Protective role of CX3CR1 signalling in resident cells of the central nervous system during experimental herpes simplex virus encephalitis

Bone marrow-derived macrophages and the CNS: An update on the use of experimental chimeric mouse models and bone marrow transplantation in neurological disorders

(2016) Antoine Larochelle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fractalkine Receptor Deficiency Is Associated with Early Protection but Late Worsening of Outcome following Brain Trauma in Mice

(2016) Elisa R. Zanier et al.   JOURNAL OF NEUROTRAUMA

Sub-acute systemic erythropoietin administration reduces ischemic brain injury in an age-dependent manner

(2016) Peter Thériault et al.   Oncotarget

Fractalkine in the nervous system: neuroprotective or neurotoxic molecule?

(2015) Clotilde Lauro et al.   Annals of the New York Academy of Sciences

Disruption of Fractalkine Signaling Leads to Microglial Activation and Neuronal Damage in the Diabetic Retina

(2015) Sandra M. Cardona et al.   ASN Neuro

CX3CL1/CX3CR1-Mediated Microglia Activation Plays a Detrimental Role in Ischemic Mice Brain via p38MAPK/PKC Pathway

(2015) Yong Liu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CX3CR1 Disruption Differentially Influences Dopaminergic Neuron Degeneration in Parkinsonian Mice Depending on the Neurotoxin and Route of Administration

(2015) Fabrine Sales Massafera Tristão et al.   NEUROTOXICITY RESEARCH

Microglia in Health and Disease

(2015) Richard M. Ransohoff et al.   Cold Spring Harbor Perspectives in Biology

Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis

(2015) Xi Feng et al.   Oncotarget

Infiltration Pattern of Blood Monocytes into the Central Nervous System during Experimental Herpes Simplex Virus Encephalitis

(2015) Rafik Menasria et al.   PLoS One

Microglial Cx3cr1 knockout reduces prion disease incubation time in mice

(2014) Julia Grizenkova et al.   BMC NEUROSCIENCE

Patrolling monocytes play a critical role in CX3CR1-mediated neuroprotection during excitotoxicity

(2014) Marc-André Bellavance et al.   Brain Structure & Function

The plasticity of inflammatory monocyte responses to the inflamed central nervous system

(2014) Thomas Myles Ashhurst et al.   CELLULAR IMMUNOLOGY

What is microglia neurotoxicity (Not)?

(2014) Knut Biber et al.   GLIA

Microglia-induced IL-6 protects against neuronal loss following HSV-1 infection of neural progenitor cells

(2014) Ana J. Chucair-Elliott et al.   GLIA

The Impact of Ly6Clow Monocytes after Cerebral Hypoxia-Ischemia in Adult Mice

(2014) Jean-Philippe Michaud et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Prolonged Microglial Cell Activation and Lymphocyte Infiltration following Experimental Herpes Encephalitis

(2014) C. P. Marques et al.   JOURNAL OF IMMUNOLOGY

Dysregulation of CXCR3 Signaling due to CXCL10 Deficiency Impairs the Antiviral Response to Herpes Simplex Virus 1 Infection

(2014) T. R. Wuest et al.   JOURNAL OF IMMUNOLOGY

CX3CR1 deficiency suppresses activation and neurotoxicity of microglia/macrophage in experimental ischemic stroke

(2014) Zhiwei Tang et al.   Journal of Neuroinflammation

Modulating neurotoxicity through CX3CL1/CX3CR1 signaling

(2014) Cristina Limatola et al.   Frontiers in Cellular Neuroscience

Fractalkine regulation of microglial physiology and consequences on the brain and behavior

(2014) Rosa Chiara Paolicelli et al.   Frontiers in Cellular Neuroscience

Update on Herpes Virus Infections of the Nervous System

(2013) Israel Steiner et al.   Current Neurology and Neuroscience Reports

CX3CR1 deficiency induces an early protective inflammatory environment in ischemic mice

(2013) Stefano Fumagalli et al.   GLIA

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

Microglia and a Functional Type I IFN Pathway Are Required To Counter HSV-1-Driven Brain Lateral Ventricle Enlargement and Encephalitis

(2013) C. D. Conrady et al.   JOURNAL OF IMMUNOLOGY

Regulation of Adaptive Immunity by the Fractalkine Receptor during Autoimmune Inflammation

(2013) J. A. Garcia et al.   JOURNAL OF IMMUNOLOGY

Immunological control of herpes simplex virus infections

(2013) Kevin P. Egan et al.   JOURNAL OF NEUROVIROLOGY

The brain’s best friend: microglial neurotoxicity revisited

(2013) Sabine Hellwig et al.   Frontiers in Cellular Neuroscience

Real-Time In Vivo Imaging Reveals the Ability of Monocytes to Clear Vascular Amyloid Beta

(2013) Jean-Philippe Michaud et al.   Cell Reports

Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage

(2013) G. K. Sheridan et al.   Open Biology

Impact of deficiency in CCR2 and CX3CR1 receptors on monocytes trafficking in herpes simplex virus encephalitis

(2012) N. Boivin et al.   JOURNAL OF GENERAL VIROLOGY

Inflammatory monocytes and the pathogenesis of viral encephalitis

(2012) Rachael L Terry et al.   Journal of Neuroinflammation

Hippocampal protection in mice with an attenuated inflammatory monocyte response to acute CNS picornavirus infection

(2012) Charles L. Howe et al.   Scientific Reports

In vivo structure/function and expression analysis of the CX3C chemokine fractalkine

(2011) K.-W. Kim et al.   BLOOD

Effects of Myeloablation, Peripheral Chimerism, and Whole-Body Irradiation on the Entry of Bone Marrow-Derived Cells into the Brain

(2011) Antoine Lampron et al.   CELL TRANSPLANTATION

CX3CR1 Protein Signaling Modulates Microglial Activation and Protects against Plaque-independent Cognitive Deficits in a Mouse Model of Alzheimer Disease

(2011) Seo-Hyun Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia

(2011) Shuxian Hu et al.   Journal of Neuroinflammation

Deficient CX3CR1 Signaling Promotes Recovery after Mouse Spinal Cord Injury by Limiting the Recruitment and Activation of Ly6Clo/iNOS+ Macrophages

(2011) D. J. Donnelly et al.   JOURNAL OF NEUROSCIENCE

CX3CL1 Is Neuroprotective in Permanent Focal Cerebral Ischemia in Rodents

(2011) R. Cipriani et al.   JOURNAL OF NEUROSCIENCE

CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity

(2011) J. T. Rogers et al.   JOURNAL OF NEUROSCIENCE

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

(2011) Marco Prinz et al.   NATURE NEUROSCIENCE

CX3CR1 Deficiency Alters Microglial Activation and Reduces Beta-Amyloid Deposition in Two Alzheimer's Disease Mouse Models

(2010) Sungho Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Tickets to the brain: Role of CCR2 and CX3CR1 in myeloid cell entry in the CNS

(2010) Marco Prinz et al.   JOURNAL OF NEUROIMMUNOLOGY

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

(2010) Martin Fuhrmann et al.   NATURE NEUROSCIENCE

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Redundancy in the immune system restricts the spread of HSV-1 in the central nervous system (CNS) of C57BL/6 mice

(2010) Lorne F. Kastrukoff et al.   VIROLOGY

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

(2009) Alexander Mildner et al.   BRAIN

Herpes simplex type I (HSV-1) infection of the nervous system: Is an immune response a good thing?

(2009) Christopher D. Conrady et al.   JOURNAL OF NEUROIMMUNOLOGY

The role of chemokines during herpes simplex virus-1 infection

(2008) Todd et al.   Frontiers in Bioscience-Landmark

Ly6c+“inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis

(2008) Daniel R. Getts et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Immune Response to Herpes Simplex Virus Type 1 Infection in Susceptible Mice Is a Major Cause of Central Nervous System Pathology Resulting in Fatal Encephalitis

(2008) P. Lundberg et al.   JOURNAL OF VIROLOGY

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

(2008) Jiyun V. Kim et al.   NATURE

Traffic of leukocytes in the central nervous system is associated with chemokine up-regulation in a severe model of herpes simplex encephalitis: An intravital microscopy study

(2008) Márcia Carvalho Vilela et al.   NEUROSCIENCE LETTERS