TLR8: the forgotten relative revindicated

TLR7 Is Involved in Sequence-Specific Sensing of Single-Stranded RNAs in Human Macrophages

(2014) M. P. Gantier et al.   JOURNAL OF IMMUNOLOGY

Identification of RNA Sequence Motifs Stimulating Sequence-Specific TLR8-Dependent Immune Responses

(2014) A. Forsbach et al.   JOURNAL OF IMMUNOLOGY

R-848 triggers the expression of TLR7/8 and suppresses HIV replication in monocytes

(2012) Hua Nian et al.   BMC INFECTIOUS DISEASES

New developments in Toll-like receptor targeted therapeutics

(2012) Dympna J Connolly et al.   CURRENT OPINION IN PHARMACOLOGY

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

(2012) Tengchuan Jin et al.   IMMUNITY

The 2′-O-methylation status of a single guanosine controls transfer RNA–mediated Toll-like receptor 7 activation or inhibition

(2012) Stefanie Jöckel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Le récepteur Toll-like8

(2012) Lena Alexopoulou et al.   M S-MEDECINE SCIENCES

The TLR7/8 ligand resiquimod targets monocyte-derived dendritic cell differentiation via TLR8 and augments functional dendritic cell generation

(2011) Holger Hackstein et al.   CELLULAR IMMUNOLOGY

VTX-2337 Is a Novel TLR8 Agonist That Activates NK Cells and Augments ADCC

(2011) H. Lu et al.   CLINICAL CANCER RESEARCH

CS17-4. Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes

(2011) Jorge L. Cervantes et al.   CYTOKINE

VTX-1463, a novel TLR8 agonist for the treatment of allergic rhinitis

(2011) Friedrich Horak   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

(2011) Leif E. Sander et al.   NATURE

UNC93B1 Physically Associates with Human TLR8 and Regulates TLR8-Mediated Signaling

(2011) Hiroki Itoh et al.   PLoS One

Phagosomal signaling byBorrelia burgdorferiin human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β

(2011) Jorge L. Cervantes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exposure to HIV-1-encoded Toll-like receptor 8 ligands enhances monocyte response to microbial encoded Toll-like receptor 2/4 ligands

(2010) Marianne W Mureith et al.   AIDS

Genetic modulation of TLR8 response following bacterial phagocytosis

(2010) Michael P. Gantier et al.   HUMAN MUTATION

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

Association between toll-like receptor expression and human papillomavirus type 16 persistence

(2010) Ibrahim I. Daud et al.   INTERNATIONAL JOURNAL OF CANCER

HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells

(2010) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Expression of Toll-like receptors 7, 8, and 9 in primary Sjögren's syndrome

(2010) Lingyan Zheng et al.   ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS

Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA

(2010) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC?

(2010) S. Bauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity

(2010) Jun Du et al.   VACCINE

Bacterial RNA is recognized by different sets of immunoreceptors

(2009) Florian Eberle et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells

(2009) S. M. Makela et al.   JOURNAL OF LEUKOCYTE BIOLOGY

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells

(2009) Giuseppe Mancuso et al.   NATURE IMMUNOLOGY

Intrinsic Cellular Defenses against Virus Infection by Antiviral Type I Interferon

(2009) Kyung-Hyun Boo et al.   YONSEI MEDICAL JOURNAL

Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β

(2009) Juan C. Salazar et al.   PLoS Pathogens

A Functional Toll‐Like Receptor 8 Variant Is Associated with HIV Disease Restriction

(2008) D.‐Y. Oh et al.   JOURNAL OF INFECTIOUS DISEASES

Porcine TLR8 and TLR7 are both activated by a selective TLR7 ligand, imiquimod

(2008) Jianzhong Zhu et al.   MOLECULAR IMMUNOLOGY

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

(2008) You-Me Kim et al.   NATURE

Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis

(2008) Sonia Davila et al.   PLoS Genetics

Toll-like receptors and autoimmunity

(2007) Julia Hurst et al.   AUTOIMMUNITY REVIEWS

The covalent modification and regulation of TLR8 in HEK-293 cells stimulated with imidazoquinoline agonists

(2007) Raj Rajagopal et al.   BIOCHEMICAL JOURNAL