Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1–dependent ABL1 activation in endothelial cells

Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis

(2014) A. Fantin et al.   DEVELOPMENT

VEGF-A Is Necessary and Sufficient for Retinal Neuroprotection in Models of Experimental Glaucoma

(2013) Richard H. Foxton et al.   AMERICAN JOURNAL OF PATHOLOGY

NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis

(2013) A. Fantin et al.   BLOOD

Filopodia are dispensable for endothelial tip cell guidance

(2013) Li-Kun Phng et al.   DEVELOPMENT

The Neuropilin 1 Cytoplasmic Domain Is Required for VEGF-A-Dependent Arteriogenesis

(2013) Anthony Lanahan et al.   DEVELOPMENTAL CELL

Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer

(2013) Jonathan Welti et al.   JOURNAL OF CLINICAL INVESTIGATION

Ocular neovascularization

(2013) Peter A. Campochiaro   JOURNAL OF MOLECULAR MEDICINE-JMM

Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival

(2013) E. M. Chislock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuropilin signalling in vessels, neurons and tumours

(2013) Claudio Raimondi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A Brief History of Anti-VEGF for the Treatment of Ocular Angiogenesis

(2012) Leo A. Kim et al.   AMERICAN JOURNAL OF PATHOLOGY

c-ABL modulates MAP kinases activation downstream of VEGFR-2 signaling by direct phosphorylation of the adaptor proteins GRB2 and NCK1

(2012) Francesca Anselmi et al.   ANGIOGENESIS

Neuropilin-1Stimulates Tumor Growth by Increasing Fibronectin Fibril Assembly in the Tumor Microenvironment

(2012) Usman Yaqoob et al.   CANCER RESEARCH

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway

(2012) Guanglei Zhuang et al.   EMBO JOURNAL

Signal transduction by vascular endothelial growth factor receptors

(2011) Sina Koch et al.   BIOCHEMICAL JOURNAL

Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output

(2011) K. Ballmer-Hofer et al.   BLOOD

The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins

(2011) A. Fantin et al.   DEVELOPMENT

Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis

(2011) D. Stenzel et al.   DEVELOPMENT

VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation

(2011) Birger Herzog et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

(2010) A. Fantin et al.   BLOOD

VEGF Receptor 2 Endocytic Trafficking Regulates Arterial Morphogenesis

(2010) Anthony A. Lanahan et al.   DEVELOPMENTAL CELL

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

(2010) Tom T. Chen et al.   JOURNAL OF CELL BIOLOGY

ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish

(2010) Bin Ren et al.   JOURNAL OF CLINICAL INVESTIGATION

ABL Tyrosine Kinases: Evolution of Function, Regulation, and Specificity

(2010) J. Colicelli   Science Signaling

c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration

(2009) Anna Baruzzi et al.   FEBS LETTERS

αvβ3 Integrin Limits the Contribution of Neuropilin-1 to Vascular Endothelial Growth Factor-induced Angiogenesis

(2009) Stephen D. Robinson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

c-Abl Kinase Is Required for  2 Integrin-Mediated Neutrophil Adhesion

(2009) L. Cui et al.   JOURNAL OF IMMUNOLOGY

Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis

(2009) Kip M Connor et al.   Nature Protocols

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

(2009) Donatella Valdembri et al.   PLOS BIOLOGY

Paxillin Is Involved in the Differential Regulation of Endothelial Barrier by HGF and VEGF

(2008) Anna A. Birukova et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

(2008) H. Kawamura et al.   BLOOD

Vascular Endothelial Growth Factor and Semaphorin Induce Neuropilin-1 Endocytosis via Separate Pathways

(2008) Anna Salikhova et al.   CIRCULATION RESEARCH

Endogenous VEGF Is Required for Visual Function: Evidence for a Survival Role on Müller Cells and Photoreceptors

(2008) Magali Saint-Geniez et al.   PLoS One