Interleukin 27R regulates CD4+T cell phenotype and impacts protective immunity duringMycobacterium tuberculosisinfection

The onset of adaptive immunity in the mouse model of tuberculosis and the factors that compromise its expression

(2015) Richard T. Robinson et al.   IMMUNOLOGICAL REVIEWS

ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis

(2015) Albanus O. Moguche et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The balance between protective and pathogenic immune responses in the TB-infected lung

(2015) Ian M Orme et al.   NATURE IMMUNOLOGY

Mycobacterium tuberculosis-Specific CD8+ T Cells Require Perforin to Kill Target Cells and Provide Protection In Vivo

(2014) J. S. Woodworth et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Control of Mycobacterium tuberculosis Infection by a Subset of Lung Parenchyma-Homing CD4 T Cells

(2014) S. Sakai et al.   JOURNAL OF IMMUNOLOGY

Protective CD4 T Cells Targeting Cryptic Epitopes of Mycobacterium tuberculosis Resist Infection-Driven Terminal Differentiation

(2014) J. S. Woodworth et al.   JOURNAL OF IMMUNOLOGY

Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2

(2014) K. Kai McKinstry et al.   Nature Communications

The immunopathogenesis of the HIV tuberculosis immune reconstitution inflammatory syndrome

(2013) Rachel P. J. Lai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Killer Cell Lectin-Like Receptor G1 Deficiency Significantly Enhances Survival after Mycobacterium tuberculosis Infection

(2013) Joshua C. Cyktor et al.   INFECTION AND IMMUNITY

CXCR5+ T helper cells mediate protective immunity against tuberculosis

(2013) Samantha R. Slight et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Direct Recognition of Infected Cells by CD4 T Cells Is Required for Control of Intracellular Mycobacterium tuberculosis In Vivo

(2013) S. Srivastava et al.   JOURNAL OF IMMUNOLOGY

A Novel Role for IL-27 in Mediating the Survival of Activated Mouse CD4 T Lymphocytes

(2013) G. Kim et al.   JOURNAL OF IMMUNOLOGY

IL-27 Receptor Signaling Regulates CD4+ T Cell Chemotactic Responses during Infection

(2013) E. Gwyer Findlay et al.   JOURNAL OF IMMUNOLOGY

Control of Chronic Mycobacterium tuberculosis Infection by CD4 KLRG1- IL-2-Secreting Central Memory Cells

(2013) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY

Role of the Interleukin 10 Family of Cytokines in Patients With Immune Reconstitution Inflammatory Syndrome Associated With HIV Infection and Tuberculosis

(2013) Rebecca Tadokera et al.   JOURNAL OF INFECTIOUS DISEASES

Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial

(2013) Michele D Tameris et al.   LANCET

Complications of Antiretroviral Therapy Initiation in Hospitalised Patients with HIV-Associated Tuberculosis

(2013) Helen van der Plas et al.   PLoS One

Differential and Site Specific Impact of B Cells in the Protective Immune Response to Mycobacterium tuberculosis in the Mouse

(2013) Egídio Torrado et al.   PLoS One

Detection of Tuberculosis in HIV-Infected and -Uninfected African Adults Using Whole Blood RNA Expression Signatures: A Case-Control Study

(2013) Myrsini Kaforou et al.   PLOS MEDICINE

IL-27 Receptor Signalling Restricts the Formation of Pathogenic, Terminally Differentiated Th1 Cells during Malaria Infection by Repressing IL-12 Dependent Signals

(2013) Ana Villegas-Mendez et al.   PLoS Pathogens

Prospects for Tuberculosis Elimination

(2012) Christopher Dye et al.   Annual Review of Public Health

Corticosteroid Therapy, Vitamin D Status, and Inflammatory Cytokine Profile in the HIV-Tuberculosis Immune Reconstitution Inflammatory Syndrome

(2012) Anali Conesa-Botella et al.   CLINICAL INFECTIOUS DISEASES

Nitric oxide inhibits the accumulation of CD4+CD44hiTbet+CD69loT cells in mycobacterial infection

(2012) John E. Pearl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology

(2012) Aisling O’Hara Hall et al.   IMMUNITY

Interleukin-27: Balancing Protective and Pathological Immunity

(2012) Christopher A. Hunter et al.   IMMUNITY

Cell Origins and Diagnostic Accuracy of Interleukin 27 in Pleural Effusions

(2012) Wei-Bing Yang et al.   PLoS One

Interaction between HIV and Mycobacterium tuberculosis

(2012) Christof Geldmacher et al.   Current Opinion in HIV and AIDS

IL-23 Is Required for Long-Term Control of Mycobacterium tuberculosis and B Cell Follicle Formation in the Infected Lung

(2011) Shabaana A. Khader et al.   JOURNAL OF IMMUNOLOGY

gp130 on macrophages/granulocytes modulates inflammation during experimental tuberculosis

(2010) Jan Sodenkamp et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome

(2010) R. Tadokera et al.   EUROPEAN RESPIRATORY JOURNAL

Essential Role for IL-27 Receptor Signaling in Prevention of Th1-Mediated Immunopathology during Malaria Infection

(2010) E. G. Findlay et al.   JOURNAL OF IMMUNOLOGY

CD4 T Cells Promote Rather than Control Tuberculosis in the Absence of PD-1-Mediated Inhibition

(2010) D. L. Barber et al.   JOURNAL OF IMMUNOLOGY

A role for IL-27p28 as an antagonist of gp130-mediated signaling

(2010) Jason S Stumhofer et al.   NATURE IMMUNOLOGY

Distinct functions of antigen-specific CD4 T cells during murine Mycobacterium tuberculosis infection

(2010) W. W. Reiley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis

(2010) E. Lazar-Molnar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-Mediated Immune Responses in Tuberculosis

(2009) Andrea M. Cooper   Annual Review of Immunology

The IL-27 p28 Subunit Binds Cytokine-Like Factor 1 to Form a Cytokine Regulating NK and T Cell Activities Requiring IL-6R for Signaling

(2009) S. Crabe et al.   JOURNAL OF IMMUNOLOGY

In a Murine Tuberculosis Model, the Absence of Homeostatic Chemokines Delays Granuloma Formation and Protective Immunity

(2009) S. A. Khader et al.   JOURNAL OF IMMUNOLOGY

IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells

(2009) C. Diveu et al.   JOURNAL OF IMMUNOLOGY

Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells

(2009) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY

ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes

(2008) W. W. Reiley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA