Programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) regulate CD4+T cells to induce Type 2 helper T cell (Th2) bias at the maternal–fetal interface

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury

(2015) Yuanxing Liu et al.   JOURNAL OF HEPATOLOGY

Embryonic Trophoblasts Induce Decidual Regulatory T Cell Differentiation and Maternal-Fetal Tolerance through Thymic Stromal Lymphopoietin Instructing Dendritic Cells

(2014) M.-R. Du et al.   JOURNAL OF IMMUNOLOGY

Adoptive Transfer of Treg Cells Counters Adverse Effects of Toxoplasma gondii Infection on Pregnancy

(2014) Y. Liu et al.   JOURNAL OF INFECTIOUS DISEASES

Impaired selectin-dependent leukocyte recruitment induces T-cell exhaustion and prevents chronic allograft vasculopathy and rejection

(2014) B. Sarraj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Survival of Memory CD8 T Cells That Is Mediated by IL-15 Correlates with Sustained Protection Against Malaria

(2013) S. Zarling et al.   JOURNAL OF IMMUNOLOGY

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells

(2012) R. G. Veenstra et al.   BLOOD

Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma

(2012) Hang Li et al.   HEPATOLOGY

Allograft rejection is restrained by short-lived TIM-3+PD-1+Foxp3+ Tregs

(2012) Shipra Gupta et al.   JOURNAL OF CLINICAL INVESTIGATION

TIM-3 Regulates Innate Immune Cells To Induce Fetomaternal Tolerance

(2012) L. Chabtini et al.   JOURNAL OF IMMUNOLOGY

Tim-3-Expressing CD4+ and CD8+ T Cells in Human Tuberculosis (TB) Exhibit Polarized Effector Memory Phenotypes and Stronger Anti-TB Effector Functions

(2012) Yueqin Qiu et al.   PLoS Pathogens

The Link between the PDL1 Costimulatory Pathway and Th17 in Fetomaternal Tolerance

(2011) F. D'Addio et al.   JOURNAL OF IMMUNOLOGY

Reduced Tim-3 Expression on Human T-lymphotropic Virus Type I (HTLV-I) Tax-specific Cytotoxic T Lymphocytes in HTLV-I Infection

(2011) Nashwa H. Abdelbary et al.   JOURNAL OF INFECTIOUS DISEASES

HIV-specific CD4 T cells and immune control of viral replication

(2011) Filippos Porichis et al.   Current Opinion in HIV and AIDS

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Thymic stromal lymphopoietin from trophoblasts induces dendritic cell-mediated regulatory TH2 bias in the decidua during early gestation in humans

(2010) P.-F. Guo et al.   BLOOD

Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

(2010) Rachel H. McMahan et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

(2010) Kaori Sakuishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spontaneous Pregnancy Loss Mediated by Abnormal Maternal Inflammation in Rats Is Linked to Deficient Uteroplacental Perfusion

(2010) S. J. Renaud et al.   JOURNAL OF IMMUNOLOGY

TLR9 Activation Coupled to IL-10 Deficiency Induces Adverse Pregnancy Outcomes

(2009) J. E. Thaxton et al.   JOURNAL OF IMMUNOLOGY