Interactions between Tau and α-synuclein augment neurotoxicity in a Drosophila model of Parkinson's disease

Paraquat, but Not Maneb, Induces Synucleinopathy and Tauopathy in Striata of Mice through Inhibition of Proteasomal and Autophagic Pathways

(2012) Jonathan Wills et al.   PLoS One

Hyperphosphorylated Tau in an α-synuclein-overexpressing transgenic model of Parkinson’s disease

(2011) Thomas Haggerty et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation

(2011) Surendra S. Ambegaokar et al.   HUMAN MOLECULAR GENETICS

Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila

(2011) Yasmina Talmat-Amar et al.   HUMAN MOLECULAR GENETICS

Drosophila Acyl-CoA Synthetase Long-Chain Family Member 4 Regulates Axonal Transport of Synaptic Vesicles and Is Required for Synaptic Development and Transmission

(2011) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

(2011) Cristian A Lasagna-Reeves et al.   Molecular Neurodegeneration

Glial-Derived Prodegenerative Signaling in the Drosophila Neuromuscular System

(2011) Lani C. Keller et al.   NEURON

Tauopathic Changes in the Striatum of A53T α-Synuclein Mutant Mouse Model of Parkinson's Disease

(2011) Jonathan Wills et al.   PLoS One

TDP-43 Regulates Drosophila Neuromuscular Junctions Growth by Modulating Futsch/MAP1B Levels and Synaptic Microtubules Organization

(2011) Vinay K. Godena et al.   PLoS One

The synaptic pathology of α-synuclein aggregation in dementia with Lewy bodies, Parkinson’s disease and Parkinson’s disease dementia

(2010) Walter J. Schulz-Schaeffer   ACTA NEUROPATHOLOGICA

Genome-Wide Association Study Confirms SNPs inSNCAand theMAPTRegion as Common Risk Factors for Parkinson Disease

(2010) Todd L. Edwards et al.   ANNALS OF HUMAN GENETICS

SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease

(2010) Pablo Garcia-Reitböck et al.   BRAIN

Membrane Interactions of Oligomeric Alpha-Synuclein: Potential Role in Parkinsons Disease

(2010) Bart D. van Rooijen et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

α-Synuclein sequesters arachidonic acid to modulate SNARE-mediated exocytosis

(2010) Frédéric Darios et al.   EMBO REPORTS

Interaction Between Eye Pigment Genes and Tau-Induced Neurodegeneration in Drosophila melanogaster

(2010) Surendra S. Ambegaokar et al.   GENETICS

LRRK2 Kinase Regulates Synaptic Morphology through Distinct Substrates at the Presynaptic and Postsynaptic Compartments of the Drosophila Neuromuscular Junction

(2010) S. Lee et al.   JOURNAL OF NEUROSCIENCE

A Pathologic Cascade Leading to Synaptic Dysfunction in  -Synuclein-Induced Neurodegeneration

(2010) D. A. Scott et al.   JOURNAL OF NEUROSCIENCE

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

Synapsin regulates vesicle organization and activity-dependent recycling at Drosophila motor boutons

(2010) Y. Akbergenova et al.   NEUROSCIENCE

Membrane Permeabilization by Oligomeric α-Synuclein: In Search of the Mechanism

(2010) Bart D. van Rooijen et al.   PLoS One

 -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

(2010) J. Burre et al.   SCIENCE

The proline-rich domain of tau plays a role in interactions with actin

(2009) Hai He et al.   BMC CELL BIOLOGY

Dual roles of Drosophila p53 in cell death and cell differentiation

(2009) Y Fan et al.   CELL DEATH AND DIFFERENTIATION

α-Synuclein contributes to GSK-3β-catalyzed Tau phosphorylation in Parkinson’s disease models

(2009) Tetyana Duka et al.   FASEB JOURNAL

Curvature Dynamics of α-Synuclein Familial Parkinson Disease Mutants

(2009) Jason D. Perlmutter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PP2A and GSK-3  Act Antagonistically to Regulate Active Zone Development

(2009) N. M. Viquez et al.   JOURNAL OF NEUROSCIENCE

α-Synuclein and Its A30P Mutant Affect Actin Cytoskeletal Structure and Dynamics

(2009) Vítor L. Sousa et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular interaction of α-synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells

(2009) R. M. Zhou et al.   MOLECULAR BIOLOGY REPORTS

Genome-wide association study reveals genetic risk underlying Parkinson's disease

(2009) Javier Simón-Sánchez et al.   NATURE GENETICS

Selective detection, quantification, and subcellular location of α-synuclein aggregates with a protein aggregate filtration assay

(2008) Michael L. Kramer et al.   BIOTECHNIQUES

Neuronal programmed cell death induces glial cell division in the adult Drosophila brain

(2008) K. Kato et al.   DEVELOPMENT

Drosophila EGFR signalling is modulated by differential compartmentalization of Rhomboid intramembrane proteases

(2008) Shaul Yogev et al.   EMBO JOURNAL

Emerging pathways in genetic Parkinson’s disease: tangles, Lewy bodies and LRRK2

(2008) Michael J. Devine et al.   FEBS Journal

Dissociation of tau toxicity and phosphorylation: role of GSK-3β, MARK and Cdk5 in a Drosophila model

(2008) Shreyasi Chatterjee et al.   HUMAN MOLECULAR GENETICS

Regulated interactions of the norepineprhine transporter by the actin and microtubule cytoskeletons

(2008) Alexis M. Jeannotte et al.   JOURNAL OF NEUROCHEMISTRY

Synaptic Defects in a Drosophila Model of Congenital Muscular Dystrophy

(2008) Y. P. Wairkar et al.   JOURNAL OF NEUROSCIENCE

Induction of the Phase II Detoxification Pathway Suppresses Neuron Loss in Drosophila Models of Parkinson's Disease

(2008) K. Trinh et al.   JOURNAL OF NEUROSCIENCE

A Drosophila Model of ALS: Human ALS-Associated Mutation in VAP33A Suggests a Dominant Negative Mechanism

(2008) Anuradha Ratnaparkhi et al.   PLoS One

STAT92E is a positive regulator of Drosophila inhibitor of apoptosis 1 (DIAP/1) and protects against radiation-induced apoptosis

(2008) A. Betz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impairment of microtubule system increases α-synuclein aggregation and toxicity

(2007) Myunghye Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS