Role of the innate immune system in the neuropathological consequences induced by adolescent binge drinking

Perinatal inflammation and adult psychopathology: From preclinical models to humans

(2018) Amaicha Mara Depino   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Maternal inflammation induces immune activation of fetal microglia and leads to disrupted microglia immune responses, behavior, and learning performance in adulthood

(2017) Wandert Schaafsma et al.   NEUROBIOLOGY OF DISEASE

Binge drinking during adolescence and young adulthood is associated with deficits in verbal episodic memory

(2017) Carina Carbia et al.   PLoS One

Synaptoimmunology - roles in health and disease

(2017) Robert Nisticò et al.   Molecular Brain

The potential of neuroimaging for identifying predictors of adolescent alcohol use initiation and misuse

(2016) Laura O'Halloran et al.   ADDICTION

Adult rat cortical thickness changes across age and following adolescent intermittent ethanol treatment

(2016) Ryan P. Vetreno et al.   ADDICTION BIOLOGY

Gender differences in the inflammatory cytokine and chemokine profiles induced by binge ethanol drinking in adolescence

(2016) María Pascual et al.   ADDICTION BIOLOGY

Evaluation of TLR4 Inhibitor, T5342126, in Modulation of Ethanol-Drinking Behavior in Alcohol-Dependent Mice

(2016) M. Bajo et al.   ALCOHOL AND ALCOHOLISM

The Ability of Functional Magnetic Resonance Imaging to Predict Heavy Drinking and Alcohol Problems 5 Years Later

(2016) Marc A. Schuckit et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Learning and Memory in Adolescent Moderate, Binge, and Extreme-Binge Drinkers

(2016) Tam T. Nguyen-Louie et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Impact of the Innate Immune Response in the Actions of Ethanol on the Central Nervous System

(2016) Jorge Montesinos et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Men and women differ in inflammatory and neuroendocrine responses to endotoxin but not in the severity of sickness symptoms

(2016) Harald Engler et al.   BRAIN BEHAVIOR AND IMMUNITY

Involvement of TLR4 in the long-term epigenetic changes, rewarding and anxiety effects induced by intermittent ethanol treatment in adolescence

(2016) Jorge Montesinos et al.   BRAIN BEHAVIOR AND IMMUNITY

A role for histone acetylation mechanisms in adolescent alcohol exposure-induced deficits in hippocampal brain-derived neurotrophic factor expression and neurogenesis markers in adulthood

(2016) Amul J. Sakharkar et al.   Brain Structure & Function

Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents

(2016) R. Adron Harris et al.   JOURNAL OF NEUROSCIENCE

Addressing the burden of mental, neurological, and substance use disorders: key messages from Disease Control Priorities , 3rd edition

(2016) Vikram Patel et al.   LANCET

Maternal immune activation leads to selective functional deficits in offspring parvalbumin interneurons

(2016) S Canetta et al.   MOLECULAR PSYCHIATRY

Cognitive, emotion control, and motor performance of adolescents in the NCANDA study: Contributions from alcohol consumption, age, sex, ethnicity, and family history of addiction.

(2016) Edith V. Sullivan et al.   NEUROPSYCHOLOGY

Reward-centricity and attenuated aversions: An adolescent phenotype emerging from studies in laboratory animals

(2016) Tamara L. Doremus-Fitzwater et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Immunoadolescence: Neuroimmune development and adolescent behavior

(2016) Heather C. Brenhouse et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Consequences of adolescent use of alcohol and other drugs: Studies using rodent models

(2016) Linda Patia Spear   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Astrocytes contribute to synapse elimination via type 2 inositol 1,4,5-trisphosphate receptor-dependent release of ATP

(2016) Junhua Yang et al.   eLife

Changes in Neuronal Excitability by Activated Microglia: Differential Na+ Current Upregulation in Pyramid-Shaped and Bipolar Neurons by TNF-α and IL-18

(2016) Lars Klapal et al.   Frontiers in Neurology

Adolescent alcohol exposure decreased sensitivity to nicotine in adult Wistar rats

(2015) Nathalie Boutros et al.   ADDICTION BIOLOGY

Diffusion tensor imaging reveals adolescent binge ethanol-induced brain structural integrity alterations in adult rats that correlate with behavioral dysfunction

(2015) Ryan P. Vetreno et al.   ADDICTION BIOLOGY

Acute immunomodulatory effects of binge alcohol ingestion

(2015) Majid Afshar et al.   ALCOHOL

Ethanol Intake Under Social Circumstances or Alone in Sprague-Dawley Rats: Impact of Age, Sex, Social Activity, and Social Anxiety-Like Behavior

(2015) Elena I. Varlinskaya et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Acetaldehyde, Not Ethanol, Impairs Myelin Formation and Viability in Primary Mouse Oligodendrocytes

(2015) David J. C. Coutts et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Pioglitazone Blocks Ethanol Induction of Microglial Activation and Immune Responses in the Hippocampus, Cerebellum, and Cerebral Cortex in a Mouse Model of Fetal Alcohol Spectrum Disorders

(2015) Paul D. Drew et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Adolescent Intermittent Alcohol Exposure: Persistence of Structural and Functional Hippocampal Abnormalities into Adulthood

(2015) Mary-Louise Risher et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

TLR4 elimination prevents synaptic and myelin alterations and long-term cognitive dysfunctions in adolescent mice with intermittent ethanol treatment

(2015) Jorge Montesinos et al.   BRAIN BEHAVIOR AND IMMUNITY

Potential role of adolescent alcohol exposure-induced amygdaloid histone modifications in anxiety and alcohol intake during adulthood

(2015) Subhash C. Pandey et al.   NEUROBIOLOGY OF DISEASE

Role of interleukin-1 receptor signaling in the behavioral effects of ethanol and benzodiazepines

(2015) Yuri A. Blednov et al.   NEUROPHARMACOLOGY

Neuromodulatory properties of inflammatory cytokines and their impact on neuronal excitability

(2015) Annamaria Vezzani et al.   NEUROPHARMACOLOGY

CRF-Amplified Neuronal TLR4/MCP-1 Signaling Regulates Alcohol Self-Administration

(2015) Harry L June et al.   NEUROPSYCHOPHARMACOLOGY

Adolescent Intermittent ethanol exposure enhances ethanol activation of the nucleus accumbens while blunting the prefrontal cortex responses in adult rat

(2015) W. Liu et al.   NEUROSCIENCE

Adolescent alcohol exposure: Are there separable vulnerable periods within adolescence?

(2015) Linda Patia Spear   PHYSIOLOGY & BEHAVIOR

Adolescent binge-like alcohol alters sensitivity to acute alcohol effects on dopamine release in the nucleus accumbens of adult rats

(2015) Tatiana A. Shnitko et al.   PSYCHOPHARMACOLOGY

Structural connectivity of neural reward networks in youth at risk for substance use disorders

(2015) Lindsay M. Squeglia et al.   PSYCHOPHARMACOLOGY

Mechanisms of neuroimmune gene induction in alcoholism

(2015) Fulton T. Crews et al.   PSYCHOPHARMACOLOGY

Adolescent neuroscience of addiction: A new era

(2015) Jay N. Giedd   Developmental Cognitive Neuroscience

Binge ethanol exposure during adolescence leads to a persistent loss of neurogenesis in the dorsal and ventral hippocampus that is associated with impaired adult cognitive functioning

(2015) Ryan P. Vetreno et al.   Frontiers in Neuroscience

Influence of Adolescent Heavy Session Drinking on the Systemic and Brain Innate Immune System

(2014) Roberta J. Ward et al.   ALCOHOL AND ALCOHOLISM

Event-Related Potential Responses to the Acute and Chronic Effects of Alcohol in Adolescent and Adult Wistar Rats

(2014) Cindy L. Ehlers et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Adolescent Alcohol Exposure Alters GABAAReceptor Subunit Expression in Adult Hippocampus

(2014) Samuel W. Centanni et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Innate immune factors modulate ethanol interaction with GABAergic transmission in mouse central amygdala

(2014) Michal Bajo et al.   BRAIN BEHAVIOR AND IMMUNITY

Persistent Loss of Hippocampal Neurogenesis and Increased Cell Death following Adolescent, but Not Adult, Chronic Ethanol Exposure

(2014) Margaret A. Broadwater et al.   DEVELOPMENTAL NEUROSCIENCE

Inflammation early in life is a vulnerability factor for emotional behavior at adolescence and for lipopolysaccharide-induced spatial memory and neurogenesis alteration at adulthood

