Regional Overlap of Pathologies in Lewy Body Disorders

Updated TDP-43 in Alzheimer’s disease staging scheme

(2016) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Amyloid-β suppresses AMP-activated protein kinase (AMPK) signaling and contributes to α-synuclein-induced cytotoxicity

(2016) Chih-Li Lin et al.   EXPERIMENTAL NEUROLOGY

Distribution and Load of Amyloid-β Pathology in Parkinson Disease and Dementia with Lewy Bodies

(2016) Dagmar H. Hepp et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Hippocampal Sclerosis but Not Normal Aging or Alzheimer Disease Is Associated With TDP-43 Pathology in the Basal Forebrain of Aged Persons

(2016) Matthew D. Cykowski et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

PART is part of Alzheimer disease

(2015) Charles Duyckaerts et al.   ACTA NEUROPATHOLOGICA

Copy number variation analysis of the 17q21.31 region and its role in neurodegenerative diseases

(2015) Laura Cervera-Carles et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Parkinson’s disease dementia: a neural networks perspective

(2015) James Gratwicke et al.   BRAIN

Lewy body dementias

(2015) Zuzana Walker et al.   LANCET

Inhibition of amyloid-β plaque formation by α-synuclein

(2015) Teresa Bachhuber et al.   NATURE MEDICINE

Cortical Lewy bodies and Aβ burden are associated with prevalence and timing of dementia in Lewy body diseases

(2015) C. Ruffmann et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

Convergence of pathology in dementia with Lewy bodies and Alzheimer’s disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease

(2014) Ashley R. Winslow et al.   BRAIN

Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson’s disease

(2014) Hélène Hall et al.   BRAIN

Interactions between Tau and α-synuclein augment neurotoxicity in a Drosophila model of Parkinson's disease

(2014) Bidisha Roy et al.   HUMAN MOLECULAR GENETICS

Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5 – implications for dementia with Lewy bodies

(2014) Cassia R Overk et al.   Molecular Neurodegeneration

The neurobiological basis of cognitive impairment in Parkinson's disease

(2014) Glenda M. Halliday et al.   MOVEMENT DISORDERS

Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons

(2013) Jing L. Guo et al.   CELL

Prominent psychiatric symptoms in patients with Parkinson’s disease and concomitant argyrophilic grain disease

(2013) O. Grau-Rivera et al.   JOURNAL OF NEUROLOGY

Confluence of α-Synuclein, Tau, and β-Amyloid Pathologies in Dementia With Lewy Bodies

(2013) Martí Colom-Cadena et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies

(2013) David J. Irwin et al.   NATURE REVIEWS NEUROSCIENCE

Neuropathology of dementia in a large cohort of patients with Parkinson's disease

(2013) Judit Horvath et al.   PARKINSONISM & RELATED DISORDERS

A Powerful Yeast Model to Investigate the Synergistic Interaction of α-Synuclein and Tau in Neurodegeneration

(2013) Gianmario Ciaccioli et al.   PLoS One

Neuropathologic substrates of Parkinson disease dementia

(2012) David J. Irwin et al.   ANNALS OF NEUROLOGY

Dementia From Alzheimer Disease and Mixed Pathologies in the Oldest Old

(2012) Bryan D. James   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MAPT H1 haplotype is associated with enhanced α-synuclein deposition in dementia with Lewy bodies

(2012) Martí Colom-Cadena et al.   NEUROBIOLOGY OF AGING

Neuropathology underlying clinical variability in patients with synucleinopathies

(2011) Glenda M. Halliday et al.   ACTA NEUROPATHOLOGICA

A peculiar constellation of tau pathology defines a subset of dementia in the elderly

(2011) Gabor G. Kovacs et al.   ACTA NEUROPATHOLOGICA

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important?

(2011) Y. Compta et al.   BRAIN

Striatal β-amyloid in dementia with Lewy bodies but not Parkinson’s disease

(2011) Glenda M. Halliday et al.   JOURNAL OF NEURAL TRANSMISSION

Induction of Intracellular Tau Aggregation Is Promoted by  -Synuclein Seeds and Provides Novel Insights into the Hyperphosphorylation of Tau

(2011) E. A. Waxman et al.   JOURNAL OF NEUROSCIENCE

Clinical features and APOE genotype of pathologically proven early-onset Alzheimer disease

(2011) M. Balasa et al.   NEUROLOGY

Correlations between cortical and subcortical tau pathology

(2011) J. Attems et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Apolipoprotein E4 Frequencies in a Japanese Population with Alzheimer's Disease and Dementia with Lewy Bodies

(2011) Seiju Kobayashi et al.   PLoS One

Tau Enhances α-Synuclein Aggregation and Toxicity in Cellular Models of Synucleinopathy

(2011) Nahuai Badiola et al.   PLoS One

Effect of topographical distribution of α-synuclein pathology on TDP-43 accumulation in Lewy body disease

(2010) Osamu Yokota et al.   ACTA NEUROPATHOLOGICA

Relationships between age and late progression of Parkinson's disease: a clinico-pathological study

(2010) P. A. Kempster et al.   BRAIN

Synergistic Interactions between A , Tau, and  -Synuclein: Acceleration of Neuropathology and Cognitive Decline

(2010) L. K. Clinton et al.   JOURNAL OF NEUROSCIENCE

Striatal Aβ peptide deposition mirrors dementia and differentiates DLB and PDD from other Parkinsonian syndromes

(2010) M.E. Kalaitzakis et al.   NEUROBIOLOGY OF DISEASE

Correlation of Clinical Features With Argyrophilic Grains at Autopsy

(2009) Marwan N. Sabbagh et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Genome-wide association study reveals genetic risk underlying Parkinson's disease

(2009) Javier Simón-Sánchez et al.   NATURE GENETICS

Tau-positive grains are constant in centenarians’ hippocampus

(2009) Chi-Tuan Pham et al.   NEUROBIOLOGY OF AGING

Neuropathology of non-motor features of Parkinson disease

(2009) Dennis W. Dickson et al.   PARKINSONISM & RELATED DISORDERS

Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease

(2008) Kurt A. Jellinger et al.   ACTA NEUROPATHOLOGICA

Cortical α-synuclein load is associated with amyloid-β plaque burden in a subset of Parkinson’s disease patients

(2008) Tammaryn Lashley et al.   ACTA NEUROPATHOLOGICA

Striatal β-Amyloid Deposition in Parkinson Disease With Dementia

(2008) Michail E. Kalaitzakis et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Early-Onset Familial Lewy Body Dementia With Extensive Tauopathy: A Clinical, Genetic, and Neuropathological Study

(2008) Jordi Clarimón et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

(2008) Igor F. Tsigelny et al.   PLoS One