellular Chaperone Signaling

(2013) Patricija van Oosten-Hawle et al.   CELL

Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

(2013) Francesco S. Loffredo et al.   CELL

COPD Surveillance—United States, 1999-2011

(2013) Earl S. Ford et al.   CHEST

Acute Skeletal Muscle Wasting in Critical Illness

(2013) Zudin A. Puthucheary et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Rapamycin extends murine lifespan but has limited effects on aging

(2013) Frauke Neff et al.   JOURNAL OF CLINICAL INVESTIGATION

Causes, consequences, and reversal of immune system aging

(2013) Encarnacion Montecino-Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

Disorders of Protein Misfolding: Alpha-1-Antitrypsin Deficiency as Prototype

(2013) Gary A. Silverman et al.   JOURNAL OF PEDIATRICS

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

Diversity in the origins of proteostasis networks — a driver for protein function in evolution

(2013) Evan T. Powers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Intersection Between Aging and Cardiovascular Disease

(2012) Brian J. North et al.   CIRCULATION RESEARCH

Gene promoter methylation is associated with lung function in the elderly: The normative aging study

(2012) Johanna Lepeule et al.   Epigenetics

Multi-ethnic reference values for spirometry for the 3–95-yr age range: the global lung function 2012 equations

(2012) Philip H. Quanjer et al.   EUROPEAN RESPIRATORY JOURNAL

Age‐related expression, enzymatic solubility and modification with advanced glycation end‐products of fibrillar collagens in mouse lung

(2012) Paulina Rolewska et al.   EXPERIMENTAL GERONTOLOGY

Mitochondrial Reactive Oxygen Species Regulate Transforming Growth Factor-β Signaling

(2012) Manu Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomere Length Is a Determinant of Emphysema Susceptibility

(2011) Jonathan K. Alder et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

(2011) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells

(2011) Brad Dykstra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Idiopathic pulmonary fibrosis

(2011) Talmadge E King et al.   LANCET

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Genome sequencing reveals insights into physiology and longevity of the naked mole rat

(2011) Eun Bae Kim et al.   NATURE

Firefly luciferase mutants as sensors of proteome stress

(2011) Rajat Gupta et al.   NATURE METHODS

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age

(2011) W. W. Pang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noninfectious Pneumonitis after Everolimus Therapy for Advanced Renal Cell Carcinoma

(2010) Dorothy A. White et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Modeling general proteostasis: proteome balance in health and disease

(2010) Daniela M Roth et al.   CURRENT OPINION IN CELL BIOLOGY

Comprehensive methylome map of lineage commitment from haematopoietic progenitors

(2010) Hong Ji et al.   NATURE

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Accurate whole human genome sequencing using reversible terminator chemistry

(2008) David R. Bentley et al.   NATURE

Design and analysis of ChIP-seq experiments for DNA-binding proteins

(2008) Peter V Kharchenko et al.   NATURE BIOTECHNOLOGY

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

(2008) Zhi-Hua Chen et al.   PLoS One

The Transcriptional Landscape of the Yeast Genome Defined by RNA Sequencing

(2008) U. Nagalakshmi et al.   SCIENCE

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE