Cholinergic modulation of the hippocampal region and memory function

Cholinergic circuits in cognitive flexibility

(2017) Vania F. Prado et al.   NEUROSCIENCE

Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology

(2016) Benjamin Kolisnyk et al.   CEREBRAL CORTEX

Astrocyte Intermediaries of Septal Cholinergic Modulation in the Hippocampus

(2016) Milan Pabst et al.   NEURON

Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs

(2015) Rajnish Kumar et al.   BRAIN

Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer’s disease

(2015) Alaina Baker-Nigh et al.   BRAIN

α7 nicotinic ACh receptor-deficient mice exhibit sustained attention impairments that are reversed by β2 nicotinic ACh receptor activation

(2015) Benjamin Kolisnyk et al.   BRITISH JOURNAL OF PHARMACOLOGY

Current Practices in the Treatment of Alzheimer Disease: Where is the Evidence After the Phase III Trials?

(2015) Megan J. Ehret et al.   CLINICAL THERAPEUTICS

Synergy of Direct and Indirect Cholinergic Septo-Hippocampal Pathways Coordinates Firing in Hippocampal Networks

(2015) H. Dannenberg et al.   JOURNAL OF NEUROSCIENCE

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

Physiological and neurobehavioral effects of cholinesterase inhibition in healthy adults

(2015) Katherine C. Morasch et al.   PHYSIOLOGY & BEHAVIOR

Attenuation in rats of impairments of memory by scopolamine, a muscarinic receptor antagonist, by mecamylamine, a nicotinic receptor antagonist

(2015) L. A. Newman et al.   PSYCHOPHARMACOLOGY

Nicotinic ACh receptors as therapeutic targets in CNS disorders

(2015) Kelly T. Dineley et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Medial septum regulates the hippocampal spatial representation

(2015) Omar Mamad et al.   Frontiers in Behavioral Neuroscience

An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence

(2015) Silke Frahm et al.   eLife

Corelease of acetylcholine and GABA from cholinergic forebrain neurons

(2015) Arpiar Saunders et al.   eLife

Cumulative Use of Strong Anticholinergics and Incident Dementia

(2015) Shelly L. Gray et al.   JAMA Internal Medicine

Atrophy of the cholinergic basal forebrain in dementia with Lewy bodies and Alzheimer’s disease dementia

(2014) Michel J. Grothe et al.   JOURNAL OF NEUROLOGY

An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats

(2014) Robert Alan Mans et al.   JOURNAL OF NEUROPHYSIOLOGY

Presynaptic  7 Nicotinic Acetylcholine Receptors Enhance Hippocampal Mossy Fiber Glutamatergic Transmission via PKA Activation

(2014) Q. Cheng et al.   JOURNAL OF NEUROSCIENCE

Direct excitation of parvalbumin-positive interneurons by M1muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition

(2014) Feng Yi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Multiple Anticholinergic Medication Use and Risk of Hospital Admission for Confusion or Dementia

(2014) Lisa M. Kalisch Ellett et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Identification of distinct ChAT+ neurons and activity-dependent control of postnatal SVZ neurogenesis

(2014) Patricia Paez-Gonzalez et al.   NATURE NEUROSCIENCE

Optogenetic activation of septal cholinergic neurons suppresses sharp wave ripples and enhances theta oscillations in the hippocampus

(2014) Marie Vandecasteele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

M1 muscarinic acetylcholine receptor in Alzheimer’s disease

(2014) Shangtong Jiang et al.   Neuroscience Bulletin

ChAT-ChR2-EYFP Mice Have Enhanced Motor Endurance But Show Deficits in Attention and Several Additional Cognitive Domains

(2013) B. Kolisnyk et al.   JOURNAL OF NEUROSCIENCE

Forebrain Deletion of the Vesicular Acetylcholine Transporter Results in Deficits in Executive Function, Metabolic, and RNA Splicing Abnormalities in the Prefrontal Cortex

(2013) B. Kolisnyk et al.   JOURNAL OF NEUROSCIENCE

Sleep-dependent memory triage: evolving generalization through selective processing

(2013) Robert Stickgold et al.   NATURE NEUROSCIENCE

Cholinergic basal forebrain atrophy predicts amyloid burden in Alzheimer's disease

(2013) Stefan Teipel et al.   NEUROBIOLOGY OF AGING

Synaptic muscarinic response types in hippocampal CA1 interneurons depend on different levels of presynaptic activity and different muscarinic receptor subtypes

(2013) L. Andrew Bell et al.   NEUROPHARMACOLOGY

About Sleep's Role in Memory

(2013) Björn Rasch et al.   PHYSIOLOGICAL REVIEWS

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice

(2012) Amit Berson et al.   EMBO Molecular Medicine

M2 muscarinic acetylcholine receptors regulate long-term potentiation at hippocampal CA3 pyramidal cell synapses in an input-specific fashion

(2012) Fang Zheng et al.   JOURNAL OF NEUROPHYSIOLOGY

Glutamatergic Synapse Formation is Promoted by  7-Containing Nicotinic Acetylcholine Receptors

(2012) A. F. Lozada et al.   JOURNAL OF NEUROSCIENCE

OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons

(2012) Richardson N Leão et al.   NATURE NEUROSCIENCE

Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior

(2012) Marina R. Picciotto et al.   NEURON

Uncoupling of M1 muscarinic receptor/G-protein interaction by amyloid β1–42

(2012) Helena Janíčková et al.   NEUROPHARMACOLOGY

Dual Effect of Beta-Amyloid on α7 and α4β2 Nicotinic Receptors Controlling the Release of Glutamate, Aspartate and GABA in Rat Hippocampus

(2012) Elisa Mura et al.   PLoS One

Elimination of the vesicular acetylcholine transporter in the forebrain causes hyperactivity and deficits in spatial memory and long-term potentiation

(2012) A. C. Martyn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholinergic modulation of cognitive processing: insights drawn from computational models

(2012) Ehren L. Newman et al.   Frontiers in Behavioral Neuroscience

Reward, Addiction, Withdrawal to Nicotine

(2011) Mariella De Biasi et al.   Annual Review of Neuroscience

Atrophy of the Cholinergic Basal Forebrain Over the Adult Age Range and in Early Stages of Alzheimer's Disease

(2011) Michel Grothe et al.   BIOLOGICAL PSYCHIATRY

Loss of Medial Septum Cholinergic Neurons in THY-Tau22 Mouse Model: What Links with tau Pathology?

(2011) K. Belarbi et al.   Current Alzheimer Research

Habenula “Cholinergic” Neurons Corelease Glutamate and Acetylcholine and Activate Postsynaptic Neurons via Distinct Transmission Modes

(2011) Jing Ren et al.   NEURON

Timing-Dependent Septal Cholinergic Induction of Dynamic Hippocampal Synaptic Plasticity

(2011) Zhenglin Gu et al.   NEURON

Nicotinic excitatory postsynaptic potentials in hippocampal CA1 interneurons are predominantly mediated by nicotinic receptors that contain α4 and β2 subunits

(2011) Karen A. Bell et al.   NEUROPHARMACOLOGY

Recognition of novel objects and their location in rats with selective cholinergic lesion of the medial septum

(2011) Li Cai et al.   NEUROSCIENCE LETTERS

M1 and M4 Receptors Modulate Hippocampal Pyramidal Neurons

(2010) Sameera Dasari et al.   JOURNAL OF NEUROPHYSIOLOGY

RG3487, a Novel Nicotinic  7 Receptor Partial Agonist, Improves Cognition and Sensorimotor Gating in Rodents

(2010) T. L. Wallace et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Differential levels of apolipoprotein E and butyrylcholinesterase show strong association with pathological signs of Alzheimer's disease in the brain in vivo

(2010) Taher Darreh-Shori et al.   NEUROBIOLOGY OF AGING

Cortical α7 Nicotinic Acetylcholine Receptor and β-Amyloid Levels in Early Alzheimer Disease

(2009) Milos D. Ikonomovic et al.   ARCHIVES OF NEUROLOGY

Reduction of Basal Forebrain Cholinergic System Parallels Cognitive Impairment in Patients at High Risk of Developing Alzheimer's Disease

(2009) M. Grothe et al.   CEREBRAL CORTEX

Tonic Modulation of GABA Release by Nicotinic Acetylcholine Receptors in Layer V of the Murine Prefrontal Cortex

(2009) Patrizia Aracri et al.   CEREBRAL CORTEX

Cholinergic Stimulation Enhances Neural Activity Associated with Encoding but Reduces Neural Activity Associated with Retrieval in Humans

(2009) J. Kukolja et al.   JOURNAL OF NEUROSCIENCE

Dissociating  -Amyloid from  7 Nicotinic Acetylcholine Receptor by a Novel Therapeutic Agent, S 24795, Normalizes  7 Nicotinic Acetylcholine and NMDA Receptor Function in Alzheimer's Disease Brain

(2009) H.-Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function

(2009) Edson X. Albuquerque et al.   PHYSIOLOGICAL REVIEWS

Intracellular mechanisms underlying the nicotinic enhancement of LTP in the rat dentate gyrus

(2008) Philip J. Welsby et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Memory loss in Alzheimer’s disease: implications for development of therapeutics

(2008) Carl A Gold et al.   Expert Review of Neurotherapeutics

Modulation of long-term potentiation by individual subtypes of muscarinic acetylcholine receptor in the rat dentate gyrus

(2008) Le Luo et al.   HIPPOCAMPUS

Neuroanatomical and behavioral effects of a novel version of the cholinergic immunotoxin mu p75-saporin in mice

(2008) Pierre-Henri Moreau et al.   HIPPOCAMPUS

Desensitization of Nicotinic Acetylcholine Receptors as a Strategy for Drug Development

(2008) J. J. Buccafusco et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The hippocampus and memory: insights from spatial processing

(2008) Chris M. Bird et al.   NATURE REVIEWS NEUROSCIENCE

It is not “either/or”: Activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood

(2007) M PICCIOTTO et al.   PROGRESS IN NEUROBIOLOGY