Altering intracellular pH reveals the kinetic basis of intraburst gating in the CFTR Cl−channel

Positioning of extracellular loop 1 affects pore gating of the cystic fibrosis transmembrane conductance regulator

(2016) Daniel T. Infield et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Timing of CFTR Pore Opening and Structure of Its Transition State

(2015) Ben Sorum et al.   CELL

Impact of the F508del mutation on ovine CFTR, a Cl−channel with enhanced conductance and ATP-dependent gating

(2015) Zhiwei Cai et al.   JOURNAL OF PHYSIOLOGY-LONDON

Localizing a gate in CFTR

(2015) Xiaolong Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three charged amino acids in extracellular loop 1 are involved in maintaining the outer pore architecture of CFTR

(2014) Guiying Cui et al.   JOURNAL OF GENERAL PHYSIOLOGY

Conformational changes in the catalytically inactive nucleotide-binding site of CFTR

(2013) László Csanády et al.   JOURNAL OF GENERAL PHYSIOLOGY

The CFTR Ion Channel: Gating, Regulation, and Anion Permeation

(2013) T.-C. Hwang et al.   Cold Spring Harbor Perspectives in Medicine

Identification of a novel post-hydrolytic state in CFTR gating

(2012) Kang-Yang Jih et al.   JOURNAL OF GENERAL PHYSIOLOGY

The most common cystic fibrosis-associated mutation destabilizes the dimeric state of the nucleotide-binding domains of CFTR

(2011) Kang-Yang Jih et al.   JOURNAL OF PHYSIOLOGY-LONDON

Human-mouse cystic fibrosis transmembrane conductance regulator (CFTR) chimeras identify regions that partially rescue CFTR- F508 processing and alter its gating defect

(2011) Q. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channel

(2010) Ming-Feng Tsai et al.   JOURNAL OF GENERAL PHYSIOLOGY

Direct Sensing of Intracellular pH by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Cl−Channel

(2009) Jeng-Haur Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

State-dependent modulation of CFTR gating by pyrophosphate

(2009) Ming-Feng Tsai et al.   JOURNAL OF GENERAL PHYSIOLOGY

Strict coupling between CFTR's catalytic cycle and gating of its Cl- ion pore revealed by distributions of open channel burst durations

(2009) L. Csanady et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic model of human cystic fibrosis transmembrane conductance regulator: Membrane-spanning domains and coupling interfaces

(2008) J.-P. Mornon et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

(2008) A. W. R. Serohijos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA