Physiologic and pathophysiologic roles of interaction between C-type lectin-like receptor 2 and podoplanin: partners fromin uteroto adulthood

C-type lectin-like receptor 2 promotes hematogenous tumor metastasis and prothrombotic state in tumor-bearing mice

(2017) T. Shirai et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Podoplanin-positive periarteriolar stromal cells promote megakaryocyte growth and proplatelet formation in mice by CLEC-2

(2016) S. Tamura et al.   BLOOD

Novel functions of platelets in the liver

(2016) Tomohiro Kurokawa et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development

(2015) K. L. Lowe et al.   BLOOD

Single platelets seal neutrophil-induced vascular breaches via GPVI during immune-complex-mediated inflammation in mice

(2015) A. Gros et al.   BLOOD

Horizontal RNA transfer mediates platelet-induced hepatocyte proliferation

(2015) M. Kirschbaum et al.   BLOOD

Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets

(2015) Jessica R. Hitchcock et al.   JOURNAL OF CLINICAL INVESTIGATION

CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow

(2015) Ayako Nakamura-Ishizu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A focus on the role of platelets in liver regeneration: Do platelet-endothelial cell interactions initiate the regenerative process?

(2015) Jeremy Meyer et al.   JOURNAL OF HEPATOLOGY

Vascular Smooth Muscle Cells Stimulate Platelets and Facilitate Thrombus Formation through Platelet CLEC-2: Implications in Atherothrombosis

(2015) Osamu Inoue et al.   PLoS One

CLEC-2 is required for development and maintenance of lymph nodes

(2014) C. Benezech et al.   BLOOD

Syk and Src Family Kinases Regulate C-type Lectin Receptor 2 (CLEC-2)-mediated Clustering of Podoplanin and Platelet Adhesion to Lymphatic Endothelial Cells

(2014) Alice Y. Pollitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dendritic cells control fibroblastic reticular network tension and lymph node expansion

(2014) Sophie E. Acton et al.   NATURE

The CLEC-2–podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture

(2014) Jillian L Astarita et al.   NATURE IMMUNOLOGY

Clinicopathological Correlations of Podoplanin (gp38) Expression in Rheumatoid Synovium and Its Potential Contribution to Fibroblast Platelet Crosstalk

(2014) Manuel J. Del Rey et al.   PLoS One

Distribution of Podoplanin-Expressing Cells in the Mouse Nervous Systems

(2013) Miwa Tomooka et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Combined In Vivo Depletion of Glycoprotein VI and C-Type Lectin-Like Receptor 2 Severely Compromises Hemostasis and Abrogates Arterial Thrombosis in Mice

(2013) Markus Bender et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life

(2013) Paul R. Hess et al.   JOURNAL OF CLINICAL INVESTIGATION

Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

(2013) Brett H. Herzog et al.   NATURE

Platelets Promote Tumor Growth and Metastasis via Direct Interaction between Aggrus/Podoplanin and CLEC-2

(2013) Satoshi Takagi et al.   PLoS One

The physiological and pathophysiological roles of platelet CLEC-2

(2013) Stacey A. Langan et al.   THROMBOSIS AND HAEMOSTASIS

Preventing Germinal Matrix Layer Rupture and Intraventricular Hemorrhage

(2013) Ronald W. Coen   Frontiers in Pediatrics

Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2

(2012) Sophie E. Acton et al.   IMMUNITY

Platelet Activation Receptor CLEC-2 Regulates Blood/Lymphatic Vessel Separation by Inhibiting Proliferation, Migration, and Tube Formation of Lymphatic Endothelial Cells

(2012) Makoto Osada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel platelet activation receptor CLEC-2: from discovery to prospects

(2011) K. SUZUKI-INOUE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The novel platelet activation receptor CLEC-2

(2011) Katsue Suzuki-Inoue et al.   PLATELETS

Bleeding response induced by anti-thrombotic doses of a phosphoinositide 3-kinase (PI3K)-β inhibitor in mice

(2011) J. Eileen Bird et al.   THROMBOSIS RESEARCH

Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation

(2010) P. Uhrin et al.   BLOOD

Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling

(2010) C. C. Bertozzi et al.   BLOOD

Lymphangiogenesis: Molecular Mechanisms and Future Promise

(2010) Tuomas Tammela et al.   CELL

Stress-induced non-vesicular release of prothymosin-α initiated by an interaction with S100A13 and its blockade by caspase-3 cleavage

(2010) H Matsunaga et al.   CELL DEATH AND DIFFERENTIATION

Essentialin VivoRoles of the C-type Lectin Receptor CLEC-2

(2010) Katsue Suzuki-Inoue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel mechanism of cytokine release in phagocytes induced by aggretin, a snake venom C-type lectin protein, through CLEC-2 ligation

(2010) C.-H. CHANG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

CLEC-2 is not required for platelet aggregation at arteriolar shear

(2010) C. E. HUGHES et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A mouse knockout library for secreted and transmembrane proteins

(2010) Tracy Tang et al.   NATURE BIOTECHNOLOGY

NMR characterization of copper and lipid interactions of the C2B domain of synaptotagmin I—relevance to the non-classical secretion of the human acidic fibroblast growth factor (hFGF-1)

(2009) Karuppanan Muthusamy Kathir et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis

(2009) F. May et al.   BLOOD

CLEC-2 Is a Phagocytic Activation Receptor Expressed on Murine Peripheral Blood Neutrophils

(2009) A. M. Kerrigan et al.   JOURNAL OF IMMUNOLOGY

Novel interactions in platelet biology: CLEC-2/podoplanin and laminin/GPVI

(2009) Y. OZAKI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Intraventricular Hemorrhage in Premature Infants: Mechanism of Disease

(2009) Praveen Ballabh   PEDIATRIC RESEARCH

Renal cells activate the platelet receptor CLEC-2 through podoplanin

(2008) Charita M. Christou et al.   BIOCHEMICAL JOURNAL

Inflammation induces hemorrhage in thrombocytopenia

(2008) T. Goerge et al.   BLOOD

Phospholipase C 2 is necessary for separation of blood and lymphatic vasculature in mice

(2008) H. Ichise et al.   DEVELOPMENT

Platelet aggregation in the formation of tumor metastasis

(2008) Takashi TSURUO et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES