Identification of Resveratrol, an Herbal Compound, as an Activator of the Calcium-Activated Chloride Channel, TMEM16A

Engineering a peptide inhibitor towards the KCNQ1/KCNE1 potassium channel (IKs)

(2015) Youtian Hu et al.   PEPTIDES

CLCA1 and TMEM16A: the link towards a potential cure for airway diseases

(2015) Tom J Brett   Expert Review of Respiratory Medicine

Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas

(2015) Laura Masuelli et al.   Oncotarget

Resveratrol Inhibits Glycine Receptor-Mediated Ion Currents

(2014) Byung-Hwan Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

TRPM4 inhibitor 9-phenanthrol activates endothelial cell intermediate conductance calcium-activated potassium channels in rat isolated mesenteric artery

(2014) C J Garland et al.   BRITISH JOURNAL OF PHARMACOLOGY

Abstract LB-205: The calcium activated chloride channel ANO1 promotes breast cancer progression by activating EGFR- and CAMK-signaling.

(2014) Adrian Britschgi et al.   CANCER RESEARCH

Lipid based nanoemulsifying resveratrol for improved physicochemical characteristics, in vitro cytotoxicity and in vivo antiangiogenic efficacy

(2014) Swati Pund et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

The TMEM16A chloride channel as an alternative therapeutic target in cystic fibrosis

(2014) Elvira Sondo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Immunomodulatory Effects of High-Protein Diet with Resveratrol Supplementation on Radiation-Induced Acute-Phase Inflammation in Rats

(2014) Kyoung-Ok Kim et al.   JOURNAL OF MEDICINAL FOOD

Resveratrol treatment as an adjunct to pharmacological management in type 2 diabetes mellitus-systematic review and meta-analysis

(2014) Heather A. Hausenblas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Chemistry: Chemical con artists foil drug discovery

(2014) Jonathan Baell et al.   NATURE

Inhibition of TMEM16A Expression Suppresses Growth and Invasion in Human Colorectal Cancer Cells

(2014) Yujie Sui et al.   PLoS One

Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention

(2014) D. Lissa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anoctamin 1 dysregulation alters bronchial epithelial repair in cystic fibrosis

(2013) Manon Ruffin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Enhanced antioxidant effect oftrans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin

(2013) Josè Ramon Moyano-Mendez et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases

(2013) Albino Carrizzo et al.   FOOD AND CHEMICAL TOXICOLOGY

Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice

(2013) Eun-A Ko et al.   GUT

Resveratrol Inhibits the Epithelial Sodium Channel via Phopshoinositides and AMP-Activated Protein Kinase in Kidney Collecting Duct Cells

(2013) Kelly M. Weixel et al.   PLoS One

TMEM16A/B Associated CaCC: Structural and Functional Insights

(2013) Chunli Pang et al.   PROTEIN AND PEPTIDE LETTERS

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

(2012) Hawon Cho et al.   NATURE NEUROSCIENCE

Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction

(2012) F. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroprotective and metabolic effects of resveratrol: Therapeutic implications for Huntington's disease and other neurodegenerative disorders

(2011) Giulio Maria Pasinetti et al.   EXPERIMENTAL NEUROLOGY

Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction

(2011) Wan Namkung et al.   FASEB JOURNAL

Neuroprotective properties of resveratrol in different neurodegenerative disorders

(2010) Diego Albani et al.   BIOFACTORS

Inhibition of Ca2+-activated Cl− channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea

(2010) Wan Namkung et al.   FASEB JOURNAL

Chloride Channels: Often Enigmatic, Rarely Predictable

(2009) Charity Duran et al.   Annual Review of Physiology

Bestrophin and TMEM16—Ca2+ activated Cl− channels with different functions

(2009) Karl Kunzelmann et al.   CELL CALCIUM

Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles

(2009) Sung Jin Hwang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Recurrent severe lower respiratory tract infections in a child with abnormal tracheal morphology

(2009) Serena Panigada et al.   PEDIATRIC PULMONOLOGY

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

Resveratrol Inhibits Electrical Activity and Insulin Release from Insulinoma Cells by Block of Voltage-Gated Ca2+ Channels and Swelling-Dependent Cl- Currents

(2008) Martin Jakab et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

TMEM16A confers receptor-activated calcium-dependent chloride conductance

(2008) Young Duk Yang et al.   NATURE

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE