Antifibrotic effects of luteolin on hepatic stellate cells and liver fibrosis by targeting AKT/mTOR/p70S6K and TGFβ/Smad signalling pathways

Mechanisms of hepatic fibrogenesis

(2011) Ursula E. Lee et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib

(2011) Yuqing Liu et al.   JOURNAL OF HEPATOLOGY

Anti-carcinogenic Effects of the Flavonoid Luteolin

(2011) Günter Seelinger et al.   MOLECULES

New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis

(2010) Yan Wang et al.   JOURNAL OF HEPATOLOGY

Hepatic fibrogenesis in response to chronic liver injury: novel insights on the role of cell-to-cell interaction and transition

(2010) Gianluca Svegliati-Baroni et al.   LIVER INTERNATIONAL

Hepatocyte nuclear factor 4  attenuates hepatic fibrosis in rats

(2009) H.-Y. Yue et al.   GUT

Inhibition of extracellular signal-regulated kinase 1 by adenovirus mediated small interfering RNA attenuates hepatic fibrosis in rats

(2009) Wei Zhong et al.   HEPATOLOGY

Targeting liver fibrosis: Strategies for development and validation of antifibrotic therapies

(2009) Yury Popov et al.   HEPATOLOGY

Therapeutic targeting of the PDGF and TGF-β-signaling pathways in hepatic stellate cells by PTK787/ZK22258

(2009) Yuqing Liu et al.   LABORATORY INVESTIGATION

Distribution and Biological Activities of the Flavonoid Luteolin

(2009) Miguel Lopez-Lazaro   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Luteolin inhibits invasion of prostate cancer PC3 cells through E-cadherin

(2009) Q. Zhou et al.   MOLECULAR CANCER THERAPEUTICS

Liver fibrosis in mice induced by carbon tetrachloride and its reversion by luteolin

(2009) Robert Domitrović et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Dose- and Time-Dependent Effects of Luteolin on Liver Metallothioneins and Metals in Carbon Tetrachloride-Induced Hepatotoxicity in Mice

(2008) Robert Domitrović et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Anti-Oxidant, Anti-Inflammatory and Anti-Allergic Activities of Luteolin

(2008) Günter Seelinger et al.   PLANTA MEDICA

Phosphatidylinositol 3-kinase/Akt pathway regulates hepatic stellate cell apoptosis

(2008) Yan Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY