Dietary Restriction Ameliorates Age-Related Increase in DNA Damage, Senescence and Inflammation in Mouse Adipose Tissuey

Cellular senescence drives age-dependent hepatic steatosis

(2017) Mikolaj Ogrodnik et al.   Nature Communications

Mitochondria are required for pro‐ageing features of the senescent phenotype

(2016) Clara Correia‐Melo et al.   EMBO JOURNAL

Major role of adipocyte prostaglandin E2in lipolysis-induced macrophage recruitment

(2016) Xiaoqian Hu et al.   JOURNAL OF LIPID RESEARCH

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

Adult-onset, short-term dietary restriction reduces cell senescence in mice

(2016) Chunfang Wang et al.   Aging-US

Promoting Health and Longevity through Diet: From Model Organisms to Humans

(2015) Luigi Fontana et al.   CELL

Adipocyte size as a determinant of metabolic disease and adipose tissue dysfunction

(2015) Sofia Laforest et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Dietary restriction mitigates age-related accumulation of DNA damage, but not all changes in mouse corneal epithelium

(2015) Dean Hallam et al.   EXPERIMENTAL GERONTOLOGY

The Role of Telomerase Protein TERT in Alzheimer's Disease and in Tau-Related Pathology In Vitro

(2015) A. Spilsbury et al.   JOURNAL OF NEUROSCIENCE

Six-month Calorie Restriction in Overweight Individuals Elicits Transcriptomic Response in Subcutaneous Adipose Tissue That is Distinct From Effects of Energy Deficit

(2015) Yan Y. Lam et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Differential Development of Inflammation and Insulin Resistance in Different Adipose Tissue Depots Along Aging in Wistar Rats: Effects of Caloric Restriction

(2015) Johanna X. Sierra Rojas et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Dysregulated LIF-STAT3 pathway is responsible for impaired embryo implantation in a Streptozotocin-induced diabetic mouse model

(2015) T.-S. Wang et al.   Biology Open

Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic Inflammation

(2015) Sardar Sindhu et al.   PLoS One

The Nucleic Acid Scavenger Polyamidoamine Third-Generation Dendrimer Inhibits Fibroblast Activation and Granulation Tissue Contraction

(2014) Eda K. Holl et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice

(2014) Satomi Miwa et al.   Nature Communications

Changes in Adipose Tissue Macrophages and T Cells During Aging

(2013) Sanjay K. Garg et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Adipocyte telomere length associates negatively with adipocyte size, whereas adipose tissue telomere length associates negatively with the extent of fibrosis in severely obese women

(2013) F el Bouazzaoui et al.   INTERNATIONAL JOURNAL OF OBESITY

Adipose tissue, diet and aging

(2013) Mauro Zamboni et al.   MECHANISMS OF AGEING AND DEVELOPMENT

AMP-activated protein kinase: new regulation, new roles?

(2012) David Carling et al.   BIOCHEMICAL JOURNAL

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sexual Dimorphic Regulation of Body Weight Dynamics and Adipose Tissue Lipolysis

(2012) Verena Benz et al.   PLoS One

Murine 3T3-L1 Adipocyte Cell Differentiation Model: Validated Reference Genes for qPCR Gene Expression Analysis

(2012) Tatjana Arsenijevic et al.   PLoS One

Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence

(2012) Graeme Hewitt et al.   Nature Communications

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

(2011) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Gross energy metabolism in mice under late onset, short term caloric restriction

(2011) Kerry M. Cameron et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Caloric restriction

(2011) John R. Speakman et al.   MOLECULAR ASPECTS OF MEDICINE

Dead adipocytes and metabolic dysfunction: recent progress

(2011) Michael West   Current Opinion in Endocrinology Diabetes and Obesity

Fat tissue, aging, and cellular senescence

(2010) Tamara Tchkonia et al.   AGING CELL

Age-associated adaptations in murine adipose tissues

(2010) Bianca Hemmeryckx et al.   ENDOCRINE JOURNAL

Quantitative assessment of markers for cell senescence

(2010) Conor Lawless et al.   EXPERIMENTAL GERONTOLOGY

Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

(2010) Aliki Kosteli et al.   JOURNAL OF CLINICAL INVESTIGATION

Feedback between p21 and reactive oxygen production is necessary for cell senescence

(2010) João F Passos et al.   Molecular Systems Biology

The cyclin-dependent kinase inhibitor p21 is regulated by RNA-binding protein PCBP4 via mRNA stability

(2010) Ariane Scoumanne et al.   NUCLEIC ACIDS RESEARCH

DNA damage response and cellular senescence in tissues of aging mice

(2009) Chunfang Wang et al.   AGING CELL

A crucial role for adipose tissue p53 in the regulation of insulin resistance

(2009) Tohru Minamino et al.   NATURE MEDICINE

Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice

(2008) I. Murano et al.   JOURNAL OF LIPID RESEARCH

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols