Zika virus: An emerging flavivirus

Zika: the origin and spread of a mosquito-borne virus

(2016) Mary Kay Kindhauser et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

From Mosquitos to Humans: Genetic Evolution of Zika Virus

(2016) Lulan Wang et al.   Cell Host & Microbe

Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody

(2016) Lianpan Dai et al.   Cell Host & Microbe

Zika Virus

(2016) Didier Musso et al.   CLINICAL MICROBIOLOGY REVIEWS

Contribution of intertwined loop to membrane association revealed by Zika virus full‐length NS1 structure

(2016) Xiaoying Xu et al.   EMBO JOURNAL

Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016

(2016) Luisa Barzon et al.   Eurosurveillance

Zika virus complete genome from Salvador, Bahia, Brazil

(2016) Marta Giovanetti et al.   INFECTION GENETICS AND EVOLUTION

Comparison of the live-attenuated Japanese encephalitis vaccine SA14 -14-2 strain with its pre-attenuated virulent parent SA14 strain: similarities and differences in vitro and in vivo

(2016) Sang-Im Yun et al.   JOURNAL OF GENERAL VIROLOGY

Phylogenetic analysis of the NS5 gene of Zika virus

(2016) Rama Adiga   JOURNAL OF MEDICAL VIROLOGY

Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens Mosquitoes

(2016) G. P. Göertz et al.   JOURNAL OF VIROLOGY

Zika virus infection in French Polynesia

(2016) Jean-Marie Jouannic et al.   LANCET

Microcephaly in Brazil: how to interpret reported numbers?

(2016) Cesar Gomes Victora et al.   LANCET

Anticipating the international spread of Zika virus from Brazil

(2016) Isaac I Bogoch et al.   LANCET

Association between Zika virus and microcephaly in French Polynesia, 2013–15: a retrospective study

(2016) Simon Cauchemez et al.   LANCET

Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study

(2016) Van-Mai Cao-Lormeau et al.   LANCET

Guillain–Barré Syndrome (42 Cases) Occurring During a Zika Virus Outbreak in French Polynesia

(2016) Louise Watrin et al.   MEDICINE

Ultrastructure of Zika virus particles in cell cultures

(2016) Debora Ferreira Barreto-Vieira et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Structural basis of potent Zika–dengue virus antibody cross-neutralization

(2016) Giovanna Barba-Spaeth et al.   NATURE

Structure of the NS3 helicase from Zika virus

(2016) Rinku Jain et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Zika virus NS1 structure reveals diversity of electrostatic surfaces among flaviviruses

(2016) Hao Song et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Zika Virus Associated with Microcephaly

(2016) Jernej Mlakar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus in the Americas — Yet Another Arbovirus Threat

(2016) Anthony S. Fauci et al.   NEW ENGLAND JOURNAL OF MEDICINE

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

(2016) Jian Lei et al.   SCIENCE

Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease

(2016) B. M. Akiyama et al.   SCIENCE

Crystal structure of unlinked NS2B-NS3 protease from Zika virus

(2016) Zhenzhen Zhang et al.   SCIENCE

Assessing the global threat from Zika virus

(2016) J. Lessler et al.   SCIENCE

Zika virus in the Americas: Early epidemiological and genetic findings

(2016) N. R. Faria et al.   SCIENCE

The 3.8 A resolution cryo-EM structure of Zika virus

(2016) D. Sirohi et al.   SCIENCE

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection

(2016) K. Stettler et al.   SCIENCE

RNA Structure Duplications and Flavivirus Host Adaptation

(2016) Sergio M. Villordo et al.   TRENDS IN MICROBIOLOGY

Standing your ground to exoribonucleases: Function of Flavivirus long non-coding RNAs

(2016) Phillida A. Charley et al.   VIRUS RESEARCH

Structure of the NS2B-NS3 protease from Zika virus after self-cleavage

(2016) Wint Wint Phoo et al.   Nature Communications

Structure of the NS3 helicase from Zika virus

(2016) Rinku Jain et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Zika virus NS1 structure reveals diversity of electrostatic surfaces among flaviviruses

