How to train glioma cells to die: molecular challenges in cell death

Bevacizumab in high-grade gliomas: past, present, and future

(2015) Richard C Curry et al.   Expert Review of Anticancer Therapy

A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

(2014) Myrna R Rosenfeld et al.   Autophagy

ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 Therapy

(2014) F. Lin et al.   CLINICAL CANCER RESEARCH

NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas

(2014) H.-Y. Cho et al.   MOLECULAR CANCER THERAPEUTICS

VAMP8 facilitates cellular proliferation and temozolomide resistance in human glioma cells

(2014) Yuanyuan Chen et al.   NEURO-ONCOLOGY

Chloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagy

(2014) Encouse B. Golden et al.   Neurosurgical Focus

Bevacizumab for Newly Diagnosed Glioblastoma

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Pregabalin versus Pramipexole for Restless Legs Syndrome

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma

(2013) J Shen et al.   BRITISH JOURNAL OF CANCER

An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma

(2013) David A Reardon et al.   Expert Review of Vaccines

Suppression of Autophagy Enhanced Growth Inhibition and Apoptosis of Interferon-β in Human Glioma Cells

(2013) Yubin Li et al.   MOLECULAR NEUROBIOLOGY

Thymoquinone Inhibits Autophagy and Induces Cathepsin-Mediated, Caspase-Independent Cell Death in Glioblastoma Cells

(2013) Ira O. Racoma et al.   PLoS One

Evaluation of poly (ADP-ribose) polymerase inhibitor ABT-888 combined with radiotherapy and temozolomide in glioblastoma

(2013) Lara Barazzuol et al.   Radiation Oncology

Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma

(2012) Y.-L. Hu et al.   CANCER RESEARCH

Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis

(2012) L. Ouyang et al.   CELL PROLIFERATION

NovoTTF-100A versus physician’s choice chemotherapy in recurrent glioblastoma: A randomised phase III trial of a novel treatment modality

(2012) Roger Stupp et al.   EUROPEAN JOURNAL OF CANCER

Autophagy and cancer - issues we need to digest

(2012) E. Y. Liu et al.   JOURNAL OF CELL SCIENCE

Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner

(2012) L Wagner et al.   ONCOGENE

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

(2012) N. Gammoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prognostic impact of the expression/phosphorylation of the BH3-only proteins of the BCL-2 family in glioblastoma multiforme

(2012) P F Cartron et al.   Cell Death & Disease

What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator

(2011) Alexander H. Stegh et al.   CELL CYCLE

EGFR and EGFRvIII interact with PUMA to inhibit mitochondrial translocalization of PUMA and PUMA-mediated apoptosis independent of EGFR kinase activity

(2010) Hu Zhu et al.   CANCER LETTERS

Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor

(2010) A. H. Stegh et al.   GENES & DEVELOPMENT

Necroptosis: A novel therapeutic target for glioblastoma

(2010) Yu-Gang Jiang et al.   MEDICAL HYPOTHESES

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells

(2009) Peng-fei Ge et al.   ACTA PHARMACOLOGICA SINICA

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

Lysosomes as “Suicide Bags” in Cell Death: Myth or Reality?

(2009) Boris Turk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

(2009) Michael Weller et al.   Nature Reviews Neurology

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins

(2008) David S. Ziegler et al.   JOURNAL OF CLINICAL INVESTIGATION

Delta-24-RGD in Combination With RAD001 Induces Enhanced Anti-glioma Effect via Autophagic Cell Death

(2008) Marta M Alonso et al.   MOLECULAR THERAPY

Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins

(2008) K E Tagscherer et al.   ONCOGENE

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE

Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma

(2008) A. H. Stegh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA