VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation

NRP1 function and targeting in neurovascular development and eye disease

(2016) Claudio Raimondi et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation

(2016) Lise Roth et al.   Science Signaling

VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

(2016) Xiujuan Li et al.   Nature Communications

Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation

(2016) Lise Roth et al.   Science Signaling

Semaphorin Signaling in Cardiovascular Development

(2015) Jonathan A. Epstein et al.   Cell Metabolism

VEGFR3 does not sustain retinal angiogenesis without VEGFR2

(2015) Georgia Zarkada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular pathogenesis of retinal and choroidal vascular diseases

(2015) Peter A. Campochiaro   PROGRESS IN RETINAL AND EYE RESEARCH

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch

(2015) Irene Maria Aspalter et al.   Nature Communications

NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells

(2015) Alessandro Fantin et al.   Cell Reports

The Neuropilin-1 Inhibitor, ATWLPPR Peptide, Prevents Experimental Diabetes-Induced Retinal Injury by Preserving Vascular Integrity and Decreasing Oxidative Stress

(2015) Jun Wang et al.   PLoS One

Neuropilin regulation of angiogenesis: Figure 1

(2014) Anastasia Lampropoulou et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis

(2014) A. Fantin et al.   DEVELOPMENT

Differential Apicobasal VEGF Signaling at Vascular Blood-Neural Barriers

(2014) Natalie Hudson et al.   DEVELOPMENTAL CELL

Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1–dependent ABL1 activation in endothelial cells

(2014) Claudio Raimondi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Capable ABL: What Is Its Biological Function?

(2014) J. Y. J. Wang   MOLECULAR AND CELLULAR BIOLOGY

Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding

(2014) Maria V Gelfand et al.   eLife

Claudin-5 Controls Intercellular Barriers of Human Dermal Microvascular but Not Human Umbilical Vein Endothelial Cells

(2013) Martin S. Kluger et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery

(2013) Yinghong Gao et al.   BIOCHEMICAL JOURNAL

NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis

(2013) A. Fantin et al.   BLOOD

Neuron-Derived Semaphorin 3A Is an Early Inducer of Vascular Permeability in Diabetic Retinopathy via Neuropilin-1

(2013) Agustin Cerani et al.   Cell Metabolism

Vascular endothelial growth factors (VEGFs) and stroke

(2013) David A. Greenberg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Neuropilin 1 Cytoplasmic Domain Is Required for VEGF-A-Dependent Arteriogenesis

(2013) Anthony Lanahan et al.   DEVELOPMENTAL CELL

Abl Family Kinases Regulate Endothelial Barrier Function In Vitro and in Mice

(2013) Elizabeth M. Chislock et al.   PLoS One

Vascular Endothelial Growth Factor in Acute Lung Injury and Acute Respiratory Distress Syndrome

(2013) S. Barratt et al.   RESPIRATION

c-ABL modulates MAP kinases activation downstream of VEGFR-2 signaling by direct phosphorylation of the adaptor proteins GRB2 and NCK1

(2012) Francesca Anselmi et al.   ANGIOGENESIS

Neuropilin-1Stimulates Tumor Growth by Increasing Fibronectin Fibril Assembly in the Tumor Microenvironment

(2012) Usman Yaqoob et al.   CANCER RESEARCH

Effective Treatment of Edema and Endothelial Barrier Dysfunction With Imatinib

(2012) Jurjan Aman et al.   CIRCULATION

VEGF-Induced Vascular Permeability Is Mediated by FAK

(2012) Xiao Lei Chen et al.   DEVELOPMENTAL CELL

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd

(2012) Zuyue Sun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effects of vascular endothelial growth factor in ischemic stroke

(2012) Yihui Ma et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins

(2011) A. Fantin et al.   DEVELOPMENT

VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels

(2011) A. Cariboni et al.   DEVELOPMENT

Comprehensive analysis of kinase inhibitor selectivity

(2011) Mindy I Davis et al.   NATURE BIOTECHNOLOGY

Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

(2010) A. Fantin et al.   BLOOD

Activation State-Dependent Binding of Small Molecule Kinase Inhibitors: Structural Insights from Biochemistry

(2010) Lisa M. Wodicka et al.   CHEMISTRY & BIOLOGY

An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris

(2009) M. Saint-Geniez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration

(2009) T. Teesalu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor

(2008) L. M. Acevedo et al.   BLOOD

Neuropilin-1-VEGFR-2 Complexing Requires the PDZ-binding Domain of Neuropilin-1

(2008) Claudia Prahst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of adherens junctions and VE-cadherin in the control of vascular permeability

(2008) E. Dejana et al.   JOURNAL OF CELL SCIENCE

Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits

(2008) Lea Scheppke et al.   JOURNAL OF CLINICAL INVESTIGATION