Decidual T Cells Exhibit a Highly Differentiated Phenotype and Demonstrate Potential Fetal Specificity and a Strong Transcriptional Response to IFN

Programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) regulate CD4+T cells to induce Type 2 helper T cell (Th2) bias at the maternal–fetal interface

(2016) SongCun Wang et al.   HUMAN REPRODUCTION

Unsupervised Placental Gene Expression Profiling Identifies Clinically Relevant Subclasses of Human PreeclampsiaNovelty and Significance

(2016) Katherine Leavey et al.   HYPERTENSION

Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling

(2016) Miguel Pinilla-Vera et al.   PLoS One

Progesterone promotes maternal-fetal tolerance by reducing human maternal T-cell polyfunctionality and inducing a specific cytokine profile

(2015) David Lissauer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Novel role for galectin-1 in T-cells under physiological and pathological conditions

(2015) Magdolna Deák et al.   IMMUNOBIOLOGY

Decidual natural killer cells regulate vessel stability: implications for impaired spiral artery remodelling

(2015) Rupsha Fraser et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Chloride intracellular channel 1 (CLIC1) is activated and functions as an oncogene in pancreatic cancer

(2015) Jianhua Lu et al.   MEDICAL ONCOLOGY

Chloride intracellular channel 1 regulates migration and invasion in gastric cancer by triggering the ROS-mediated p38 MAPK signaling pathway

(2015) WEI ZHAO et al.   Molecular Medicine Reports

Links between recognition and degradation of cytoplasmic viral RNA in innate immune response

(2015) Hiroyuki Oshiumi et al.   REVIEWS IN MEDICAL VIROLOGY

PD-1 and Tim-3 pathways are associated with regulatory CD8+ T-cell function in decidua and maintenance of normal pregnancy

(2015) S-C Wang et al.   Cell Death & Disease

Interferon-α and Angiogenic Dysregulation in Pregnant Lupus Patients Who Develop Preeclampsia

(2015) Danieli Andrade et al.   Arthritis & Rheumatology

Chloride Intracellular Channel 1 Regulates Prostate Cancer Cell Proliferation and Migration Through the MAPK/ERK Pathway

(2014) Yudong Tian et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Galectin-9-CD44 Interaction Enhances Stability and Function of Adaptive Regulatory T Cells

(2014) Chuan Wu et al.   IMMUNITY

Uterine NK cells: active regulators at the maternal-fetal interface

(2014) Ashley Moffett et al.   JOURNAL OF CLINICAL INVESTIGATION

Evidence for a Selective Migration of Fetus-Specific CD4+CD25bright Regulatory T Cells from the Peripheral Blood to the Decidua in Human Pregnancy

(2014) T. Tilburgs et al.   JOURNAL OF IMMUNOLOGY

Peripheral Blood TIM-3 Positive NK and CD8+ T Cells throughout Pregnancy: TIM-3/Galectin-9 Interaction and Its Possible Role during Pregnancy

(2014) Matyas Meggyes et al.   PLoS One

Genome-wide miRNA profiling of villus and decidua of recurrent spontaneous abortion patients

(2014) Fulu Dong et al.   REPRODUCTION

The immunological basis of villitis of unknown etiology – Review

(2013) J.A. Tamblyn et al.   PLACENTA

Foxp3 Exploits a Pre-Existent Enhancer Landscape for Regulatory T Cell Lineage Specification

(2012) Robert M. Samstein et al.   CELL

Immune cell activation by trophoblast-derived microvesicles is mediated by syncytin 1

(2012) Beth S. Holder et al.   IMMUNOLOGY

Fetal-Specific CD8+ Cytotoxic T Cell Responses Develop during Normal Human Pregnancy and Exhibit Broad Functional Capacity

(2012) D. Lissauer et al.   JOURNAL OF IMMUNOLOGY

TIM-3 Regulates Innate Immune Cells To Induce Fetomaternal Tolerance

(2012) L. Chabtini et al.   JOURNAL OF IMMUNOLOGY

The Th1:Th2 Dichotomy of Pregnancy and Preterm Labour

(2012) Lynne Sykes et al.   MEDIATORS OF INFLAMMATION

Pregnancy imprints regulatory memory that sustains anergy to fetal antigen

(2012) Jared H. Rowe et al.   NATURE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Placental CLIC3 is increased in fetal growth restriction and pre-eclampsia affected human pregnancies

(2012) P. Murthi et al.   PLACENTA

The function and evolution of the restriction factor viperin in primates was not driven by lentiviruses

(2012) Efrem S Lim et al.   Retrovirology

Interaction between uterine natural killer cells and extravillous trophoblast cells: effect on cytokine and angiogenic growth factor production

(2011) Gendie E. Lash et al.   HUMAN REPRODUCTION

HLA-C as a mediator of natural killer and T-cell activation: spectator or key player?

(2011) Marie-Eve Blais et al.   IMMUNOLOGY

Th1/Th2/Th17 and Regulatory T-Cell Paradigm in Pregnancy

(2010) Shigeru Saito et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Chloride intracellular channel 1 (CLIC1): Sensor and effector during oxidative stress

(2010) Stefania Averaimo et al.   FEBS LETTERS

Human Decidual Tissue Contains Differentiated CD8+ Effector-Memory T Cells with Unique Properties

(2010) T. Tilburgs et al.   JOURNAL OF IMMUNOLOGY

Regulation of Hypoxia Inducible Factors (HIF) in Hypoxia and Normoxia During Placental Development

(2010) J. Patel et al.   PLACENTA

Naturally acquired tolerance and sensitization to minor histocompatibility antigens in healthy family members

(2009) A. G. S. van Halteren et al.   BLOOD

Expression of Th2-skewed pathology mediators in monocyte-derived type 2 of dendritic cells (DC2)

(2009) Mitsumi Hata et al.   IMMUNOLOGY LETTERS

Dendritic cell entrapment within the pregnant uterus inhibits immune surveillance of the maternal/fetal interface in mice

(2009) Mary K. Collins et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Chorionic Gonadotropin Attracts Regulatory T Cells into the Fetal-Maternal Interface during Early Human Pregnancy

(2009) A. Schumacher et al.   JOURNAL OF IMMUNOLOGY

Maternal PD-1 regulates accumulation of fetal antigen-specific CD8+ T cells in pregnancy

(2009) Elizabeth S. Taglauer et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Fetal–maternal HLA-C mismatch is associated with decidual T cell activation and induction of functional T regulatory cells

(2009) Tamara Tilburgs et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Decidual leucocyte populations in early to late gestation normal human pregnancy

(2009) P.J. Williams et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10

(2009) Juan M Ilarregui et al.   NATURE IMMUNOLOGY