Nuclear receptors regulate lipid metabolism and oxidative stress markers in chondrocytes

Suppression of REDD1 in osteoarthritis cartilage, a novel mechanism for dysregulated mTOR signaling and defective autophagy

(2016) O. Alvarez-Garcia et al.   OSTEOARTHRITIS AND CARTILAGE

Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage

(2015) Shabana Amanda Ali et al.   Arthritis & Rheumatology

Repeated Exposure to High-Frequency Low-Amplitude Vibration Induces Degeneration of Murine Intervertebral Discs and Knee Joints

(2015) Matthew R. McCann et al.   Arthritis & Rheumatology

Peroxisome Proliferator-Activated Receptor δ Promotes the Progression of Posttraumatic Osteoarthritis in a Mouse Model

(2015) A. Ratneswaran et al.   Arthritis & Rheumatology

Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury

(2014) Chia-Lung Wu et al.   ANNALS OF THE RHEUMATIC DISEASES

Involvement of Angiopoietin-like 4 in Matrix Remodeling during Chondrogenic Differentiation of Mesenchymal Stem Cells

(2014) Marc Mathieu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of epidermal fatty acid binding protein (E-FABP) in septoclasts in the growth plate cartilage of mice

(2014) Yasuhiko Bando et al.   JOURNAL OF MOLECULAR HISTOLOGY

Liver X Receptor activation delays chondrocyte hypertrophy during endochondral bone growth

(2014) M.M.-G. Sun et al.   OSTEOARTHRITIS AND CARTILAGE

Disturbed Cartilage and Joint Homeostasis Resulting From a Loss of Mitogen-Inducible Gene 6 in a Mouse Model of Joint Dysfunction

(2014) Michael A. Pest et al.   Arthritis & Rheumatology

Adult Cartilage-Specific Peroxisome Proliferator–Activated Receptor Gamma Knockout Mice Exhibit the Spontaneous Osteoarthritis Phenotype

(2013) Faezeh Vasheghani et al.   AMERICAN JOURNAL OF PATHOLOGY

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

(2013) Islam N. Mohamed et al.   DIABETOLOGIA

Unfolded Protein Response Signaling and Metabolic Diseases

(2013) Jaemin Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative stress and protein carbonylation in adipose tissue — Implications for insulin resistance and diabetes mellitus

(2013) Tatjana Ruskovska et al.   Journal of Proteomics

Regulation of energy metabolism by long-chain fatty acids

(2013) Manabu T. Nakamura et al.   PROGRESS IN LIPID RESEARCH

Inhibition of inducible nitric oxide synthase prevents lipid peroxidation in osteoarthritic chondrocytes

(2012) Mireille Bentz et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cytoprotective and anti-inflammatory effects of melatonin in hydrogen peroxide-stimulated CHON-001 human chondrocyte cell line and rabbit model of osteoarthritis via the SIRT1 pathway

(2012) Hyun-Dae Lim et al.   JOURNAL OF PINEAL RESEARCH

Metabolic syndrome meets osteoarthritis

(2012) Qi Zhuo et al.   Nature Reviews Rheumatology

Epidemiology of Osteoarthritis

(2012) Tuhina Neogi et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Association of cartilage-specific deletion of peroxisome proliferator-activated receptor γ with abnormal endochondral ossification and impaired cartilage growth and development in a murine model

(2011) Roxana Monemdjou et al.   ARTHRITIS AND RHEUMATISM

Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: Effects of short-term exercise

(2011) Timothy M. Griffin et al.   ARTHRITIS AND RHEUMATISM

Interactions of glutathione transferases with 4-hydroxynonenal

(2011) Larissa M. Balogh et al.   DRUG METABOLISM REVIEWS

The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue

(2011) Lee D Roberts et al.   GENOME BIOLOGY

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis

(2010) C. Karlsson et al.   OSTEOARTHRITIS AND CARTILAGE

LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model

(2010) Ning Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: implication in osteoarthritis pathogenesis

(2010) Rana El-Bikai et al.   ARTHRITIS RESEARCH & THERAPY

The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle

(2009) Lin Piao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Rho/ROCK and MEK/ERK activation by transforming growth factor-α induces articular cartilage degradation

(2009) C Thomas G Appleton et al.   LABORATORY INVESTIGATION

Global analysis of nuclear receptor expression and dysregulation in human osteoarthritic articular cartilage

(2009) L.A. Collins-Racie et al.   OSTEOARTHRITIS AND CARTILAGE

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

(2008) Jérôme N. Feige et al.   Cell Metabolism

Hypoxia upregulates the expression of angiopoietin-like-4 in human articular chondrocytes: Role of angiopoietin-like-4 in the expression of matrix metalloproteinases and cartilage degradation

(2008) Minako Murata et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase

(2008) France Vaillancourt et al.   ARTHRITIS RESEARCH & THERAPY