Deep Immune Profiling of an Arginine-Enriched Nutritional Intervention in Patients Undergoing Surgery

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment

(2016) S. Kordasti et al.   BLOOD

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

(2016) Roger Geiger et al.   CELL

Effects of Immunonutrition for Cystectomy on Immune Response and Infection Rates: A Pilot Randomized Controlled Clinical Trial

(2016) Jill M. Hamilton-Reeves et al.   EUROPEAN UROLOGY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

(2016) Bernadette Carroll et al.   eLife

Patient-specific Immune States before Surgery Are Strong Correlates of Surgical Recovery

(2015) Gabriela K. Fragiadakis et al.   ANESTHESIOLOGY

Regulation of Tumor Metastasis by Myeloid-Derived Suppressor Cells

(2015) Thomas Condamine et al.   Annual Review of Medicine

Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

(2015) Jacob H. Levine et al.   CELL

Revisiting the crystal ball - high content single cells analysis as predictor of recovery

(2015) Attila Tárnok   CYTOMETRY PART A

Implementing Mass Cytometry at the Bedside to Study the Immunological Basis of Human Diseases: Distinctive Immune Features in Patients with a History of Term or Preterm Birth

(2015) Brice Gaudillière et al.   CYTOMETRY PART A

Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus

(2015) William E. O'Gorman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected

(2015) Douglas Marvel et al.   JOURNAL OF CLINICAL INVESTIGATION

Measure for measure

(2015) Jim Kling   NATURE

Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm

(2015) Eli R Zunder et al.   Nature Protocols

Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation

(2015) Dorota Klysz et al.   Science Signaling

Intersection of mTOR and STAT signaling in immunity

(2015) Diana Saleiro et al.   TRENDS IN IMMUNOLOGY

Fatty acid metabolism in the regulation of T cell function

(2015) Matthias Lochner et al.   TRENDS IN IMMUNOLOGY

Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy

(2015) Nitya Nair et al.   ARTHRITIS RESEARCH & THERAPY

Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation

(2015) Dorota Klysz et al.   Science Signaling

mTOR Links Environmental Signals to T Cell Fate Decisions

(2015) Nicole M. Chapman et al.   Frontiers in Immunology

L-Arginine Depletion Blunts Antitumor T-cell Responses by Inducing Myeloid-Derived Suppressor Cells

(2014) M. Fletcher et al.   CANCER RESEARCH

Transient partial permeabilization with saponin enables cellular barcoding prior to surface marker staining

(2014) Gregory K. Behbehani et al.   CYTOMETRY PART A

Clinical recovery from surgery correlates with single-cell immune signatures

(2014) B. Gaudilliere et al.   Science Translational Medicine

The Central Role of Arginine Catabolism in T-Cell Dysfunction and Increased Susceptibility to Infection After Physical Injury

(2013) Xinmei Zhu et al.   ANNALS OF SURGERY

Normalization of mass cytometry data with bead standards

(2013) Rachel Finck et al.   CYTOMETRY PART A

Critical assessment of automated flow cytometry data analysis techniques

(2013) Nima Aghaeepour et al.   NATURE METHODS

Myeloid-Derived Suppressor Cells in the Development of Lung Cancer

(2013) M. L. Ortiz et al.   Cancer Immunology Research

Early immunologic correlates of HIV protection can be identified from computational analysis of complex multivariate T-cell flow cytometry assays*

(2012) Nima Aghaeepour et al.   BIOINFORMATICS

Myeloid-derived suppressor cells control microbial sepsis

(2012) Marc Derive et al.   INTENSIVE CARE MEDICINE

Alarmins: awaiting a clinical response

(2012) James K. Chan et al.   JOURNAL OF CLINICAL INVESTIGATION

Ly6C+Ly6G−Myeloid-derived suppressor cells play a critical role in the resolution of acute inflammation and the subsequent tissue repair process after spinal cord injury

(2012) Hirokazu Saiwai et al.   JOURNAL OF NEUROCHEMISTRY

A Critical Role for STAT3 Transcription Factor Signaling in the Development and Maintenance of Human T Cell Memory

(2011) Andrea M. Siegel et al.   IMMUNITY

An Interleukin-21- Interleukin-10-STAT3 Pathway Is Critical for Functional Maturation of Memory CD8+ T Cells

(2011) Weiguo Cui et al.   IMMUNITY

A genomic storm in critically injured humans

(2011) Wenzhong Xiao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Systemic Arginine Depletion After a Murine Model of Surgery or Trauma

(2011) John P. Pribis et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Immunosupression and Infection After Major Surgery: A Nutritional Deficiency

(2010) Xinmei Zhu et al.   CRITICAL CARE CLINICS

Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function

(2010) Leif E. Sander et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Electronic properties of neuroleptics: ionization energies of benzodiazepines

(2010) Salvatore Millefiori et al.   JOURNAL OF MOLECULAR MODELING

TPL-2-Mediated Activation of MAPK Downstream of TLR4 Signaling Is Coupled to Arginine Availability

(2010) V. Mieulet et al.   Science Signaling

Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function

(2010) Thomas Condamine et al.   TRENDS IN IMMUNOLOGY

The Clavien-Dindo Classification of Surgical Complications

(2009) Pierre A. Clavien et al.   ANNALS OF SURGERY

Regulatory Myeloid Suppressor Cells in Health and Disease

(2009) S. Nagaraj et al.   CANCER RESEARCH

The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment

(2009) Greg M. Delgoffe et al.   IMMUNITY