Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 111, Issue 29, Pages 10654-10659
Publisher
Proceedings of the National Academy of Sciences
Online
2014-07-08
DOI
10.1073/pnas.1403521111
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mitochondrial genetics
- (2013) P. F. Chinnery et al. BRITISH MEDICAL BULLETIN
- Hereditary mtDNA Heteroplasmy: A Baseline for Aging?
- (2013) Michael Keogh et al. Cell Metabolism
- Germline mitochondrial DNA mutations aggravate ageing and can impair brain development
- (2013) Jaime M. Ross et al. NATURE
- Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage
- (2013) Scott R. Kennedy et al. PLoS Genetics
- Heteroplasmy of Mouse mtDNA Is Genetically Unstable and Results in Altered Behavior and Cognition
- (2012) Mark S. Sharpley et al. CELL
- Universal heteroplasmy of human mitochondrial DNA
- (2012) B. A. I. Payne et al. HUMAN MOLECULAR GENETICS
- Mitochondrial genomes gleaned from human whole-exome sequencing
- (2012) Ernesto Picardi et al. NATURE METHODS
- Human mitochondrial DNA: roles of inherited and somatic mutations
- (2012) Eric A. Schon et al. NATURE REVIEWS GENETICS
- Spectrum of somatic mitochondrial mutations in five cancers
- (2012) T. C. Larman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Next-Generation Sequencing of Human Mitochondrial Reference Genomes Uncovers High Heteroplasmy Frequency
- (2012) Maria Ximena Sosa et al. PLoS Computational Biology
- A new approach for detecting low-level mutations in next-generation sequence data
- (2012) Mingkun Li et al. GENOME BIOLOGY
- Comparing Phylogeny and the Predicted Pathogenicity of Protein Variations Reveals Equal Purifying Selection across the Global Human mtDNA Diversity
- (2011) Luísa Pereira et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The reference human nuclear mitochondrial sequences compilation validated and implemented on the UCSC genome browser
- (2011) Domenico Simone et al. BMC GENOMICS
- Neutral mitochondrial heteroplasmy and the influence of aging
- (2011) Neal Sondheimer et al. HUMAN MOLECULAR GENETICS
- The timing of mitochondrial DNA mutations in aging
- (2011) Konstantin Khrapko NATURE GENETICS
- Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations
- (2011) Brendan A I Payne et al. NATURE GENETICS
- Dynamics of mitochondrial heteroplasmy in three families investigated via a repeatable re-sequencing study
- (2011) Hiroki Goto et al. GENOME BIOLOGY
- Detecting Heteroplasmy from High-Throughput Sequencing of Complete Human Mitochondrial DNA Genomes
- (2010) Mingkun Li et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Fast and SNP-tolerant detection of complex variants and splicing in short reads
- (2010) T. D. Wu et al. BIOINFORMATICS
- No relationship found between point heteroplasmy in mitochondrial DNA control region and age range, sex and haplogroup in human hairs
- (2010) Maria Angélica de Camargo et al. MOLECULAR BIOLOGY REPORTS
- Heteroplasmic mitochondrial DNA mutations in normal and tumour cells
- (2010) Yiping He et al. NATURE
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- A method and server for predicting damaging missense mutations
- (2010) Ivan A Adzhubei et al. NATURE METHODS
- Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock
- (2009) Pedro Soares et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Automated inference of molecular mechanisms of disease from amino acid substitutions
- (2009) B. Li et al. BIOINFORMATICS
- Investigation of Heteroplasmy in the Human Mitochondrial DNA Control Region: A Synthesis of Observations from More Than 5000 Global Population Samples
- (2009) Jodi A. Irwin et al. JOURNAL OF MOLECULAR EVOLUTION
- Pathogenic Mitochondrial DNA Mutations Are Common in the General Population
- (2008) Hannah R. Elliott et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Mechanisms of formation and accumulation of mitochondrial DNA deletions in aging neurons
- (2008) Hirokazu Fukui et al. HUMAN MOLECULAR GENETICS
- Prevalence of mitochondrial DNA disease in adults
- (2007) Andrew M. Schaefer et al. ANNALS OF NEUROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now