T Cell–Derived IL-10 Impairs Host Resistance toMycobacterium tuberculosisInfection

Type I IFN Inhibits Alternative Macrophage Activation duringMycobacterium tuberculosisInfection and Leads to Enhanced Protection in the Absence of IFN-γ Signaling

(2016) Lúcia Moreira-Teixeira et al.   JOURNAL OF IMMUNOLOGY

Interleukin 27R regulates CD4+T cell phenotype and impacts protective immunity duringMycobacterium tuberculosisinfection

(2015) Egidio Torrado et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-10 Promotes Mycobacterium tuberculosis Disease Progression in CBA/J Mice

(2014) G. L. Beamer et al.   JOURNAL OF IMMUNOLOGY

Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing inMycobacterium tuberculosis–Infected Macrophages

(2014) Finlay W. McNab et al.   JOURNAL OF IMMUNOLOGY

The Immune Response in Tuberculosis

(2013) Anne O'Garra et al.   Annual Review of Immunology

TPL-2-ERK1/2 Signaling Promotes Host Resistance against Intracellular Bacterial Infection by Negative Regulation of Type I IFN Production

(2013) F. W. McNab et al.   JOURNAL OF IMMUNOLOGY

IL-10 Inhibits Mature Fibrotic Granuloma Formation during Mycobacterium tuberculosis Infection

(2013) J. C. Cyktor et al.   JOURNAL OF IMMUNOLOGY

Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells

(2013) M Jeyanathan et al.   Mucosal Immunology

Clonal Expansions of CD8+ T Cells with IL-10 Secreting Capacity Occur during Chronic Mycobacterium tuberculosis Infection

(2013) Joshua C. Cyktor et al.   PLoS One

Blockade of IL-10 Signaling during Bacillus Calmette-Guerin Vaccination Enhances and Sustains Th1, Th17, and Innate Lymphoid IFN-  and IL-17 Responses and Increases Protection to Mycobacterium tuberculosis Infection

(2012) J. M. Pitt et al.   JOURNAL OF IMMUNOLOGY

Innate and Adaptive Interferons Suppress IL-1α and IL-1β Production by Distinct Pulmonary Myeloid Subsets during Mycobacterium tuberculosis Infection

(2011) Katrin D. Mayer-Barber et al.   IMMUNITY

IL-27 Promotes IL-10 Production by Effector Th1 CD4+ T Cells: A Critical Mechanism for Protection from Severe Immunopathology during Malaria Infection

(2011) A. P. Freitas do Rosario et al.   JOURNAL OF IMMUNOLOGY

Highly Activated Cytotoxic CD8 T Cells Express Protective IL-10 at the Peak of Coronavirus-Induced Encephalitis

(2011) K. Trandem et al.   JOURNAL OF IMMUNOLOGY

The role of IL-10 in immune regulation during M. tuberculosis infection

(2011) P S Redford et al.   Mucosal Immunology

IL-10 Blocks Phagosome Maturation inMycobacterium tuberculosis–Infected Human Macrophages

(2010) Seónadh O'Leary et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung

(2010) Paul S. Redford et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The adaptor molecule CARD9 is essential for tuberculosis control

(2010) Anca Dorhoi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cell-Mediated Immune Responses in Tuberculosis

(2009) Andrea M. Cooper   Annual Review of Immunology

Coactivation of Syk Kinase and MyD88 Adaptor Protein Pathways by Bacteria Promotes Regulatory Properties of Neutrophils

(2009) Xiaoming Zhang et al.   IMMUNITY

IL-27 Regulates IL-10 and IL-17 from CD4+ Cells in Nonhealing Leishmania major Infection

(2009) C. F. Anderson et al.   JOURNAL OF IMMUNOLOGY

Autocrine IL-10 Induces Hallmarks of Alternative Activation in Macrophages and Suppresses Antituberculosis Effector Mechanisms without Compromising T Cell Immunity

(2009) T. Schreiber et al.   JOURNAL OF IMMUNOLOGY

Tuberculosis Is Associated with a Down-Modulatory Lung Immune Response That Impairs Th1-Type Immunity

(2009) A. S. Almeida et al.   JOURNAL OF IMMUNOLOGY

Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10

(2009) Jie Sun et al.   NATURE MEDICINE

Lack of IL-10 alters inflammatory and immune responses during pulmonary Mycobacterium tuberculosis infection

(2009) David M. Higgins et al.   TUBERCULOSIS

IL-10 from CD4+CD25−Foxp3−CD127− Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection

(2008) Kevin N. Couper et al.   PLoS Pathogens