Metabolic impact of glucagon deficiency

Glucagon receptor antagonist-mediated improvements in glycemic control are dependent on functional pancreatic GLP-1 receptor

(2010) Wei Gu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Partial loss of pancreas endocrine and exocrine cells of human ARX-null mutation: Consideration of pancreas differentiation

(2010) Masayuki Itoh et al.   DIFFERENTIATION

Glucagon-Like Peptide-1 Receptor Knockout Mice Are Protected from High-Fat Diet-Induced Insulin Resistance

(2010) Julio E. Ayala et al.   ENDOCRINOLOGY

Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway

(2010) Nitika Arora Gupta et al.   HEPATOLOGY

Pax6 Controls the Expression of Critical Genes Involved in Pancreatic α Cell Differentiation and Function

(2010) Yvan Gosmain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PCSK2-null mice exhibit delayed intestinal motility, reduced refeeding response and altered plasma levels of several regulatory peptides

(2010) Jeffrey Gagnon et al.   LIFE SCIENCES

Glucagon Deficiency Reduces Hepatic Glucose Production and Improves Glucose Tolerance In Adult Mice

(2010) Aidan S. Hancock et al.   MOLECULAR ENDOCRINOLOGY

Serotonin regulates pancreatic beta cell mass during pregnancy

(2010) Hail Kim et al.   NATURE MEDICINE

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

(2010) Eric E Zhang et al.   NATURE MEDICINE

CRTC2 (TORC2) Contributes to the Transcriptional Response to Fasting in the Liver but Is Not Required for the Maintenance of Glucose Homeostasis

(2009) John Le Lay et al.   Cell Metabolism

Minireview: Estrogenic Protection of β-Cell Failure in Metabolic Diseases

(2009) Suhuan Liu et al.   ENDOCRINOLOGY

The Circadian Clock Components CRY1 and CRY2 Are Necessary to Sustain Sex Dimorphism in Mouse Liver Metabolism

(2009) Isabelle M. Bur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Extrapancreatic Effects of Glucagon-Like Peptide-1 and Related Peptides

(2009) Rania Abu-Hamdah et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hepatic energy state is regulated by glucagon receptor signaling in mice

(2009) Eric D. Berglund et al.   JOURNAL OF CLINICAL INVESTIGATION

Mice Deficient for Glucagon Gene-Derived Peptides Display Normoglycemia and Hyperplasia of Islet α-Cells But Not of Intestinal L-Cells

(2009) Yoshitaka Hayashi et al.   MOLECULAR ENDOCRINOLOGY

The Transcriptional Response of the Islet to Pregnancy in Mice

(2009) Sebastian Rieck et al.   MOLECULAR ENDOCRINOLOGY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Homozygous P86S Mutation of the Human Glucagon Receptor Is Associated With Hyperglucagonemia, α Cell Hyperplasia, and Islet Cell Tumor

(2009) Cuiqi Zhou et al.   PANCREAS

SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats

(2009) D. M. Erion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoid regulation of preproglucagon transcription and RNA stability during stress

(2009) R. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Glucagon Receptor Is Required for the Adaptive Metabolic Response to Fasting

(2008) Christine Longuet et al.   Cell Metabolism

On the origin of the   cell

(2008) J. M. Oliver-Krasinski et al.   GENES & DEVELOPMENT

Glucagon Cell Adenomatosis: A Newly Recognized Disease of the Endocrine Pancreas

(2008) Tobias Henopp et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

(2008) Yi Liu et al.   NATURE

Nesidioblastosis and Hyperplasia of ?? Cells, Microglucagonoma, and Nonfunctioning Islet Cell Tumor of the Pancreas

(2008) Run Yu et al.   PANCREAS

Interleukin-6 regulates pancreatic  -cell mass expansion

(2008) H. Ellingsgaard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

(2008) N. Gustavsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA