Effect of major gastrointestinal tract surgery on the absorption and efficacy of direct acting oral anticoagulants (DOACs)

Antithrombotic Therapy for VTE Disease

(2016) Clive Kearon et al.   CHEST

Extracranial Systemic Embolic Events in Patients With Nonvalvular Atrial FibrillationCLINICAL PERSPECTIVE

(2015) Wobo Bekwelem et al.   CIRCULATION

Pharmacokinetics and Pharmacodynamics of Edoxaban, a Non-Vitamin K Antagonist Oral Anticoagulant that Inhibits Clotting Factor Xa

(2015) Dolly A. Parasrampuria et al.   CLINICAL PHARMACOKINETICS

Relative Bioavailability of Apixaban Solution or Crushed Tablet Formulations Administered by Mouth or Nasogastric Tube in Healthy Subjects

(2015) Yan Song et al.   CLINICAL THERAPEUTICS

Updated European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist anticoagulants in patients with non-valvular atrial fibrillation

(2015) Hein Heidbuchel et al.   EUROPACE

Evaluation of regional gastrointestinal absorption of edoxaban using the enterion capsule

(2015) Dolly A. Parasrampuria et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Proximal Roux-en-Y Gastric Bypass Alters Drug Absorption Pattern But Not Systemic Exposure of CYP3A4 and P-glycoprotein Substrates

(2015) Lingtak-Neander Chan et al.   PHARMACOTHERAPY

Gastrointestinal bleeding in patients receiving oral anticoagulation: Current treatment and pharmacological perspectives

(2015) Alessandro Di Minno et al.   THROMBOSIS RESEARCH

Rivaroxaban as anticoagulant therapy in short bowel syndrome. Report of three cases

(2015) Line Dahlstrøm Christensen et al.   THROMBOSIS RESEARCH

Insufficient anticoagulation with dabigatran in a patient with short bowel syndrome

(2014) Ludwig Schlemm et al.   THROMBOSIS AND HAEMOSTASIS

Drug-Drug Interaction Studies of Cardiovascular Drugs Involving P-Glycoprotein, an Efflux Transporter, on the Pharmacokinetics of Edoxaban, an Oral Factor Xa Inhibitor

(2013) Jeanne Mendell et al.   American Journal of Cardiovascular Drugs

Treatment of Acute Venous Thromboembolism With Dabigatran or Warfarin and Pooled Analysis

(2013) Sam Schulman et al.   CIRCULATION

Clinical Pharmacokinetic and Pharmacodynamic Profile of Rivaroxaban

(2013) Wolfgang Mueck et al.   CLINICAL PHARMACOKINETICS

Novel oral anticoagulants in gastroenterology practice

(2013) Jay Desai et al.   GASTROINTESTINAL ENDOSCOPY

Pharmacokinetics of rivaroxaban after bariatric surgery: a case report

(2013) Adrian Mahlmann et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Oral Apixaban for the Treatment of Acute Venous Thromboembolism

(2013) Giancarlo Agnelli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Consequences of Gastrointestinal Surgery on Drug Absorption

(2013) Rachel Titus et al.   NUTRITION IN CLINICAL PRACTICE

Incidence of Venous Thromboembolism After Bariatric Surgery: A Population-Based Cohort Study

(2013) David A. Froehling et al.   OBESITY SURGERY

Apixaban, an oral, direct factor Xa inhibitor: single dose safety, pharmacokinetics, pharmacodynamics and food effect in healthy subjects

(2012) Charles Frost et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Analysis of Upper Gastrointestinal Adverse Events Among Patients Given Dabigatran in the RE-LY Trial

(2012) Peter Bytzer et al.   Clinical Gastroenterology and Hepatology

Clinical presentation of venous thromboembolism in inflammatory bowel disease

(2012) Pavol Papay et al.   Journal of Crohns & Colitis

Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF

(2012) Graeme J Hankey et al.   LANCET NEUROLOGY

Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial

(2012) J Donald Easton et al.   LANCET NEUROLOGY

Accurate determination of rivaroxaban levels requires different calibrator sets but not addition of antithrombin

(2012) Gabriele Rohde et al.   THROMBOSIS AND HAEMOSTASIS

Population pharmacokinetic analysis of the oral thrombin inhibitor dabigatran etexilate in patients with non-valvular atrial fibrillation from the RE-LY trial

(2011) K.-H. LIESENFELD et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Dabigatran: An Oral Novel Potent Reversible Nonpeptide Inhibitor of Thrombin

(2010) Wolfgang G. Eisert et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effects of Food on the Pharmacokinetics of Edoxaban, an Oral Direct Factor Xa Inhibitor, in Healthy Volunteers

(2010) Jeanne Mendell et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial

(2010) Hans-Christoph Diener et al.   LANCET NEUROLOGY

Oral Rivaroxaban for Symptomatic Venous Thromboembolism

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation

(2010) Stuart Connolly et al.   THROMBOSIS AND HAEMOSTASIS

Dabigatran versus Warfarin in Patients with Atrial Fibrillation

(2009) Stuart J. Connolly et al.   NEW ENGLAND JOURNAL OF MEDICINE

A systematic review of drug absorption following bariatric surgery and its theoretical implications

(2009) R. Padwal et al.   Obesity Reviews

Scintigraphic Evaluation of Gastric Emptying in Obese Patients Submitted to Sleeve Gastrectomy Compared to Normal Subjects

(2009) Italo Braghetto et al.   OBESITY SURGERY

Pharmacokinetics and Pharmacodynamics of Dabigatran Etexilate, an Oral Direct Thrombin Inhibitor, Are Not Affected by Moderate Hepatic Impairment

(2008) Joachim Stangier et al.   JOURNAL OF CLINICAL PHARMACOLOGY