Brain ureido degenerative protein modifications are associated with neuroinflammation and proteinopathy in Alzheimer’s disease with cerebrovascular disease

Intraneuronal protein aggregation as a trigger for inflammation and neurodegeneration in the aging brain

(2017) Antonio Currais et al.   FASEB JOURNAL

Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls

(2016) Srinivas Ayyadevara et al.   AGING CELL

Citrullination and deamidation affect aggregation properties of amyloid β-proteins

(2016) Dai Osaki et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Plasma proteome coverage is increased by unique peptide recovery from sodium deoxycholate precipitate

(2016) Aida Serra et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Characterization of Glutamine Deamidation by Long-Length Electrostatic Repulsion-Hydrophilic Interaction Chromatography-Tandem Mass Spectrometry (LERLIC-MS/MS) in Shotgun Proteomics

(2016) Aida Serra et al.   ANALYTICAL CHEMISTRY

Ureido group-specific antibodies are induced in rabbits immunized with citrulline- or homocitrulline-containing antigens

(2016) Sanna Turunen et al.   AUTOIMMUNITY

Anti-Hsp90 therapy in autoimmune and inflammatory diseases: a review of preclinical studies

(2016) Stefan Tukaj et al.   CELL STRESS & CHAPERONES

Astrocytic GAP43 Induced by the TLR4/NF- B/STAT3 Axis Attenuates Astrogliosis-Mediated Microglial Activation and Neurotoxicity

(2016) C.-C. Hung et al.   JOURNAL OF NEUROSCIENCE

2016 update of the PRIDE database and its related tools

(2016) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Insight of brain degenerative protein modifications in the pathology of neurodegeneration and dementia by proteomic profiling

(2016) Sunil S. Adav et al.   Molecular Brain

Dementia-linked amyloidosis is associated with brain protein deamidation as revealed by proteomic profiling of human brain tissues

(2016) Sunil S. Adav et al.   Molecular Brain

Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer’s disease with cerebrovascular disease

(2016) Xavier Gallart-Palau et al.   Molecular Brain

Protein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with Dysregulation

(2015) Erin Witalison et al.   CURRENT DRUG TARGETS

TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse

(2015) Bo-Ra Na et al.   JOURNAL OF CELL BIOLOGY

At the Bedside: Neutrophil extracellular traps (NETs) as targets for biomarkers and therapies in autoimmune diseases

(2015) April Barnado et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Promiscuity of autoimmune responses to MBP after stroke

(2015) Dannielle Zierath et al.   JOURNAL OF NEUROIMMUNOLOGY

Dementia warning for the Asia-Pacific region

(2015) The Lancet Neurology   LANCET NEUROLOGY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Multidimensional proteomics for cell biology

(2015) Mark Larance et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein carbamylation is a hallmark of aging

(2015) Laëtitia Gorisse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FunRich: An open access standalone functional enrichment and interaction network analysis tool

(2015) Mohashin Pathan et al.   PROTEOMICS

Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR)

(2015) Xavier Gallart-Palau et al.   Scientific Reports

Protein Carbamylation in Kidney Disease: Pathogenesis and Clinical Implications

(2014) Sahir Kalim et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Identification of a novel myositis-associated antibody directed against cortactin

(2014) Moisés Labrador-Horrillo et al.   AUTOIMMUNITY REVIEWS

Carbamylated low-density lipoprotein induces endothelial dysfunction

(2014) Thimoteus Speer et al.   EUROPEAN HEART JOURNAL

Adducin Is Required for Desmosomal Cohesion in Keratinocytes

(2014) Vera Rötzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relapsing-Remitting Central Nervous System Autoimmunity Mediated by GFAP-Specific CD8 T Cells

(2014) K. Sasaki et al.   JOURNAL OF IMMUNOLOGY

Anti-kelch-like 12 and anti-hexokinase 1: novel autoantibodies in primary biliary cirrhosis

(2014) Gary L. Norman et al.   LIVER INTERNATIONAL

Unconventional post-translational modifications in immunological signaling

(2014) Kerri A Mowen et al.   NATURE IMMUNOLOGY

Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis

(2014) Anca I. Catrina et al.   Nature Reviews Rheumatology

Global Epidemiology of Dementia: Alzheimer’s and Vascular Types

(2014) Liara Rizzi et al.   Biomed Research International

Proteomics of protein post-translational modifications implicated in neurodegeneration

(2014) Ru-Jing Ren et al.   Translational Neurodegeneration

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

The Role of Reticulons in Neurodegenerative Diseases

(2013) Valerio Chiurchiù et al.   NEUROMOLECULAR MEDICINE

Identification and characterization of citrulline-modified brain proteins by combining HCD and CID fragmentation

(2013) Zhicheng Jin et al.   PROTEOMICS

ATP Induces Protein Arginine Deiminase 2-Dependent Citrullination in Mast Cells through the P2X7 Purinergic Receptor

(2012) S. Arandjelovic et al.   JOURNAL OF IMMUNOLOGY

Amyloid deposits: Protection against toxic protein species?

(2011) Sebastian Treusch et al.   CELL CYCLE

PeaksPTM: Mass Spectrometry-Based Identification of Peptides with Unspecified Modifications

(2011) Xi Han et al.   JOURNAL OF PROTEOME RESEARCH

PEAKS DB:De NovoSequencing Assisted Database Search for Sensitive and Accurate Peptide Identification

(2011) Jing Zhang et al.   MOLECULAR & CELLULAR PROTEOMICS

Cellular Strategies of Protein Quality Control

(2011) B. Chen et al.   Cold Spring Harbor Perspectives in Biology

Importance of research on peptidylarginine deiminase and citrullinated proteins in age-related disease

(2010) Akihito Ishigami et al.   Geriatrics & Gerontology International

The P2X7-Egr pathway regulates nucleotide-dependent inflammatory gene expression in microglia

(2010) S. A. Friedle et al.   GLIA

Contribution of Myelin Autoantigen Citrullination to T Cell Autoaggression in the Central Nervous System

(2010) A. Carrillo-Vico et al.   JOURNAL OF IMMUNOLOGY

The Microtubule Regulator Stathmin Is an Endogenous Protein Agonist for TLR3

(2010) M. Bsibsi et al.   JOURNAL OF IMMUNOLOGY

Carbamylation-Dependent Activation of T Cells: A Novel Mechanism in the Pathogenesis of Autoimmune Arthritis

(2010) P. Mydel et al.   JOURNAL OF IMMUNOLOGY

P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways

(2010) Miho Shiratori et al.   JOURNAL OF NEUROCHEMISTRY

Anti-α-Internexin Autoantibody from Neuropsychiatric Lupus Induce Cognitive Damage via Inhibiting Axonal Elongation and Promote Neuron Apoptosis

(2010) Xiao-ye Lu et al.   PLoS One

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Altered proteolytic events in experimental autoimmune encephalomyelitis discovered by iTRAQ shotgun proteomics analysis of spinal cord

(2009) Mohit Jain et al.   Proteome Science

Accumulation of Citrullinated Proteins by Up-Regulated Peptidylarginine Deiminase 2 in Brains of Scrapie-Infected Mice

(2008) Byungki Jang et al.   AMERICAN JOURNAL OF PATHOLOGY

Immunity to Citrullinated Proteins in Rheumatoid Arthritis

(2008) Lars Klareskog et al.   Annual Review of Immunology

Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors

(2008) Raj N Kalaria et al.   LANCET NEUROLOGY

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE