One mutation, two distinct disease variants: unravelling the impact of transthyretin amyloid fibril composition

Multimodality Imaging of Cardiac Transthyretin Amyloidosis 16 Years After a Domino Liver Transplantation

(2016) M. Y. Bechiri et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Carpal tunnel syndrome: a common initial symptom of systemic wild-type ATTR (ATTRwt) amyloidosis

(2016) Michitaka Nakagawa et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

99mTc-DPD scintigraphy as a novel imaging modality for identification of skeletal muscle amyloid deposition in light-chain amyloidosis

(2016) David F. Hutt et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides

(2016) Elizabeth J. Ackermann et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Novel conformation-specific monoclonal antibodies against amyloidogenic forms of transthyretin

(2016) Jeffrey N. Higaki et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Nonbiopsy Diagnosis of Cardiac Transthyretin AmyloidosisCLINICAL PERSPECTIVE

(2016) Julian D. Gillmore et al.   CIRCULATION

99mTc-DPD-scintigraphy with intense uptake in fat tissue caused by AL-amyloidosis

(2016) M. Zoller et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Positron emission tomography (PET) utilizing Pittsburgh compound B (PIB) for detection of amyloid heart deposits in hereditary transthyretin amyloidosis (ATTR)

(2016) Björn Pilebro et al.   JOURNAL OF NUCLEAR CARDIOLOGY

99mTc-DPD uptake reflects amyloid fibril composition in hereditary transthyretin amyloidosis

(2016) Björn Pilebro et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity

(2016) Ricardo Sant'Anna et al.   Nature Communications

Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer

(2016) Irina Iakovleva et al.   PLoS One

Personalized medicine approach for optimizing the dose of tafamidis to potentially ameliorate wild-type transthyretin amyloidosis (cardiomyopathy)

(2015) Younhee Cho et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

(2015) J. Marcoux et al.   EMBO Molecular Medicine

Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component

(2015) Duncan B. Richards et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 2 open-label extention (OLE) study of patisiran, an investigational siRNA agent for familial amyloidotic polyneuropathy (FAP)

(2015) David Adams et al.   Orphanet Journal of Rare Diseases

Characterization of conformation-specific, human-derived monoclonal antibodies against TTR aggregates with potential for diagnostic and therapeutic use

(2015) Aubin Michalon et al.   Orphanet Journal of Rare Diseases

Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study

(2015) Ole B Suhr et al.   Orphanet Journal of Rare Diseases

Liver Transplantation for Hereditary Transthyretin Amyloidosis

(2015) Bo-Göran Ericzon et al.   TRANSPLANTATION

Repurposing Diflunisal for Familial Amyloid Polyneuropathy

(2015) John L. Berk et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Yield of Noncardiac Biopsy for the Diagnosis of Transthyretin Cardiac Amyloidosis

(2014) Nowell M. Fine et al.   AMERICAN JOURNAL OF CARDIOLOGY

Frequency of the transthyretin Val30Met mutation in the northern Swedish population

(2014) Malin Olsson et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Noninvasive detection of cardiac involvement in patients with hereditary transthyretin associated amyloidosis using cardiac magnetic resonance imaging: a prospective study

(2014) Jean-François Deux et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Imaging cardiac amyloidosis: a pilot study using 18F-florbetapir positron emission tomography

(2014) Sharmila Dorbala et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Efficacy of diflunisal on autonomic dysfunction of late-onset familial amyloid polyneuropathy (TTR Val30Met) in a Japanese endemic area

(2014) Ryoichi Takahashi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Amyloid deposits derived from transthyretin in the ligamentum flavum as related to lumbar spinal canal stenosis

(2014) Akihiro Yanagisawa et al.   MODERN PATHOLOGY

THAOS: Gastrointestinal manifestations of transthyretin amyloidosis - common complications of a rare disease

(2014) Jonas Wixner et al.   Orphanet Journal of Rare Diseases

Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis

(2014) P. P. Mangione et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transthyretin-derived amyloidosis: Probably a common cause of lumbar spinal stenosis

(2014) Per Westermark et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Native T1 Mapping in Transthyretin Amyloidosis

(2014) Marianna Fontana et al.   JACC-Cardiovascular Imaging

CMR-Based Differentiation of AL and ATTR Cardiac Amyloidosis

(2014) Jason N. Dungu et al.   JACC-Cardiovascular Imaging

Utility and limitations of 3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy in systemic amyloidosis

(2014) David F. Hutt et al.   European Heart Journal-Cardiovascular Imaging

Amyloid fibrils containing fragmented ATTR may be the standard fibril composition in ATTR amyloidosis

(2013) Elisabet Ihse et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Impact of antibodies against amyloidogenic transthyretin (ATTR) on phenotypes of patients with familial amyloidotic polyneuropathy (FAP) ATTR Valine30Methionine

(2013) Konen Obayashi et al.   CLINICA CHIMICA ACTA

Effect on disability and safety of Tafamidis in late onset of Met30 transthyretin familial amyloid polyneuropathy

(2013) P. Lozeron et al.   EUROPEAN JOURNAL OF NEUROLOGY

Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis

(2013) Teresa Coelho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transthyretin Aggregate-Specific Antibodies Recognize Cryptic Epitopes on Patient-Derived Amyloid Fibrils

(2013) Monichan Phay et al.   REJUVENATION RESEARCH

Effects of Tafamidis on Transthyretin Stabilization and Clinical Outcomes in Patients with Non-Val30Met Transthyretin Amyloidosis

(2013) Giampaolo Merlini et al.   Journal of Cardiovascular Translational Research

Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: a phase II study

(2012) Laura Obici et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Clinical development of an antisense therapy for the treatment of transthyretin-associated polyneuropathy

(2012) Elizabeth J. Ackermann et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Quantification of Myocardial Extracellular Volume Fraction in Systemic AL Amyloidosis

(2012) Sanjay M. Banypersad et al.   Circulation-Cardiovascular Imaging

THAOS – The Transthyretin Amyloidosis Outcomes Survey: initial report on clinical manifestations in patients with hereditary and wild-type transthyretin amyloidosis

(2012) Teresa Coelho et al.   CURRENT MEDICAL RESEARCH AND OPINION

In Vivo Visualization of Amyloid Deposits in the Heart with 11C-PIB and PET

(2012) G. Antoni et al.   JOURNAL OF NUCLEAR MEDICINE

Gastric emptying in hereditary transthyretin amyloidosis: the impact of autonomic neuropathy

(2012) J. Wixner et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Tafamidis for transthyretin familial amyloid polyneuropathy: A randomized, controlled trial

(2012) T. Coelho et al.   NEUROLOGY

Amyloid Fibril Composition as a Predictor of Development of Cardiomyopathy After Liver Transplantation for Hereditary Transthyretin Amyloidosis

(2012) Sandra Gustafsson et al.   TRANSPLANTATION

Development of cardiomyopathy after liver transplantation in Swedish hereditary transthyretin amyloidosis (ATTR) patients

(2011) Sadahisa Okamoto et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Diagnostic value of abdominal wall fat pad biopsy in senile systemic amyloidosis

(2011) Shu-ichi Ikeda et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Experimentally Derived Structural Constraints for Amyloid Fibrils of Wild-Type Transthyretin

(2011) David A. Bateman et al.   BIOPHYSICAL JOURNAL

Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis

(2011) J. E. Ward et al.   BLOOD

Familial amyloid polyneuropathy

(2011) Violaine Planté-Bordeneuve et al.   LANCET NEUROLOGY

Heart complications in familial transthyretin amyloidosis: impact of age and gender

(2010) Rolf Hörnsten et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Biochemical effect of liver transplantation in two Swedish patients with familial amyloidotic polyneuropathy (FAP-met30)

(2010) Gösta Holmgren et al.   CLINICAL GENETICS

Variation in amount of wild-type transthyretin in different fibril and tissue types in ATTR amyloidosis

(2010) Elisabet Ihse et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Progression of transthyretin amyloid neuropathy after liver transplantation

(2010) J. J. Liepnieks et al.   NEUROLOGY

Penetrance estimation of TTR familial amyloid polyneuropathy (type I) in Brazilian families

(2009) M. A. C. Saporta et al.   EUROPEAN JOURNAL OF NEUROLOGY

Liver transplantation for familial amyloidotic polyneuropathy: Impact on Swedish patients' survival

(2009) Sadahisa Okamoto et al.   LIVER TRANSPLANTATION

Heterogeneity of penetrance in familial amyloid polyneuropathy, ATTR Val30Met, in the Swedish population

(2008) Urban Hellman et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Amyloid fibril composition is related to the phenotype of hereditary transthyretin V30M amyloidosis

(2008) E Ihse et al.   JOURNAL OF PATHOLOGY