An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence

The habenulo-interpeduncular pathway in nicotine aversion and withdrawal

(2015) Beatriz Antolin-Fontes et al.   NEUROPHARMACOLOGY

Synaptic vesicle recycling: steps and principles

(2014) S. O. Rizzoli   EMBO JOURNAL

Conserved expression of the GPR151 receptor in habenular axonal projections of vertebrates

(2014) Jonas Broms et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Vesicular Glutamate Transporters Use Flexible Anion and Cation Binding Sites for Efficient Accumulation of Neurotransmitter

(2014) Julia Preobraschenski et al.   NEURON

GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment

(2014) S. J. Shabel et al.   SCIENCE

Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis

(2014) Nicolas X Tritsch et al.   eLife

Activation of GABAergic Neurons in the Interpeduncular Nucleus Triggers Physical Nicotine Withdrawal Symptoms

(2013) Rubing Zhao-Shea et al.   CURRENT BIOLOGY

Vesicular glutamate transporter-3 in the rodent brain: Vesicular colocalization with vesicular γ-aminobutyric acid transporter

(2013) M.J. Stensrud et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse

(2013) Kia J. Jackson et al.   NEUROPHARMACOLOGY

Reexposure to nicotine during withdrawal increases the pacemaking activity of cholinergic habenular neurons

(2013) A. Gorlich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of α5* nicotinic acetylcholine receptors in the effects of acute and chronic nicotine treatment on brain reward function in mice

(2013) Christie D. Fowler et al.   PSYCHOPHARMACOLOGY

Translational Research in Nicotine Dependence

(2013) J. R. Turner et al.   Cold Spring Harbor Perspectives in Medicine

Molecular characterization of the subnuclei in rat habenula

(2012) Hidenori Aizawa et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Quantitative Regional and Ultrastructural Localization of the Cav2.3 Subunit of R-type Calcium Channel in Mouse Brain

(2012) L. K. Parajuli et al.   JOURNAL OF NEUROSCIENCE

A Preferentially Segregated Recycling Vesicle Pool of Limited Size Supports Neurotransmission in Native Central Synapses

(2012) Vincenzo Marra et al.   NEURON

Acetylcholine as a Neuromodulator: Cholinergic Signaling Shapes Nervous System Function and Behavior

(2012) Marina R. Picciotto et al.   NEURON

Haplotypes with Copy Number and Single Nucleotide Polymorphisms in CYP2A6 Locus Are Associated with Smoking Quantity in a Japanese Population

(2012) Natsuhiko Kumasaka et al.   PLoS One

Extrasynaptic Neurotransmission as a Way of Modulating Neuronal Functions

(2012) Francisco F. De-Miguel et al.   Frontiers in Physiology

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Reward, Addiction, Withdrawal to Nicotine

(2011) Mariella De Biasi et al.   Annual Review of Neuroscience

Neurotransmitter Corelease: Mechanism and Physiological Role

(2011) Thomas S. Hnasko et al.   Annual Review of Physiology

Immunogold Detection of L-glutamate and D-serine in Small Synaptic-Like Microvesicles in Adult Hippocampal Astrocytes

(2011) L.H. Bergersen et al.   CEREBRAL CORTEX

Habenular α5 nicotinic receptor subunit signalling controls nicotine intake

(2011) Christie D. Fowler et al.   NATURE

From glutamate co-release to vesicular synergy: vesicular glutamate transporters

(2011) Salah El Mestikawy et al.   NATURE REVIEWS NEUROSCIENCE

Habenula “Cholinergic” Neurons Corelease Glutamate and Acetylcholine and Activate Postsynaptic Neurons via Distinct Transmission Modes

(2011) Jing Ren et al.   NEURON

Aversion to Nicotine Is Regulated by the Balanced Activity of β4 and α5 Nicotinic Receptor Subunits in the Medial Habenula

(2011) Silke Frahm et al.   NEURON

Functional Implications of Glutamatergic Projections to the Ventral Tegmental Area

(2011) Stefanie Geisler et al.   REVIEWS IN THE NEUROSCIENCES

Elimination of the Vesicular Acetylcholine Transporter in the Striatum Reveals Regulation of Behaviour by Cholinergic-Glutamatergic Co-Transmission

(2011) Monica S. Guzman et al.   PLOS BIOLOGY

Replication and extension of association of choline acetyltransferase with nicotine dependence in European and African American smokers

(2010) Jinxue Wei et al.   HUMAN GENETICS

Synaptic and Vesicular Coexistence of VGLUT and VGAT in Selected Excitatory and Inhibitory Synapses

(2010) J.-F. Zander et al.   JOURNAL OF NEUROSCIENCE

Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

(2010) Thorgeir E Thorgeirsson et al.   NATURE GENETICS

Nicotine addiction and nicotinic receptors: lessons from genetically modified mice

(2010) Jean-Pierre Changeux   NATURE REVIEWS NEUROSCIENCE

Vesicular Glutamate Transport Promotes Dopamine Storage and Glutamate Corelease In Vivo

(2010) Thomas S. Hnasko et al.   NEURON

Convergent Evidence that Choline Acetyltransferase Gene Variation is Associated with Prospective Smoking Cessation and Nicotine Dependence

(2010) Riju Ray et al.   NEUROPSYCHOPHARMACOLOGY

Distribution and role of Kv3.1b in neurons in the medial septum diagonal band complex

(2010) Z. Henderson et al.   NEUROSCIENCE

The CHRNA5-CHRNA3-CHRNB4 Nicotinic Receptor Subunit Gene Cluster Affects Risk for Nicotine Dependence in African-Americans and in European-Americans

(2009) N. L. Saccone et al.   CANCER RESEARCH

Pedunculopontine and laterodorsal tegmental nuclei contain distinct populations of cholinergic, glutamatergic and GABAergic neurons in the rat

(2009) Hui-Ling Wang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Nicotinic Receptors in the Habenulo-Interpeduncular System Are Necessary for Nicotine Withdrawal in Mice

(2009) R. Salas et al.   JOURNAL OF NEUROSCIENCE

Brn3a and Nurr1 Mediate a Gene Regulatory Pathway for Habenula Development

(2009) L. A. Quina et al.   JOURNAL OF NEUROSCIENCE

Rodent Habenulo-Interpeduncular Pathway Expresses a Large Variety of Uncommon nAChR Subtypes, But Only the  3 4 and  3 3 4 Subtypes Mediate Acetylcholine Release

(2009) S. R. Grady et al.   JOURNAL OF NEUROSCIENCE

Phasic acetylcholine release and the volume transmission hypothesis: time to move on

(2009) Martin Sarter et al.   NATURE REVIEWS NEUROSCIENCE

The glutamate homeostasis hypothesis of addiction

(2009) Peter W. Kalivas   NATURE REVIEWS NEUROSCIENCE

Nicotinic modulation of synaptic transmission and plasticity in cortico-limbic circuits

(2009) Huibert D. Mansvelder et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Projections from basal forebrain to prefrontal cortex comprise cholinergic, GABAergic and glutamatergic inputs to pyramidal cells or interneurons

(2008) Pablo Henny et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone

(2008) Christelle Gras et al.   NATURE NEUROSCIENCE

Presynaptic glutamate receptors: physiological functions and mechanisms of action

(2008) Paulo S. Pinheiro et al.   NATURE REVIEWS NEUROSCIENCE