(2014) Anne-Laure Dinel et al.   Journal of Neuroinflammation

Developmental stages and sex differences of white matter and behavioral development through adolescence: A longitudinal diffusion tensor imaging (DTI) study

(2014) Daniel J. Simmonds et al.   NEUROIMAGE

Adolescent Alcohol Exposure Reduces Behavioral Flexibility, Promotes Disinhibition and Increases Resistance to Extinction of Ethanol Self-Administration in Adulthood

(2014) Justin T Gass et al.   NEUROPSYCHOPHARMACOLOGY

GABAergic contributions to alcohol responsivity during adolescence: Insights from preclinical and clinical studies

(2014) Marisa M. Silveri   PHARMACOLOGY & THERAPEUTICS

Astrocyte-Derived Proinflammatory Cytokines Induce Hypomyelination in the Periventricular White Matter in the Hypoxic Neonatal Brain

(2014) Yiyu Deng et al.   PLoS One

Larger Mid-Dorsolateral Prefrontal Gray Matter Volume in Young Binge Drinkers Revealed by Voxel-Based Morphometry

(2014) Sonia Doallo et al.   PLoS One

Adolescent, but Not Adult, Binge Ethanol Exposure Leads to Persistent Global Reductions of Choline Acetyltransferase Expressing Neurons in Brain

(2014) Ryan P. Vetreno et al.   PLoS One

Life stress in adolescence predicts early adult reward-related brain function and alcohol dependence

(2014) Melynda D. Casement et al.   Social Cognitive and Affective Neuroscience

Microglia Modulate Wiring of the Embryonic Forebrain

(2014) Paola Squarzoni et al.   Cell Reports

Alcohol use and cerebral white matter compromise in adolescence

(2013) Jonathan Elofson et al.   ADDICTIVE BEHAVIORS

Neuroimmune Activation and Myelin Changes in Adolescent Rats Exposed to High-Dose Alcohol and Associated Cognitive Dysfunction: A Review with Reference to Human Adolescent Drinking

(2013) María Pascual et al.   ALCOHOL AND ALCOHOLISM

Effects of a Persistent Binge Drinking Pattern of Alcohol Consumption in Young People: A Follow-Up Study Using Event-Related Potentials

(2013) Eduardo López-Caneda et al.   ALCOHOL AND ALCOHOLISM

Binge-Pattern Ethanol Exposure During Adolescence, but Not Adulthood, Causes Persistent Changes in GABAAReceptor-Mediated Tonic Inhibition in Dentate Granule Cells

(2013) Rebekah L. Fleming et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Consequences of ethanol exposure on cued and contextual fear conditioning and extinction differ depending on timing of exposure during adolescence or adulthood

(2013) Margaret Broadwater et al.   BEHAVIOURAL BRAIN RESEARCH

Molecular triggers of neuroinflammation in mouse models of demyelinating diseases

(2013) Benoit Barrette et al.   BIOLOGICAL CHEMISTRY

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

(2013) Won-Suk Chung et al.   NATURE

Microglial activation is not equivalent to neuroinflammation in alcohol-induced neurodegeneration: The importance of microglia phenotype

(2013) S. Alex Marshall et al.   NEUROBIOLOGY OF DISEASE

Increased receptor for advanced glycation end product expression in the human alcoholic prefrontal cortex is linked to adolescent drinking

(2013) Ryan P. Vetreno et al.   NEUROBIOLOGY OF DISEASE

Periadolescent ethanol vapor exposure persistently reduces measures of hippocampal neurogenesis that are associated with behavioral outcomes in adulthood

(2013) C.L. Ehlers et al.   NEUROSCIENCE

Increased Cortical Activity in Binge Drinkers during Working Memory Task: A Preliminary Assessment through a Functional Magnetic Resonance Imaging Study

(2013) Salvatore Campanella et al.   PLoS One

Sex differences in the structural connectome of the human brain

(2013) M. Ingalhalikar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of alcohol use initiation on brain structure in typically developing adolescents

(2013) Monica Luciana et al.   AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE

A role for synaptic plasticity in the adolescent development of executive function

(2013) L D Selemon   Translational Psychiatry

The association betweenDRD2/ANKK1and genetically informed measures of alcohol use and problems

(2012) Jacquelyn L. Meyers et al.   ADDICTION BIOLOGY

Longitudinal Changes in White Matter Integrity Among Adolescent Substance Users

(2012) Sunita Bava et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Neurotoxic Effects of Alcohol in Adolescence

(2012) Joanna Jacobus et al.   Annual Review of Clinical Psychology

Induction of Bcl-3 by acute binge alcohol results in Toll-like receptor 4/LPS tolerance

(2012) S. Bala et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Changes in histone acetylation in the prefrontal cortex of ethanol-exposed adolescent rats are associated with ethanol-induced place conditioning

(2012) María Pascual et al.   NEUROPHARMACOLOGY

Alcohol intoxications during adolescence increase motivation for alcohol in adult rats and induce neuroadaptations in the nucleus accumbens

(2012) Stéphanie Alaux-Cantin et al.   NEUROPHARMACOLOGY

Adolescent binge drinking increases expression of the danger signal receptor agonist HMGB1 and toll-like receptors in the adult prefrontal cortex

(2012) R.P. Vetreno et al.   NEUROSCIENCE

Microglia in the developing brain: A potential target with lifetime effects

(2012) G. Jean Harry et al.   NEUROTOXICOLOGY

Developmental Trajectories of Amygdala and Hippocampus from Infancy to Early Adulthood in Healthy Individuals

(2012) Akiko Uematsu et al.   PLoS One

Recent binge drinking predicts smaller cerebellar volumes in adolescents

(2012) Krista M. Lisdahl et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Major histocompatibility complex class I proteins in brain development and plasticity

(2012) Bradford M. Elmer et al.   TRENDS IN NEUROSCIENCES

Alcohol use, heavy episodic drinking and subsequent problems among adolescents in 23 European countries: does the prevention paradox apply?

(2011) Anna-Karin Danielsson et al.   ADDICTION

Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies

(2011) Yuri A. Blednov et al.   ADDICTION BIOLOGY

Adolescent Binge Drinking Linked to Abnormal Spatial Working Memory Brain Activation: Differential Gender Effects

(2011) Lindsay M. Squeglia et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Activation of Nuclear PPARγ Receptors by the Antidiabetic Agent Pioglitazone Suppresses Alcohol Drinking and Relapse to Alcohol Seeking

(2011) Serena Stopponi et al.   BIOLOGICAL PSYCHIATRY

Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes

(2011) Maoyin Pang et al.   BMC IMMUNOLOGY

Minocycline reduces ethanol drinking

(2011) R.G. Agrawal et al.   BRAIN BEHAVIOR AND IMMUNITY

Activation of inflammatory signaling by lipopolysaccharide produces a prolonged increase of voluntary alcohol intake in mice

(2011) Y.A. Blednov et al.   BRAIN BEHAVIOR AND IMMUNITY

Molecular and behavioral aspects of the actions of alcohol on the adult and developing brain

(2011) Silvia Alfonso-Loeches et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Role of TLR4 in ethanol effects on innate and adaptive immune responses in peritoneal macrophages

(2011) María Pascual et al.   IMMUNOLOGY AND CELL BIOLOGY

A Lifespan Approach to Neuroinflammatory and Cognitive Disorders: A Critical Role for Glia

(2011) Staci D. Bilbo et al.   Journal of Neuroimmune Pharmacology

Sex steroids and brain structure in pubertal boys and girls: a mini-review of neuroimaging studies

(2011) J.S. Peper et al.   NEUROSCIENCE

Modeling binge-like ethanol drinking by peri-adolescent and adult P rats

(2011) Richard L. Bell et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Binge-Pattern Alcohol Exposure during Puberty Induces Long-Term Changes in HPA Axis Reactivity

(2011) Magdalena M. Przybycien-Szymanska et al.   PLoS One

Alcohol Dysregulates Corticotropin-Releasing-Hormone (CRH) Promoter Activity by Interfering with the Negative Glucocorticoid Response Element (nGRE)

(2011) Magdalena M. Przybycien-Szymanska et al.   PLoS One

Binge drinking differentially affects adolescent male and female brain morphometry

(2011) Lindsay M. Squeglia et al.   PSYCHOPHARMACOLOGY

Mechanisms involved in the neurotoxic, cognitive, and neurobehavioral effects of alcohol consumption during adolescence

(2010) Consuelo Guerri et al.   ALCOHOL

Reduced anterior prefrontal cortex activation in young binge drinkers during a visual working memory task

(2010) Alberto Crego et al.   DRUG AND ALCOHOL DEPENDENCE

Frontal Cortex and the Discovery of Abstract Action Rules

(2010) David Badre et al.   NEURON

N-methyl-d-aspartate receptor subunit expression in adult and adolescent brain following chronic ethanol exposure

(2010) J.P. Pian et al.   NEUROSCIENCE

Long-lasting reduction in hippocampal neurogenesis by alcohol consumption in adolescent nonhuman primates

(2010) M. A. Taffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemical and Neurotransmitter Changes Implicated in Alcohol-Induced Brain Damage in Chronic or 'Binge Drinking' Alcohol Abuse

(2009) R. J. Ward et al.   ALCOHOL AND ALCOHOLISM

Binge Drinking Affects Attentional and Visual Working Memory Processing in Young University Students

(2009) Alberto Crego et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Altered White Matter Integrity in Adolescent Binge Drinkers

(2009) Tim McQueeny et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The Effect of Moderate to Heavy Alcohol Consumption on Neuropsychological Performance as Measured by the Repeatable Battery for the Assessment of Neuropsychological Status

(2009) Alisa Green et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Neurocognitive correlates of white matter quality in adolescent substance users

(2009) Sunita Bava et al.   BRAIN AND COGNITION

“Binge” drinking experience in adolescent mice shows sex differences and elevated ethanol intake in adulthood

(2009) Moriah N. Strong et al.   HORMONES AND BEHAVIOR

Signalling pathways in alcohol-induced liver inflammation

(2009) Pranoti Mandrekar et al.   JOURNAL OF HEPATOLOGY

Critical Role of TLR4 Response in the Activation of Microglia Induced by Ethanol

(2009) S. Fernandez-Lizarbe et al.   JOURNAL OF IMMUNOLOGY

Cerebral inflammation contributes to encephalopathy and brain edema in acute liver failure: protective effect of minocycline

(2009) Wenlei Jiang et al.   JOURNAL OF NEUROCHEMISTRY

Tumor necrosis factor-α-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors

(2009) David Wheeler et al.   JOURNAL OF NEUROCHEMISTRY

Neuro-inflammation induced in the hippocampus of ‘binge drinking’ rats may be mediated by elevated extracellular glutamate content

(2009) Roberta J. Ward et al.   JOURNAL OF NEUROCHEMISTRY

Anatomical Brain Magnetic Resonance Imaging of Typically Developing Children and Adolescents

(2009) Andrew J. Gerber et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Behavioural measures of frontal lobe function in a population of young social drinkers with binge drinking pattern

(2009) J.C. Scaife et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Sex differences in the self-administration of cannabinoids and other drugs of abuse

(2009) Liana Fattore et al.   PSYCHONEUROENDOCRINOLOGY

Intermittent binge alcohol exposure during the periadolescent period induces spatial working memory deficits in young adult rats

(2008) Gery Schulteis et al.   ALCOHOL

Prefrontal Cortex Volumes in Adolescents With Alcohol Use Disorders: Unique Gender Effects

(2008) Krista Lisdahl Medina et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The Teen Brain: Insights from Neuroimaging

(2008) Jay N. Giedd   JOURNAL OF ADOLESCENT HEALTH

Ethanol mimics ligand-mediated activation and endocytosis of IL-1RITLR4 receptors vialipid raftscaveolae in astroglial cells

(2008) Ana M. Blanco et al.   JOURNAL OF NEUROCHEMISTRY

Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat

(2008) Maria Pascual et al.   JOURNAL OF NEUROCHEMISTRY

Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment

(2008) Liya Qin et al.   Journal of Neuroinflammation

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia

(2008) Christopher J Henry et al.   Journal of Neuroinflammation

The hippocampus and memory: insights from spatial processing

(2008) Chris M. Bird et al.   NATURE REVIEWS NEUROSCIENCE

The social brain in adolescence

(2008) Sarah-Jayne Blakemore   NATURE REVIEWS NEUROSCIENCE

Epigenetic mechanisms in drug addiction

(2008) William Renthal et al.   TRENDS IN MOLECULAR MEDICINE

Sex differences in drug abuse

(2007) Jill B. Becker et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages

(2007) Sara Fernandez-Lizarbe et al.   MOLECULAR IMMUNOLOGY