TIM-4 Identifies IFN-γ–Expressing Proinflammatory B Effector 1 Cells That Promote Tumor and Allograft Rejection

TIM-1 Signaling Is Required for Maintenance and Induction of Regulatory B Cells

(2015) M. Y. Yeung et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Pathogenic functions of B cells in autoimmune diseases: IFN-γ production joins the criminal gang

(2015) Simon Fillatreau   EUROPEAN JOURNAL OF IMMUNOLOGY

B cells expressing IFN-γ suppress Treg-cell differentiation and promote autoimmune experimental arthritis

(2015) Susan A. Olalekan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cytokine-producing B cells: a translational view on their roles in human and mouse autoimmune diseases

(2015) Andreia C. Lino et al.   IMMUNOLOGICAL REVIEWS

The expanding family of regulatory B cells

(2015) Claudia Mauri et al.   INTERNATIONAL IMMUNOLOGY

Tim-1 Is Essential for Induction and Maintenance of IL-10 in Regulatory B Cells and Their Regulation of Tissue Inflammation

(2015) Sheng Xiao et al.   JOURNAL OF IMMUNOLOGY

Regulatory B cells preferentially accumulate in tumor-draining lymph nodes and promote tumor growth

(2015) Sheila N. Ganti et al.   Scientific Reports

B10 cell regulation of health and disease

(2014) Kathleen M. Candando et al.   IMMUNOLOGICAL REVIEWS

B cells mediate chronic allograft rejection independently of antibody production

(2014) Qiang Zeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Suppression of Proteoglycan-Induced Arthritis by Anti-CD20 B Cell Depletion Therapy Is Mediated by Reduction in Autoantibodies and CD4+ T Cell Reactivity

(2014) K. Hamel et al.   JOURNAL OF IMMUNOLOGY

Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial

(2014) Ludwig Kappos et al.   LANCET NEUROLOGY

The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis

(2014) Ronald S. Flannagan et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8+ T cells directly within the tumor microenvironment

(2014) Stefani Spranger et al.   Journal for ImmunoTherapy of Cancer

Identification of IFN-γ-producing innate B cells

(2013) Yan Bao et al.   CELL RESEARCH

Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma

(2013) J.-Y. Shi et al.   CLINICAL CANCER RESEARCH

The effect of B-cell depletion therapy on serological evidence of B-cell and plasmablast activation in patients with rheumatoid arthritis over multiple cycles of rituximab treatment

(2013) G. Cambridge et al.   JOURNAL OF AUTOIMMUNITY

Interruption of Dendritic Cell-Mediated TIM-4 Signaling Induces Regulatory T Cells and Promotes Skin Allograft Survival

(2013) M. Y. Yeung et al.   JOURNAL OF IMMUNOLOGY

B regulatory cells in cancer

(2012) Frances Balkwill et al.   TRENDS IN IMMUNOLOGY

Tumor-infiltrating B cells and T cells

(2012) Julie S. Nielsen et al.   OncoImmunology

Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice

(2011) Qing Ding et al.   JOURNAL OF CLINICAL INVESTIGATION

Two-Step Engulfment of Apoptotic Cells

(2011) S. Toda et al.   MOLECULAR AND CELLULAR BIOLOGY

B regulatory cells and the tumor-promoting actions of TNF-  during squamous carcinogenesis

(2011) T. Schioppa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B Cells Help Alloreactive T Cells Differentiate Into Memory T Cells

(2010) Y.-H. Ng et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Am"B"valent: anti-CD20 antibodies unravel the dual role of B cells in immunopathogenesis

(2010) O. Thaunat et al.   BLOOD

TLR and B Cell Receptor Signals to B Cells Differentially Program Primary and Memory Th1 Responses to Salmonella enterica

(2010) T. A. Barr et al.   JOURNAL OF IMMUNOLOGY

B Cells Are Required for Optimal CD4+ and CD8+ T Cell Tumor Immunity: Therapeutic B Cell Depletion Enhances B16 Melanoma Growth in Mice

(2010) D. J. DiLillo et al.   JOURNAL OF IMMUNOLOGY

CD20+ B Cells: The Other Tumor-Infiltrating Lymphocytes

(2010) B. H. Nelson   JOURNAL OF IMMUNOLOGY

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

(2010) R. Rodriguez-Manzanet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

(2010) M. A. Curran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Phosphatidylserine Receptor TIM-4 Does Not Mediate Direct Signaling

(2009) Daeho Park et al.   CURRENT BIOLOGY

B-Cell–Depleting Induction Therapy and Acute Cellular Rejection

(2009) Menna R. Clatworthy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anti-CD20 therapy in patients with rheumatoid arthritis: Predictors of response and B cell subset regeneration after repeated treatment

(2008) Petra Roll et al.   ARTHRITIS AND RHEUMATISM

A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

(2008) Koichi Yanaba et al.   IMMUNITY

Regulatory B cells as inhibitors of immune responses and inflammation

(2008) Jean-David Bouaziz et al.   IMMUNOLOGICAL REVIEWS

Bimodal regulation of T cell-mediated immune responses by TIM-4

(2008) M. Mizui et al.   INTERNATIONAL IMMUNOLOGY

Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression

(2008) Takashi Matsushita et al.   JOURNAL OF CLINICAL INVESTIGATION