Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation

Origin, fate and dynamics of macrophages at central nervous system interfaces

(2016) Tobias Goldmann et al.   NATURE IMMUNOLOGY

Cell-type–restricted anti-cytokine therapy: TNF inhibition from one pathogenic source

(2016) Grigory A. Efimov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN

(2016) Diana Legarda et al.   Cell Reports

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity

(2015) Andrew L. Croxford et al.   IMMUNITY

Clonal expansion under the microscope: studying lymphocyte activation and differentiation using live-cell imaging

(2015) Michal Polonsky et al.   IMMUNOLOGY AND CELL BIOLOGY

Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation

(2015) Iftach Shaked et al.   NATURE IMMUNOLOGY

IL-23-mediated mononuclear phagocyte crosstalk protects mice from Citrobacter rodentium-induced colon immunopathology

(2015) Tegest Aychek et al.   Nature Communications

Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

(2014) Yonit Lavin et al.   CELL

Paradoxical Signaling by a Secreted Molecule Leads to Homeostasis of Cell Levels

(2014) Yuval Hart et al.   CELL

Network dynamics determine the autocrine and paracrine signaling functions of TNF

(2014) Andrew B. Caldwell et al.   GENES & DEVELOPMENT

Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammation

(2014) Debayon Paul et al.   Journal of Neuroinflammation

Antibody-Mediated Inhibition of TNFR1 Attenuates Disease in a Mouse Model of Multiple Sclerosis

(2014) Sarah K. Williams et al.   PLoS One

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

(2014) D. A. Jaitin et al.   SCIENCE

Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice

(2013) Maulik D. Majmudar et al.   CIRCULATION

Origin of monocytes and macrophages in a committed progenitor

(2013) Jan Hettinger et al.   NATURE IMMUNOLOGY

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Autocrine TNF Is Critical for the Survival of Human Dendritic Cells by Regulating BAK, BCL-2, and FLIPL

(2012) M. Lehner et al.   JOURNAL OF IMMUNOLOGY

Monitoring the dynamics of primary T cell activation and differentiation using long term live cell imaging in microwell arrays

(2012) Irina Zaretsky et al.   LAB ON A CHIP

Communication between pathogenic T cells and myeloid cells in neuroinflammatory disease

(2012) Laura Codarri et al.   TRENDS IN IMMUNOLOGY

Pathogenic and Protective Functions of TNF in Neuroinflammation Are Defined by Its Expression in T Lymphocytes and Myeloid Cells

(2011) A. A. Kruglov et al.   JOURNAL OF IMMUNOLOGY

Tumor necrosis factor alpha (TNF-α), anti-TNF-α and demyelination revisited: An ongoing story

(2011) Ana Caminero et al.   JOURNAL OF NEUROIMMUNOLOGY

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

(2010) Áine C. Murphy et al.   BRAIN BEHAVIOR AND IMMUNITY

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

(2009) Alexander Mildner et al.   BRAIN

Characterization of relapsing-remitting and chronic forms of experimental autoimmune encephalomyelitis in C57BL/6 mice

(2009) Jennifer L. Berard et al.   GLIA

Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice

(2009) Ravid Shechter et al.   PLOS MEDICINE