Regulatory Effects and Mechanism of Adenovirus-Mediated PTEN Gene on Hepatic Stellate Cells

Akt—mTOR Pathway Inhibits Apoptosis and Fibrosis in Doxorubicin-Induced Cardiotoxicity following Embryonic Stem Cell Transplantation

(2015) Dinender K. Singla   CELL TRANSPLANTATION

Hepatocyte-targeting gene delivery using a lipoplex composed of galactose-modified aromatic lipid synthesized with click chemistry

(2014) Mizuha Sakashita et al.   BIOORGANIC & MEDICINAL CHEMISTRY

MicroRNA-mediated multi-tissue detargeting of oncolytic measles virus

(2014) M A Baertsch et al.   CANCER GENE THERAPY

Antifibrotic effects of luteolin on hepatic stellate cells and liver fibrosis by targeting AKT/mTOR/p70S6K and TGFβ/Smad signalling pathways

(2014) Jie Li et al.   LIVER INTERNATIONAL

Schistosoma japonicum Soluble Egg Antigens Facilitate Hepatic Stellate Cell Apoptosis by Downregulating Akt Expression and Upregulating p53 and DR5 Expression

(2014) Jianxin Wang et al.   PLoS Neglected Tropical Diseases

Knockdown ofAKT3(PKBγ) andPI3KCASuppresses Cell Viability and Proliferation and Induces the Apoptosis of Glioblastoma Multiforme T98G Cells

(2014) Monika Paul-Samojedny et al.   Biomed Research International

Tumour selective targeting of cell cycle kinases for cancer treatment

(2013) Marieke Aarts et al.   CURRENT OPINION IN PHARMACOLOGY

Mitochondrial genome depletion in human liver cells abolishes bile acid-induced apoptosis: Role of the Akt/mTOR survival pathway and Bcl-2 family proteins

(2013) Jose J.G. Marin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Apoptotic effect of propyl gallate in activated rat hepatic stellate cells

(2012) Xian-Hua Che et al.   ARCHIVES OF PHARMACAL RESEARCH

Targeting Focal Adhesion Kinase in Fibrotic Diseases

(2012) David Lagares et al.   BIODRUGS

Disorder-function relationships for the cell cycle regulatory proteins p21 and p27

(2012) Diana M. Mitrea et al.   BIOLOGICAL CHEMISTRY

PTEN/MAPK pathways play a key role in platelet-activating factor-induced experimental pulmonary tumor metastasis

(2012) Han-A Kim et al.   FEBS LETTERS

PTEN at a glance

(2012) Y. Shi et al.   JOURNAL OF CELL SCIENCE

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

(2012) T. Kisseleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Migration of Fibrocytes in Fibrogenic Liver Injury

(2011) David Scholten et al.   AMERICAN JOURNAL OF PATHOLOGY

Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

Down-regulation of focal adhesion kinase by short hairpin RNA increased apoptosis of rat hepatic stellate cells

(2011) JUNYAN AN et al.   APMIS

PI(3)King Apart PTEN's Role in Cancer

(2010) S. Zhang et al.   CLINICAL CANCER RESEARCH

Septum transversum-derived mesothelium gives rise to hepatic stellate cells and perivascular mesenchymal cells in developing mouse liver

(2010) Kinji Asahina et al.   HEPATOLOGY

New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis

(2010) Yan Wang et al.   JOURNAL OF HEPATOLOGY

Pathogenese der Leberfibrose: Regulation von hepatischen Sternzellen durch Chemokine

(2010) H. Wasmuth et al.   ZEITSCHRIFT FUR GASTROENTEROLOGIE

PTEN expression is down-regulated in liver tissues of rats with hepatic fibrosis induced by biliary stenosis

(2009) LI SEN HAO et al.   APMIS

The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation

(2009) Motoki Takashima et al.   JOURNAL OF GASTROENTEROLOGY

Raf kinase inhibitor protein inhibits cell proliferation but promotes cell migration in rat hepatic stellate cells

(2009) Junji Ma et al.   LIVER INTERNATIONAL

UVB-induced ERK/AKT-dependent PTEN suppression promotes survival of epidermal keratinocytes

(2009) M Ming et al.   ONCOGENE

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

(2008) A. Dubrovska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTEN Down-Regulation by Unsaturated Fatty Acids Triggers Hepatic Steatosis via an NF-κBp65/mTOR-Dependent Mechanism

(2007) Manlio Vinciguerra et al.   GASTROENTEROLOGY