PPAR-α Activation Mediates Innate Host Defense through Induction of TFEB and Lipid Catabolism
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
PPAR-α Activation Mediates Innate Host Defense through Induction of TFEB and Lipid Catabolism
Authors
Keywords
-
Journal
JOURNAL OF IMMUNOLOGY
Volume 198, Issue 8, Pages 3283-3295
Publisher
The American Association of Immunologists
Online
2017-03-09
DOI
10.4049/jimmunol.1601920
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Control of lysosomal biogenesis and Notch-dependent tissue patterning by components of the TFEB-V-ATPase axis inDrosophila melanogaster
- (2016) Emiliana Tognon et al. Autophagy
- Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation
- (2016) Sunmin Park et al. Cell Host & Microbe
- Human Xenobiotic Nuclear Receptor PXR AugmentsMycobacterium tuberculosisSurvival
- (2016) Ella Bhagyaraj et al. JOURNAL OF IMMUNOLOGY
- Host-directed therapies for infectious diseases: current status, recent progress, and future prospects
- (2016) Alimuddin Zumla et al. LANCET INFECTIOUS DISEASES
- Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism
- (2016) Mireille Ouimet et al. NATURE IMMUNOLOGY
- NR1D1 amelioratesMycobacterium tuberculosisclearance through regulation of autophagy
- (2015) Vemika Chandra et al. Autophagy
- Treatment in vitro with PPARα and PPARγ ligands drives M1-to-M2 polarization of macrophages from T. cruzi-infected mice
- (2015) Federico Penas et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation
- (2015) Jae-Min Yuk et al. IMMUNITY
- Activation of Peroxisome Proliferator-activated Receptor α Induces Lysosomal Biogenesis in Brain Cells
- (2015) Arunava Ghosh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Engagement of the Aryl Hydrocarbon Receptor inMycobacterium tuberculosis–Infected Macrophages Has Pleiotropic Effects on Innate Immune Signaling
- (2015) Babak Memari et al. JOURNAL OF IMMUNOLOGY
- Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection
- (2015) Jacqueline M. Kimmey et al. NATURE
- Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
- (2015) S. Okada et al. SCIENCE
- Therapeutic Effects of PPARαon Neuronal Death and Microvascular Impairment
- (2015) Elizabeth P. Moran et al. PPAR Research
- The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy
- (2014) Chul-Su Yang et al. Autophagy
- Innate Host Defense Requires TFEB-Mediated Transcription of Cytoprotective and Antimicrobial Genes
- (2014) Orane Visvikis et al. IMMUNITY
- Nutrient-sensing nuclear receptors coordinate autophagy
- (2014) Jae Man Lee et al. NATURE
- Peroxisome proliferator-activated receptor α activation attenuates the inflammatory response to protect the liver from acute failure by promoting the autophagy pathway
- (2014) M Jiao et al. Cell Death & Disease
- Allele-Specific Induction of IL-1β Expression by C/EBPβ and PU.1 Contributes to Increased Tuberculosis Susceptibility
- (2014) Guoliang Zhang et al. PLoS Pathogens
- Integrated physiology and systems biology of PPARα
- (2014) Sander Kersten Molecular Metabolism
- Exploitation of host lipids by bacteria
- (2013) François Vromman et al. CURRENT OPINION IN MICROBIOLOGY
- TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
- (2013) Carmine Settembre et al. NATURE CELL BIOLOGY
- Host Cell Autophagy Activated by Antibiotics Is Required for Their Effective Antimycobacterial Drug Action
- (2012) Jwa-Jin Kim et al. Cell Host & Microbe
- Mycobacterium tuberculosis-Driven Targeted Recalibration of Macrophage Lipid Homeostasis Promotes the Foamy Phenotype
- (2012) Varshneya Singh et al. Cell Host & Microbe
- Failure To Recruit Anti-Inflammatory CD103+Dendritic Cells and a Diminished CD4+Foxp3+Regulatory T Cell Pool in Mice That Display Excessive Lung Inflammation and Increased Susceptibility to Mycobacterium tuberculosis
- (2012) Chaniya Leepiyasakulchai et al. INFECTION AND IMMUNITY
- Mycobacterium tuberculosis Modulates Macrophage Lipid-Sensing Nuclear Receptors PPAR and TR4 for Survival
- (2012) S. Mahajan et al. JOURNAL OF IMMUNOLOGY
- The nuclear receptor PPARs as important regulators of T-cell functions and autoimmune diseases
- (2012) Je-Min Choi et al. MOLECULES AND CELLS
- PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
- (2011) Tamas Varga et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Lack of IL-2 in PPAR-α-deficient mice triggers allergic contact dermatitis by affecting regulatory T cells
- (2011) Sandrine Dubrac et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
- (2011) Michela Palmieri et al. HUMAN MOLECULAR GENETICS
- Autophagy in immunity and inflammation
- (2011) Beth Levine et al. NATURE
- A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis
- (2011) Kari A Sweeney et al. NATURE MEDICINE
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages
- (2011) Jaiyanth Daniel et al. PLoS Pathogens
- Autophagy Negatively Regulates Keratinocyte Inflammatory Responses via Scaffolding Protein p62/SQSTM1
- (2010) H.-M. Lee et al. JOURNAL OF IMMUNOLOGY
- Dissection of Rab7 localization on Mycobacterium tuberculosis phagosome
- (2009) Shintaro Seto et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin
- (2009) Jae-Min Yuk et al. Cell Host & Microbe
- Mycobacterium bovis Bacillus Calmette-Guerin Infection Induces TLR2-Dependent Peroxisome Proliferator-Activated Receptor Expression and Activation: Functions in Inflammation, Lipid Metabolism, and Pathogenesis
- (2009) P. E. Almeida et al. JOURNAL OF IMMUNOLOGY
- Dominant‐Negative Tumor Necrosis Factor Protects fromMycobacterium bovisBacillus Calmette‐Guérin (BCG) and Endotoxin‐Induced Liver Injury without Compromising Host Immunity to BCG andMycobacterium tuberculosis
- (2009) Maria L. Olleros et al. JOURNAL OF INFECTIOUS DISEASES
- Autophagy genes in immunity
- (2009) Herbert W Virgin et al. NATURE IMMUNOLOGY
- A Gene Network Regulating Lysosomal Biogenesis and Function
- (2009) Marco Sardiello et al. SCIENCE
- Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence
- (2008) Pascale Peyron et al. PLoS Pathogens
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started