Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals
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Title
Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 29, Pages 10654-10659
Publisher
Proceedings of the National Academy of Sciences
Online
2014-07-08
DOI
10.1073/pnas.1403521111
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- (2013) P. F. Chinnery et al. BRITISH MEDICAL BULLETIN
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- (2012) Eric A. Schon et al. NATURE REVIEWS GENETICS
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- (2011) Domenico Simone et al. BMC GENOMICS
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- The timing of mitochondrial DNA mutations in aging
- (2011) Konstantin Khrapko NATURE GENETICS
- Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations
- (2011) Brendan A I Payne et al. NATURE GENETICS
- Dynamics of mitochondrial heteroplasmy in three families investigated via a repeatable re-sequencing study
- (2011) Hiroki Goto et al. GENOME BIOLOGY
- Detecting Heteroplasmy from High-Throughput Sequencing of Complete Human Mitochondrial DNA Genomes
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- Investigation of Heteroplasmy in the Human Mitochondrial DNA Control Region: A Synthesis of Observations from More Than 5000 Global Population Samples
- (2009) Jodi A. Irwin et al. JOURNAL OF MOLECULAR EVOLUTION
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