Contrasting effect of the latency-reversing agents bryostatin-1 and JQ1 on astrocyte-mediated neuroinflammation and brain neutrophil invasion

The contribution of neutrophils to CNS autoimmunity

(2018) Emily R. Pierson et al.   CLINICAL IMMUNOLOGY

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

NETosis in Alzheimer’s Disease

(2017) Enrica Caterina Pietronigro et al.   Frontiers in Immunology

Bryostatin-1 for latent virus reactivation in HIV-infected patients on antiretroviral therapy

(2016) Carolina Gutiérrez et al.   AIDS

HIV-1 Latency-Reversing Agents Prostratin and Bryostatin-1 Induce Blood–Brain Barrier Disruption/Inflammation and Modulate Leukocyte Adhesion/Transmigration

(2016) Clélia Dental et al.   JOURNAL OF IMMUNOLOGY

The role of IL-17 in CNS diseases

(2015) Ari Waisman et al.   ACTA NEUROPATHOLOGICA

Antiretroviral drugs do not interfere with bryostatin-mediated HIV-1 latency reversal

(2015) Marta Martínez-Bonet et al.   ANTIVIRAL RESEARCH

Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations

(2015) Gregory M. Laird et al.   JOURNAL OF CLINICAL INVESTIGATION

Humoral factors in ALS patients during disease progression

(2015) Jared Ehrhart et al.   Journal of Neuroinflammation

Pivotal Roles of GM-CSF in Autoimmunity and Inflammation

(2015) Aoi Shiomi et al.   MEDIATORS OF INFLAMMATION

Neutrophils promote Alzheimer's disease–like pathology and cognitive decline via LFA-1 integrin

(2015) Elena Zenaro et al.   NATURE MEDICINE

Bryostatin activates HIV-1 latent expression in human astrocytes through a PKC and NF-ĸB-dependent mechanism

(2015) Laura Díaz et al.   Scientific Reports

Short-term administration of disulfiram for reversal of latent HIV infection: a phase 2 dose-escalation study

(2015) Julian H Elliott et al.   Lancet HIV

NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis

(2014) Jonathan D. Brown et al.   MOLECULAR CELL

Rapid inflammasome activation in microglia contributes to brain disease in HIV/AIDS

(2014) John G Walsh et al.   Retrovirology

Celastrol ameliorates HIV-1 Tat-induced inflammatory responses via NF-kappaB and AP-1 inhibition and heme oxygenase-1 induction in astrocytes

(2014) Gi Soo Youn et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy

(2014) Julian H. Elliott et al.   PLoS Pathogens

BET Protein Function Is Required for Inflammation: Brd2 Genetic Disruption and BET Inhibitor JQ1 Impair Mouse Macrophage Inflammatory Responses

(2013) A. C. Belkina et al.   JOURNAL OF IMMUNOLOGY

The search for an HIV cure: tackling latent infection

(2013) Stephen J Kent et al.   LANCET INFECTIOUS DISEASES

Reactive Oxygen Species from Human Astrocytes Induced Functional Impairment and Oxidative Damage

(2013) Wen S. Sheng et al.   NEUROCHEMICAL RESEARCH

Current status of chemokines in the adult CNS

(2013) Annabelle Réaux-Le Goazigo et al.   PROGRESS IN NEUROBIOLOGY

Improved Method for the Preparation of a Human Cell-based, Contact Model of the Blood-Brain Barrier

(2013) Be'eri Niego et al.   Jove-Journal of Visualized Experiments

Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4+ T cells from HIV-1-infected HAART-treated patients

(2012) Sophie Bouchat et al.   AIDS

Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog

(2012) Geneviève Doyon et al.   AIDS

Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1

(2012) Tatsuya Saitoh et al.   Cell Host & Microbe

CSF Penetration by Antiretroviral Drugs

(2012) Christine Eisfeld et al.   CNS DRUGS

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

(2012) Liang Shan et al.   IMMUNITY

Interleukin-6, a Major Cytokine in the Central Nervous System

(2012) María Erta et al.   International Journal of Biological Sciences

Leukotrienes inhibit early stages of HIV-1 infection in monocyte-derived microglia-like cells

(2012) Jonathan Bertin et al.   Journal of Neuroinflammation

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

Shock and kill

(2012) Steven G. Deeks   NATURE

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation

(2011) S. Xing et al.   JOURNAL OF VIROLOGY

Bryostatin Modulates Latent HIV-1 Infection via PKC and AMPK Signaling but Inhibits Acute Infection in a Receptor Independent Manner

(2010) Rajeev Mehla et al.   PLoS One

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Suberoylanilide Hydroxamic Acid Reactivates HIV from Latently Infected Cells

(2009) Xavier Contreras et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient magnetic bead-based separation of HIV-1-infected cells using an improved reporter virus system reveals that p53 up-regulation occurs exclusively in the virus-expressing cell population

(2009) Michaël Imbeault et al.   VIROLOGY

Validation of the CNS Penetration-Effectiveness Rank for Quantifying Antiretroviral Penetration Into the Central Nervous System

(2008) Scott Letendre   ARCHIVES OF NEUROLOGY

Hexamethylbisacetamide and Disruption of Human Immunodeficiency Virus Type 1 Latency in CD4+T Cells

(2008) Shailesh K. Choudhary et al.   JOURNAL OF INFECTIOUS DISEASES

Mechanisms of glutamate release from astrocytes

(2007) Erik B. Malarkey et al.   NEUROCHEMISTRY INTERNATIONAL