(2016) Hao Song et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structures of NS5 Methyltransferase from Zika Virus

(2016) Javier Coloma et al.   Cell Reports

Zika Virus Outbreak in Haiti in 2014: Molecular and Clinical Data

(2016) John Lednicky et al.   PLoS Neglected Tropical Diseases

Comparative genomic analysis of pre-epidemic and epidemic Zika virus strains for virological factors potentially associated with the rapidly expanding epidemic

(2016) Zheng Zhu et al.   Emerging Microbes & Infections

Possible Association Between Zika Virus Infection and Microcephaly — Brazil, 2015

(2016) Lavinia Schuler-Faccini et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Zika Virus Spreads to New Areas — Region of the Americas, May 2015–January 2016

(2016) Morgan Hennessey et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Detection of Zika Virus Infection in Thailand, 2012–2014

(2015) Rome Buathong et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A report on the outbreak of Zika virus on Easter Island, South Pacific, 2014

(2015) J. Tognarelli et al.   ARCHIVES OF VIROLOGY

Zika virus infection in a traveller returning to Europe from Brazil, March 2015

(2015) L Zammarchi et al.   Eurosurveillance

Scanning Mutagenesis Studies Reveal a Potential Intramolecular Interaction within the C-Terminal Half of Dengue Virus NS2A Involved in Viral RNA Replication and Virus Assembly and Secretion

(2015) Ren-Huang Wu et al.   JOURNAL OF VIROLOGY

Biology of Zika Virus Infection in Human Skin Cells

(2015) Rodolphe Hamel et al.   JOURNAL OF VIROLOGY

Zika virus: following the path of dengue and chikungunya?

(2015) Didier Musso et al.   LANCET

First report of autochthonous transmission of Zika virus in Brazil

(2015) Camila Zanluca et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness

(2015) G. Manokaran et al.   SCIENCE

Viral membrane fusion

(2015) Stephen C. Harrison   VIROLOGY

Flavivirus sfRNA suppresses antiviral RNA interference in cultured cells and mosquitoes and directly interacts with the RNAi machinery

(2015) Stephanie L. Moon et al.   VIROLOGY

Functions of the 3′ and 5′ genome RNA regions of members of the genus Flavivirus

(2015) Margo A. Brinton et al.   VIRUS RESEARCH

Functional non-coding RNAs derived from the flavivirus 3′ untranslated region

(2015) B.D. Clarke et al.   VIRUS RESEARCH

Flaviviral Replication Complex: Coordination between RNA Synthesis and 5’-RNA Capping

(2015) Valerie Klema et al.   Viruses-Basel

Dengue Virus NS Proteins Inhibit RIG-I/MAVS Signaling by Blocking TBK1/IRF3 Phosphorylation: Dengue Virus Serotype 1 NS4A Is a Unique Interferon-Regulating Virulence Determinant

(2015) Nadine A. Dalrymple et al.   mBio

Dengue Virus RNA Structure Specialization Facilitates Host Adaptation

(2015) Sergio M. Villordo et al.   PLoS Pathogens

First Case of Zika Virus Infection in a Returning Canadian Traveler

(2014) Kevin Fonseca et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Flaviviral RNAs: weapons and targets in the war between virus and host

(2014) Katell Bidet et al.   BIOCHEMICAL JOURNAL

Rapid spread of emerging Zika virus in the Pacific area

(2014) D. Musso et al.   CLINICAL MICROBIOLOGY AND INFECTION

Concurrent outbreaks of dengue, chikungunya and Zika virus infections – an unprecedented epidemic wave of mosquito-borne viruses in the Pacific 2012–2014

(2014) A Roth et al.   Eurosurveillance

First case of laboratory-confirmed Zika virus infection imported into Europe, November 2013

(2014) D Tappe et al.   Eurosurveillance

Evidence of perinatal transmission of Zika virus, French Polynesia, December 2013 and February 2014

(2014) M Besnard et al.   Eurosurveillance

Zika virus infection complicated by Guillain-Barré syndrome – case report, French Polynesia, December 2013

(2014) E Oehler et al.   Eurosurveillance

Flavivirus RNA methylation

(2014) H. Dong et al.   JOURNAL OF GENERAL VIROLOGY

Two Distinct Sets of NS2A Molecules Are Responsible for Dengue Virus RNA Synthesis and Virion Assembly

(2014) Xuping Xie et al.   JOURNAL OF VIROLOGY

Dengue Virus- and Hepatitis C Virus-Induced Replication and Assembly Compartments: the Enemy Inside--Caught in the Web

(2014) L. Chatel-Chaix et al.   JOURNAL OF VIROLOGY

Emerging arboviruses in the Pacific

(2014) Van-Mai Cao-Lormeau et al.   LANCET

Induction of Endoplasmic Reticulum-Derived Replication-Competent Membrane Structures by West Nile Virus Non-Structural Protein 4B

(2014) Pakieli H. Kaufusi et al.   PLoS One

Molecular Characterization of Three Zika Flaviviruses Obtained from Sylvatic Mosquitoes in the Central African Republic

(2014) Nicolas Berthet et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Noncoding Subgenomic Flavivirus RNA: Multiple Functions in West Nile Virus Pathogenesis and Modulation of Host Responses

(2014) Justin Roby et al.   Viruses-Basel

Coupling of replication and assembly in flaviviruses

(2014) Swapna Apte-Sengupta et al.   Current Opinion in Virology

Flavivirus RNAi suppression: decoding non-coding RNA

(2014) Gorben P Pijlman   Current Opinion in Virology

Regulation of Flavivirus RNA synthesis and replication

(2014) Barbara Selisko et al.   Current Opinion in Virology

G3BP1, G3BP2 and CAPRIN1 Are Required for Translation of Interferon Stimulated mRNAs and Are Targeted by a Dengue Virus Non-coding RNA

(2014) Katell Bidet et al.   PLoS Pathogens

RNA structures that resist degradation by Xrn1 produce a pathogenic Dengue virus RNA

(2014) Erich G Chapman et al.   eLife

Zika Virus Infection Acquired During Brief Travel to Indonesia

(2013) Jason C. Kwong et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Membrane curvature in flaviviruses

(2013) Wei Zhang et al.   JOURNAL OF STRUCTURAL BIOLOGY

Novel cis-Acting Element within the Capsid-Coding Region Enhances Flavivirus Viral-RNA Replication by Regulating Genome Cyclization

(2013) Z.-Y. Liu et al.   JOURNAL OF VIROLOGY

Identification of cis-Acting Nucleotides and a Structural Feature in West Nile Virus 3'-Terminus RNA That Facilitate Viral Minus Strand RNA Synthesis

(2013) W. G. Davis et al.   JOURNAL OF VIROLOGY

Japanese encephalitis virus non-coding RNA inhibits activation of interferon by blocking nuclear translocation of interferon regulatory factor 3

(2013) Ruey-Yi Chang et al.   VETERINARY MICROBIOLOGY

Dengue virus subgenomic RNA induces apoptosis through the Bcl-2-mediated PI3k/Akt signaling pathway

(2013) Yi Liu et al.   VIROLOGY

Replication Cycle and Molecular Biology of the West Nile Virus

(2013) Margo Brinton   Viruses-Basel

Flavivirus Entry Receptors: An Update

(2013) Manuel Perera-Lecoin et al.   Viruses-Basel

Flaviviruses: braking the entering

(2013) Theodore C Pierson et al.   Current Opinion in Virology

A single nucleotide mutation in NS2A of Japanese encephalitis-live vaccine virus (SA14-14-2) ablates NS1' formation and contributes to attenuation

(2012) Q. Ye et al.   JOURNAL OF GENERAL VIROLOGY

West Nile Virus Noncoding Subgenomic RNA Contributes to Viral Evasion of the Type I Interferon-Mediated Antiviral Response

(2012) A. Schuessler et al.   JOURNAL OF VIROLOGY

Noncoding Flavivirus RNA Displays RNA Interference Suppressor Activity in Insect and Mammalian Cells

(2012) E. Schnettler et al.   JOURNAL OF VIROLOGY

Cryo-EM structure of the mature dengue virus at 3.5-Å resolution

(2012) Xiaokang Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stability

(2012) S. L. Moon et al.   RNA

Innate Immunity Evasion by Dengue Virus

(2012) Juliet Morrison et al.   Viruses-Basel

Degrees of maturity: the complex structure and biology of flaviviruses

(2012) Theodore C Pierson et al.   Current Opinion in Virology

Genetic Characterization of Zika Virus Strains: Geographic Expansion of the Asian Lineage

(2012) Andrew D. Haddow et al.   PLoS Neglected Tropical Diseases

Flavivirus NS4A-induced Autophagy Protects Cells against Death and Enhances Virus Replication

(2011) Jeffrey E. McLean et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

(2011) Roland Züst et al.   NATURE IMMUNOLOGY

NF90 Binds the Dengue Virus RNA 3′ Terminus and Is a Positive Regulator of Dengue Virus Replication

(2011) Raúl C. Gomila et al.   PLoS One

Dynamic RNA structures in the dengue virus genome

(2011) Nestor G. Iglesias et al.   RNA Biology

Small noncoding RNA modulates japanese encephalitis virus replication and translation in trans

(2011) Yi-Hsin Fan et al.   Virology Journal

Functional RNA Elements in the Dengue Virus Genome

(2011) Leopoldo G. Gebhard et al.   Viruses-Basel

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

In Vitro Reconstitution Reveals Key Intermediate States of Trimer Formation by the Dengue Virus Membrane Fusion Protein

(2010) M. Liao et al.   JOURNAL OF VIROLOGY

The 5' and 3' Downstream AUG Region Elements Are Required for Mosquito-Borne Flavivirus RNA Replication

(2010) P. Friebe et al.   JOURNAL OF VIROLOGY

RNA Structures Required for Production of Subgenomic Flavivirus RNA

(2010) A. Funk et al.   JOURNAL OF VIROLOGY

Interplay of RNA Elements in the Dengue Virus 5' and 3' Ends Required for Viral RNA Replication

(2010) P. Friebe et al.   JOURNAL OF VIROLOGY

An RNA Pseudoknot Is Required for Production of Yellow Fever Virus Subgenomic RNA by the Host Nuclease XRN1

(2010) P. A. G. C. Silva et al.   JOURNAL OF VIROLOGY

The Endoplasmic Reticulum Provides the Membrane Platform for Biogenesis of the Flavivirus Replication Complex

(2010) Leah K. Gillespie et al.   JOURNAL OF VIROLOGY

Influence of pr-M Cleavage on the Heterogeneity of Extracellular Dengue Virus Particles

(2010) J. Junjhon et al.   JOURNAL OF VIROLOGY

Molecular mechanisms involved in the early steps of flavivirus cell entry

(2010) Bärbel Kaufmann et al.   MICROBES AND INFECTION

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

A balance between circular and linear forms of the dengue virus genome is crucial for viral replication

(2010) S. M. Villordo et al.   RNA

Molecular mechanisms of flavivirus membrane fusion

(2009) Karin Stiasny et al.   AMINO ACIDS

Structure and functionality in flavivirus NS-proteins: Perspectives for drug design

(2009) Michela Bollati et al.   ANTIVIRAL RESEARCH

Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites

(2009) Sonja Welsch et al.   Cell Host & Microbe

La protein binds the predicted loop structures in the 3' non-coding region of Japanese encephalitis virus genome: role in virus replication

(2009) S. Vashist et al.   JOURNAL OF GENERAL VIROLOGY

Association of the pr Peptides with Dengue Virus at Acidic pH Blocks Membrane Fusion

(2009) I.-M. Yu et al.   JOURNAL OF VIROLOGY

NS1' of Flaviviruses in the Japanese Encephalitis Virus Serogroup Is a Product of Ribosomal Frameshifting and Plays a Role in Viral Neuroinvasiveness

(2009) E. B. Melian et al.   JOURNAL OF VIROLOGY

Crystal Structure of a Novel Conformational State of the Flavivirus NS3 Protein: Implications for Polyprotein Processing and Viral Replication

(2009) R. Assenberg et al.   JOURNAL OF VIROLOGY

3' cis-Acting Elements That Contribute to the Competence and Efficiency of Japanese Encephalitis Virus Genome Replication: Functional Importance of Sequence Duplications, Deletions, and Substitutions

(2009) S.-I. Yun et al.   JOURNAL OF VIROLOGY

Crystal Structure of Dengue Virus Type 1 Envelope Protein in the Postfusion Conformation and Its Implications for Membrane Fusion

(2009) V. Nayak et al.   JOURNAL OF VIROLOGY

Zika Virus Outbreak on Yap Island, Federated States of Micronesia

(2009) Mark R. Duffy et al.   NEW ENGLAND JOURNAL OF MEDICINE

A conserved predicted pseudoknot in the NS2A-encoding sequence of West Nile and Japanese encephalitis flaviviruses suggests NS1' may derive from ribosomal frameshifting

(2009) Andrew E Firth et al.   Virology Journal

Flavivirus methyltransferase: A novel antiviral target

(2008) Hongping Dong et al.   ANTIVIRAL RESEARCH

A Highly Structured, Nuclease-Resistant, Noncoding RNA Produced by Flaviviruses Is Required for Pathogenicity

(2008) Gorben P. Pijlman et al.   Cell Host & Microbe

Functional entry of dengue virus into Aedes albopictus mosquito cells is dependent on clathrin-mediated endocytosis

(2008) E. G. Acosta et al.   JOURNAL OF GENERAL VIROLOGY

Structural and Functional Studies of the Promoter Element for Dengue Virus RNA Replication

(2008) M. F. Lodeiro et al.   JOURNAL OF VIROLOGY

Yellow Fever Virus NS3 Plays an Essential Role in Virus Assembly Independent of Its Known Enzymatic Functions

(2008) C. G. Patkar et al.   JOURNAL OF VIROLOGY

Role of Nonstructural Protein NS2A in Flavivirus Assembly

(2008) J. Y. Leung et al.   JOURNAL OF VIROLOGY

Pathogenic flaviviruses

(2008) EA Gould et al.   LANCET

A complex RNA motif defined by three discontinuous 5-nucleotide-long strands is essential for Flavivirus RNA replication

(2008) B.-H. Song et al.   RNA

The Flavivirus Precursor Membrane-Envelope Protein Complex: Structure and Maturation

(2008) L. Li et al.   SCIENCE

Structure of the Immature Dengue Virus at Low pH Primes Proteolytic Maturation

(2008) I-M. Yu et al.   SCIENCE

The capsid-coding region hairpin element (cHP) is a critical determinant of dengue virus and West Nile virus RNA synthesis

(2008) Karen Clyde et al.   VIROLOGY

Terminal structures of West Nile virus genomic RNA and their interactions with viral NS5 protein

(2008) Hongping Dong et al.   VIROLOGY

West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions

(2008) Bo Zhang et al.   VIROLOGY

Endocytic pathway followed by dengue virus to infect the mosquito cell line C6/36 HT

(2008) Clemente Mosso et al.   VIROLOGY

Dissecting the Cell Entry Pathway of Dengue Virus by Single-Particle Tracking in Living Cells

(2008) Hilde M. van der Schaar et al.   PLoS Pathogens