Downregulation of miR-221-3p contributes to IL-1β-induced cartilage degradation by directly targeting the SDF1/CXCR4 signaling pathway
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Title
Downregulation of miR-221-3p contributes to IL-1β-induced cartilage degradation by directly targeting the SDF1/CXCR4 signaling pathway
Authors
Keywords
Osteoarthritis, miR-221-3p, Il-1β, SDF1/CXCR4 signaling pathway
Journal
JOURNAL OF MOLECULAR MEDICINE-JMM
Volume 95, Issue 6, Pages 615-627
Publisher
Springer Nature
Online
2017-02-24
DOI
10.1007/s00109-017-1516-6
References
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- Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression
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- (2010) David J. Hunter Nature Reviews Rheumatology
- Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
- (2010) Mohit Kapoor et al. Nature Reviews Rheumatology
- Expression of MicroRNA-146a in osteoarthritis cartilage
- (2009) Keiichiro Yamasaki et al. ARTHRITIS AND RHEUMATISM
- Gene Regulation by Transcription Factors and MicroRNAs
- (2008) O. Hobert SCIENCE
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